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Adapting a PET Imaging Agent for Correlative Microscopy of Meningiomas and Other Intracranial Tumors

Microscopy and microanalysis, 2012-07, Vol.18 (S2), p.178-179

2012

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Cell‐free assays for γ‐secretase activity

The FASEB journal, 2000-12, Vol.14 (15), p.2383-2386

2000

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Peptide Nucleic Acids Targeted to the Neurotensin Receptor and Administered i.p. Cross the Blood-Brain Barrier and Specifically Reduce Gene Expression

Proceedings of the National Academy of Sciences - PNAS, 1999-06, Vol.96 (12), p.7053-7058

1999

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Systemic and intestinal pharmacokinetics of methotrexate in patients with inflammatory bowel disease

Clinical pharmacology and therapeutics, 1999-01, Vol.65 (1), p.29-39

1999

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In vitro binding and CNS effects of novel neurotensin agonists that cross the blood–brain barrier

Neuropharmacology, 1999-07, Vol.38 (7), p.1027-1034

1999

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Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

The Journal of biological chemistry, 2003-08, Vol.278 (34), p.31831-31837

2003

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Diverse compounds mimic Alzheimer disease-causing mutations by augmenting A beta 42 production

Nature medicine, 2005-05, Vol.11 (5), p.545-550

2005

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Quantitative Measurement of Porphobilinogen in Urine by Stable-Isotope Dilution Liquid Chromatography-Tandem Mass Spectrometry

Clinical chemistry (Baltimore, Md.), 2001-09, Vol.47 (9), p.1627-1632

2001

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Cisplatin and dimethyl sulfoxide react to form an adducted compound with reduced cytotoxicity and neurotoxicity

Neurotoxicology (Park Forest South), 2008-05, Vol.29 (3), p.444-452

2008

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Synthesis of 1D-3-deoxy-, 1D-2,3-dideoxy-, and 1D-2,3,6-trideoxy-myo-inositol 1,4,5-trisphosphate from quebrachitol, their binding affinities, and calcium release activity

Journal of the American Chemical Society, 1993-06, Vol.115 (11), p.4429-4434

1993

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Inhibition of Recombinant Human Mitochondrial Aldehyde Dehydrogenase by Two Intermediate Metabolites of Disulfiram

Biochemical pharmacology, 1998-04, Vol.55 (7), p.1099-1103

1998

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Notch1 augments NF-κB activity by facilitating its nuclear retention

The EMBO journal, 2006-01, Vol.25 (1), p.129-138

2006

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S-Methyl-N,N-Diethylthiocarbamate Sulfoxide and S-Methyl-N,N-Diethylthiocarbamate Sulfone, Two Candidates for the Active Metabolite of Disulfiram

Alcoholism, clinical and experimental research, 1996-05, Vol.20 (3), p.595-600

1996

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Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

Nature immunology, 2005-07, Vol.6 (7), p.680-688

2005

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A Signal Peptide Peptidase (SPP) Reporter Activity Assay Based on the Cleavage of Type II Membrane Protein Substrates Provides Further Evidence for an Inverted Orientation of the SPP Active Site Relative to Presenilin

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.43148-43156

2004

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Unmasking Tandem Site Interaction in Human Acetylcholinesterase. Substrate Activation with a Cationic Acetanilide Substrate

Biochemistry (Easton), 2003-05, Vol.42 (18), p.5438-5452

2003

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An Empirical Model of γ-Secretase Activity

Annals of the New York Academy of Sciences, 2000-01, Vol.920 (1), p.233-240

2000

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S-Methyl N, N-diethylthiocarbamate sulfone, a potential metabolite of disulfiram and potent inhibitor of low Km mitochondrial aldehyde dehydrogenase

Biochemical pharmacology, 1995-03, Vol.49 (5), p.693-700

1995

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A novel neurotensin analog blocks cocaine- and d-amphetamine-induced hyperactivity

European journal of pharmacology, 2001-08, Vol.426 (1), p.73-76

2001

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Inhibitors Tethered Near the Acetylcholinesterase Active Site Serve as Molecular Rulers of the Peripheral and Acylation Sites

The Journal of biological chemistry, 2003-10, Vol.278 (40), p.38948-38955

2003

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Cloning of a cDNA for Short/Branched Chain Acyl-Coenzyme A Dehydrogenase from Rat and Characterization of Its Tissue Expression and Substrate Specificity

Archives of biochemistry and biophysics, 1996-07, Vol.331 (1), p.127-133

1996

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Cellular pharmacology of D-3-azido-3-deoxy-myo-inositol, an inhibitor of phosphatidylinositol signaling having antiproliferative activity

Cancer chemotherapy and pharmacology, 1994-01, Vol.35 (1), p.71-79

1994

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Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage

The Journal of biological chemistry, 2000-08, Vol.275 (34), p.26277-26284

2000

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Antiparkinson-like effects of a novel neurotensin analog in unilaterally 6-hydroxydopamine lesioned rats

European journal of pharmacology, 2001-10, Vol.428 (2), p.227-233

2001

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D-3-deoxy-3-substituted myo-inositol analogues as inhibitors of cell growth

Cancer chemotherapy and pharmacology, 1991, Vol.29 (2), p.95-104

1991

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Adapting a PET Imaging Agent for Correlative Microscopy of Meningiomas and Other Intracranial Tumors

Cell‐free assays for γ‐secretase activity

Peptide Nucleic Acids Targeted to the Neurotensin Receptor and Administered i.p. Cross the Blood-Brain Barrier and Specifically Reduce Gene Expression

Systemic and intestinal pharmacokinetics of methotrexate in patients with inflammatory bowel disease

In vitro binding and CNS effects of novel neurotensin agonists that cross the blood–brain barrier

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

Diverse compounds mimic Alzheimer disease-causing mutations by augmenting A beta 42 production

Quantitative Measurement of Porphobilinogen in Urine by Stable-Isotope Dilution Liquid Chromatography-Tandem Mass Spectrometry

Cisplatin and dimethyl sulfoxide react to form an adducted compound with reduced cytotoxicity and neurotoxicity

Synthesis of 1D-3-deoxy-, 1D-2,3-dideoxy-, and 1D-2,3,6-trideoxy-myo-inositol 1,4,5-trisphosphate from quebrachitol, their binding affinities, and calcium release activity

Inhibition of Recombinant Human Mitochondrial Aldehyde Dehydrogenase by Two Intermediate Metabolites of Disulfiram

Notch1 augments NF-κB activity by facilitating its nuclear retention

S-Methyl-N,N-Diethylthiocarbamate Sulfoxide and S-Methyl-N,N-Diethylthiocarbamate Sulfone, Two Candidates for the Active Metabolite of Disulfiram

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

A Signal Peptide Peptidase (SPP) Reporter Activity Assay Based on the Cleavage of Type II Membrane Protein Substrates Provides Further Evidence for an Inverted Orientation of the SPP Active Site Relative to Presenilin

Unmasking Tandem Site Interaction in Human Acetylcholinesterase. Substrate Activation with a Cationic Acetanilide Substrate

An Empirical Model of γ-Secretase Activity

S-Methyl N, N-diethylthiocarbamate sulfone, a potential metabolite of disulfiram and potent inhibitor of low Km mitochondrial aldehyde dehydrogenase

A novel neurotensin analog blocks cocaine- and d-amphetamine-induced hyperactivity

Inhibitors Tethered Near the Acetylcholinesterase Active Site Serve as Molecular Rulers of the Peripheral and Acylation Sites

Cloning of a cDNA for Short/Branched Chain Acyl-Coenzyme A Dehydrogenase from Rat and Characterization of Its Tissue Expression and Substrate Specificity

Cellular pharmacology of D-3-azido-3-deoxy-myo-inositol, an inhibitor of phosphatidylinositol signaling having antiproliferative activity

Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage

Antiparkinson-like effects of a novel neurotensin analog in unilaterally 6-hydroxydopamine lesioned rats

D-3-deoxy-3-substituted myo-inositol analogues as inhibitors of cell growth

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