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Key tissue targets responsible for anthrax-toxin-induced lethality

Nature (London), 2013-09, Vol.501 (7465), p.63-68

2013

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Key tissue targets responsible for anthrax-toxin-induced lethality

Nature (London), 2013-08, Vol.501 (7465), p.63-68

2013

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Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome

PLoS pathogens, 2012-03, Vol.8 (3), p.e1002638-e1002638

2012

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Solid tumor therapy by selectively targeting stromal endothelial cells

Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (28), p.E4079-E4087

2016

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Imaging of anthrax intoxication in mice reveals shared and individual functions of surface receptors CMG-2 and TEM-8 in cellular toxin entry

The Journal of biological chemistry, 2022-01, Vol.298 (1), p.101467-101467, Article 101467

2022

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The Bacillus cereus Hbl and Nhe tripartite enterotoxin components assemble sequentially on the surface of target cells and are not interchangeable

PloS one, 2013-10, Vol.8 (10), p.e76955

2013

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Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages

PloS one, 2012-11, Vol.7 (11), p.e49741

2012

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Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse development

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (34), p.13817-13822

2012

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Role of N-terminal amino acids in the potency of anthrax lethal factor

PloS one, 2008-09, Vol.3 (9), p.e3130-e3130

2008

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Anthrax edema factor toxicity is strongly mediated by the N-end rule

PloS one, 2013-08, Vol.8 (8), p.e74474-e74474

2013

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Bismaleimide cross‐linked anthrax toxin forms functional octamers with high specificity in tumor targeting

Protein science, 2019-06, Vol.28 (6), p.1059-1070

2019

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Genome engineering in Bacillus anthracis using tyrosine site-specific recombinases

PloS one, 2017-08, Vol.12 (8), p.e0183346-e0183346

2017

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Engineering Anthrax Toxin Variants That Exclusively Form Octamers and Their Application to Targeting Tumors

The Journal of biological chemistry, 2013-03, Vol.288 (13), p.9058-9065

2013

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Anthrax toxin-mediated delivery of the Pseudomonas exotoxin A enzymatic domain to the cytosol of tumor cells via cleavable ubiquitin fusions

mBio, 2013-04, Vol.4 (3), p.e00201

2013

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Recombinant expression and purification of a tumor-targeted toxin in Bacillus anthracis

Biochemical and biophysical research communications, 2013-01, Vol.430 (1), p.150-155

2013

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A Bacillus anthracis strain deleted for six proteases serves as an effective host for production of recombinant proteins

Protein expression and purification, 2011-11, Vol.80 (1), p.80-90

2011

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Anthrax lethal factor cleaves regulatory subunits of phosphoinositide-3 kinase to contribute to toxin lethality

Nature microbiology, 2020-12, Vol.5 (12), p.1464

2020

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Reductive methylation and mutation of an anthrax toxin fusion protein modulates its stability and cytotoxicity

Scientific reports, 2014-04, Vol.4 (1), p.4754, Article 4754

2014

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Mouse Monoclonal Antibodies to Anthrax Edema Factor Protect against Infection

Infection and Immunity, 2011-11, Vol.79 (11), p.4609-4616

2011

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APRIL and BAFF Promote Increased Viability of Replicating Human B2 Cells via Mechanism Involving Cyclooxygenase 2

Journal of Immunology, 2006-06, Vol.176 (11), p.6736-6751

2006

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Abstract 1498 Environmental Regulation of Toxin Production in Bacillus Anthracis

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.106441, Article 106441

2024

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Benzamide-Based Thiolcarbamates: A New Class of HIV-1 NCp7 Inhibitors

Bioorganic & medicinal chemistry letters, 2002-03, Vol.12 (5), p.767-770

2002

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Role of Complement-Binding CD21/CD19/CD81 in Enhancing Human B Cell Protection from Fas-Mediated Apoptosis

The Journal of immunology (1950), 2003-11, Vol.171 (10), p.5244-5254

2003

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Innate Immunity and Human B Cell Clonal Expansion: Effects on the Recirculating B2 Subpopulation

The Journal of immunology (1950), 2005-11, Vol.175 (9), p.6143-6154

2005

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Optimization of unique, uncharged thioesters as inhibitors of HIV replication

Bioorganic & medicinal chemistry, 2004-12, Vol.12 (24), p.6437-6450

2004

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Key tissue targets responsible for anthrax-toxin-induced lethality

Key tissue targets responsible for anthrax-toxin-induced lethality

Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome

Solid tumor therapy by selectively targeting stromal endothelial cells

Imaging of anthrax intoxication in mice reveals shared and individual functions of surface receptors CMG-2 and TEM-8 in cellular toxin entry

The Bacillus cereus Hbl and Nhe tripartite enterotoxin components assemble sequentially on the surface of target cells and are not interchangeable

Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages

Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse development

Role of N-terminal amino acids in the potency of anthrax lethal factor

Anthrax edema factor toxicity is strongly mediated by the N-end rule

Bismaleimide cross‐linked anthrax toxin forms functional octamers with high specificity in tumor targeting

Genome engineering in Bacillus anthracis using tyrosine site-specific recombinases

Engineering Anthrax Toxin Variants That Exclusively Form Octamers and Their Application to Targeting Tumors

Anthrax toxin-mediated delivery of the Pseudomonas exotoxin A enzymatic domain to the cytosol of tumor cells via cleavable ubiquitin fusions

Recombinant expression and purification of a tumor-targeted toxin in Bacillus anthracis

A Bacillus anthracis strain deleted for six proteases serves as an effective host for production of recombinant proteins

Anthrax lethal factor cleaves regulatory subunits of phosphoinositide-3 kinase to contribute to toxin lethality

Reductive methylation and mutation of an anthrax toxin fusion protein modulates its stability and cytotoxicity

Mouse Monoclonal Antibodies to Anthrax Edema Factor Protect against Infection

APRIL and BAFF Promote Increased Viability of Replicating Human B2 Cells via Mechanism Involving Cyclooxygenase 2

Abstract 1498 Environmental Regulation of Toxin Production in Bacillus Anthracis

Benzamide-Based Thiolcarbamates: A New Class of HIV-1 NCp7 Inhibitors

Role of Complement-Binding CD21/CD19/CD81 in Enhancing Human B Cell Protection from Fas-Mediated Apoptosis

Innate Immunity and Human B Cell Clonal Expansion: Effects on the Recirculating B2 Subpopulation

Optimization of unique, uncharged thioesters as inhibitors of HIV replication

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