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α9‐ and α7‐containing receptors mediate the pro‐proliferative effects of nicotine in the A549 adenocarcinoma cell line

British journal of pharmacology, 2018-06, Vol.175 (11), p.1957-1972

2018

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Neuronal Acetylcholine Nicotinic Receptors as New Targets for Lung Cancer Treatment

Current pharmaceutical design, 2016-04, Vol.22 (14), p.2160-2169

2016

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A Promising PET Tracer for Imaging of α₇ Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand

Molecules (Basel, Switzerland), 2015-10, Vol.20 (10), p.18387-18421

2015

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(+)-Laburnamine, a Natural Selective Ligand and Partial Agonist for the α4β2 Nicotinic Receptor Subtype

Journal of natural products (Washington, D.C.), 2013-04, Vol.76 (4), p.727-731

2013

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Structure of neuronal nicotinic receptors

Current topics in behavioral neurosciences, 2015, Vol.23, p.1

2015

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Choline and nicotine increase glioblastoma cell proliferation by binding and activating α7- and α9- containing nicotinic receptors

Pharmacological research, 2021-01, Vol.163, p.105336-105336, Article 105336

2021

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Reduced α4 subunit expression in α4+− and α4+−/β2+− nicotinic acetylcholine receptors alters α4β2 subtype up‐regulation following chronic nicotine treatment

British journal of pharmacology, 2018-06, Vol.175 (11), p.1944-1956

2018

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Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an α7-nAChR, α9-nAChR Antagonist and of a Pro-Oxidant Mitocan

Journal of medicinal chemistry, 2018-12, Vol.61 (23), p.10531-10544

2018

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Chronic nicotine and withdrawal affect glutamatergic but not nicotinic receptor expression in the mesocorticolimbic pathway in a region-specific manner

Pharmacological research, 2016-01, Vol.103, p.167-176

2016

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Novel 5-substituted 3-hydroxyphenyl and 3-nitrophenyl ethers of S-prolinol as α4β2-nicotinic acetylcholine receptor ligands

Bioorganic & medicinal chemistry letters, 2016-12, Vol.26 (23), p.5613-5617

2016

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Chemistry and Pharmacology of a Series of Unichiral Analogues of 2‑(2-Pyrrolidinyl)-1,4-benzodioxane, Prolinol Phenyl Ether, and Prolinol 3‑Pyridyl Ether Designed as α4β2-Nicotinic Acetylcholine Receptor Agonists

Journal of medicinal chemistry, 2015-08, Vol.58 (16), p.6665-6677

2015

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The cytisine derivatives, CC4 and CC26, reduce nicotine-induced conditioned place preference in zebrafish by acting on heteromeric neuronal nicotinic acetylcholine receptors

Psychopharmacology, 2014-12, Vol.231 (24), p.4681-4693

2014

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Pyridinyl- and pyridazinyl-3,6-diazabicyclo[3.1.1]heptane-anilines: Novel selective ligands with subnanomolar affinity for α4β2 nACh receptors

European journal of medicinal chemistry, 2018-05, Vol.152, p.401-416

2018

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Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

European journal of medicinal chemistry, 2016-01, Vol.108, p.392-405

2016

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From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at α4β2 nicotinic acetylcholine receptor

European journal of medicinal chemistry, 2017-01, Vol.125, p.1132-1144

2017

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CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation

British journal of pharmacology, 2013-02, Vol.168 (4), p.835-849

2013

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CC4, a dimer of cytisine, is a selective partial agonist at alpha 4 beta 2/ alpha 6 beta 2 nAChR with improved selectivity for tobacco smoking cessation

British journal of pharmacology, 2013-02, Vol.168 (4), p.835-849

2013

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Nicotinic receptors increase cell proliferation and tumour progression in non-small cell lung cancer cell line

Biochemical pharmacology, 2015-10, Vol.97 (4), p.631-631

2015

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Synthesis and Pharmacological Evaluation of α 4 β 2 Nicotinic Ligands with a 3‐Fluoropyrrolidine Nucleus

ChemMedChem, 2015-06, Vol.10 (6), p.1071-1078

2015

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Synthesis and Pharmacological Evaluation of [alpha]4[beta]2 Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus

ChemMedChem, 2015-06, Vol.10 (6), p.1071

2015

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Design of novel 3,6-diazabicyclo[3.1.1]heptane derivatives with potent and selective affinities for α4β2 neuronal nicotinic acetylcholine receptors

European journal of medicinal chemistry, 2015-10, Vol.103, p.429-437

2015

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Design, synthesis and binding affinity of acetylcholine carbamoyl analogues

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (23), p.6481-6485

2013

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Synthesis and Pharmacological Evaluation of α4β2 Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus

ChemMedChem, 2015-06, Vol.10 (6), p.1071-1078

2015

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Pyridinyl- and pyridazinyl-3,6-diazabicyclo[3.1.1]heptane-anilines: Novel selective ligands with subnanomolar affinity for α 4 β 2 nACh receptors

European journal of medicinal chemistry, 2018-05, Vol.152, p.401

2018

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CC4, a dimer of cytisine, is a selective partial agonist at [alpha]4[beta]2/[alpha]6[beta]2 nAChR with improved selectivity for tobacco smoking cessation

British journal of pharmacology, 2013-02, Vol.168 (4), p.835

2013

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α9‐ and α7‐containing receptors mediate the pro‐proliferative effects of nicotine in the A549 adenocarcinoma cell line

Neuronal Acetylcholine Nicotinic Receptors as New Targets for Lung Cancer Treatment

A Promising PET Tracer for Imaging of α₇ Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand

(+)-Laburnamine, a Natural Selective Ligand and Partial Agonist for the α4β2 Nicotinic Receptor Subtype

Structure of neuronal nicotinic receptors

Choline and nicotine increase glioblastoma cell proliferation by binding and activating α7- and α9- containing nicotinic receptors

Reduced α4 subunit expression in α4+− and α4+−/β2+− nicotinic acetylcholine receptors alters α4β2 subtype up‐regulation following chronic nicotine treatment

Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an α7-nAChR, α9-nAChR Antagonist and of a Pro-Oxidant Mitocan

Chronic nicotine and withdrawal affect glutamatergic but not nicotinic receptor expression in the mesocorticolimbic pathway in a region-specific manner

Novel 5-substituted 3-hydroxyphenyl and 3-nitrophenyl ethers of S-prolinol as α4β2-nicotinic acetylcholine receptor ligands

Chemistry and Pharmacology of a Series of Unichiral Analogues of 2‑(2-Pyrrolidinyl)-1,4-benzodioxane, Prolinol Phenyl Ether, and Prolinol 3‑Pyridyl Ether Designed as α4β2-Nicotinic Acetylcholine Receptor Agonists

The cytisine derivatives, CC4 and CC26, reduce nicotine-induced conditioned place preference in zebrafish by acting on heteromeric neuronal nicotinic acetylcholine receptors

Pyridinyl- and pyridazinyl-3,6-diazabicyclo[3.1.1]heptane-anilines: Novel selective ligands with subnanomolar affinity for α4β2 nACh receptors

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at α4β2 nicotinic acetylcholine receptor

CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation

CC4, a dimer of cytisine, is a selective partial agonist at alpha 4 beta 2/ alpha 6 beta 2 nAChR with improved selectivity for tobacco smoking cessation

Nicotinic receptors increase cell proliferation and tumour progression in non-small cell lung cancer cell line

Synthesis and Pharmacological Evaluation of α 4 β 2 Nicotinic Ligands with a 3‐Fluoropyrrolidine Nucleus

Synthesis and Pharmacological Evaluation of [alpha]4[beta]2 Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus

Design of novel 3,6-diazabicyclo[3.1.1]heptane derivatives with potent and selective affinities for α4β2 neuronal nicotinic acetylcholine receptors

Design, synthesis and binding affinity of acetylcholine carbamoyl analogues

Synthesis and Pharmacological Evaluation of α4β2 Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus

Pyridinyl- and pyridazinyl-3,6-diazabicyclo[3.1.1]heptane-anilines: Novel selective ligands with subnanomolar affinity for α 4 β 2 nACh receptors

CC4, a dimer of cytisine, is a selective partial agonist at [alpha]4[beta]2/[alpha]6[beta]2 nAChR with improved selectivity for tobacco smoking cessation

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