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Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling

Nature communications, 2019-11, Vol.10 (1), p.5016-15, Article 5016

2019

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Regulation of Breast Cancer Stem Cell Activity by Signaling through the Notch4 Receptor

Cancer research (Chicago, Ill.), 2010-01, Vol.70 (2), p.709-718

2010

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PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression

Cell reports (Cambridge), 2017-12, Vol.21 (12), p.3498-3513

2017

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A Detailed Mammosphere Assay Protocol for the Quantification of Breast Stem Cell Activity

Journal of mammary gland biology and neoplasia, 2012-06, Vol.17 (2), p.111-117

2012

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Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms

Clinical cancer research, 2013-02, Vol.19 (3), p.643-656

2013

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Discovery of an MLLT1/3 YEATS Domain Chemical Probe

Angewandte Chemie International Edition, 2018-12, Vol.57 (50), p.16302-16307

International ed. in English, 2018

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Focal Adhesion Kinase and Wnt Signaling Regulate Human Ductal Carcinoma In Situ Stem Cell Activity and Response to Radiotherapy

Stem cells (Dayton, Ohio), 2015-02, Vol.33 (2), p.327-341

2015

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PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo

Scientific reports, 2024-01, Vol.14 (1), p.328-328, Article 328

2024

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FAK inhibition alone or in combination with adjuvant therapies reduces cancer stem cell activity

NPJ breast cancer, 2021-05, Vol.7 (1), p.65-65, Article 65

2021

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Combined inhibition of ErbB1/2 and Notch receptors effectively targets breast ductal carcinoma in situ (DCIS) stem/progenitor cell activity regardless of ErbB2 status

PloS one, 2013-02, Vol.8 (2), p.e56840-e56840

2013

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Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9

SLAS discovery, 2019-02, Vol.24 (2), p.133-141

2019

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A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity

Oncotarget, 2014-02, Vol.5 (3), p.599-612

2014

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RNA-Seq analysis of early transcriptional responses to activation in the leukaemic Jurkat E6.1 T cell line

Wellcome open research, 2020-01, Vol.5, p.42

2020

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Lapatinib inhibits stem/progenitor proliferation in preclinical in vitro models of ductal carcinoma in situ (DCIS)

Cell cycle (Georgetown, Tex.), 2014-02, Vol.13 (3), p.418-425

2014

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The Mitogenic Action of Insulin-like Growth Factor I in Normal Human Mammary Epithelial Cells Requires the Epidermal Growth Factor Receptor Tyrosine Kinase

The Journal of biological chemistry, 2004-01, Vol.279 (3), p.1713-1719

2004

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Small-Molecule Inhibitors of the MDM2-p53 Protein−Protein Interaction Based on an Isoindolinone Scaffold

Journal of medicinal chemistry, 2006-10, Vol.49 (21), p.6209-6221

2006

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High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant

Oncotarget, 2015-10, Vol.6 (31), p.30472-30486

2015

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Isoindolinone-based inhibitors of the MDM2–p53 protein–protein interaction

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (5), p.1515-1520

2005

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Mammary stem cells and breast cancer--role of Notch signalling

Stem cell reviews, 2007-06, Vol.3 (2), p.169-175

2007

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A novel preclinical model of the normal human breast

Journal of mammary gland biology and neoplasia, 2024-12, Vol.29 (1), p.9-9, Article 9

2024

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Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells

Breast cancer research : BCR, 2013-01, Vol.15 (4), p.210-210, Article 210

2013

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Novel Inhibitors of MLLT1/3, a Critical Component of the Super-Elongation Complex (SEC), Target a Range of Molecularly Defined Acute Leukemias, with a Differential Profile to Menin Inhibition

Blood, 2023-11, Vol.142 (Supplement 1), p.2789-2789

2023

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Abstract 3025: PRMT5 inhibition reduces viability and stemness of pediatric high grade glioma

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.3025-3025

2021

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In vitro evidence for the role of procoagulant stromal fibroblasts in the development of breast cancer

European journal of surgical oncology, 2017-05, Vol.43 (5), p.S15-S15

2017

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Evidence for the role of procoagulant stromal fibroblasts in the progression of Ductal Carcinoma in Situ

European journal of surgical oncology, 2018-06, Vol.44 (6), p.891-892

2018

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Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling

Regulation of Breast Cancer Stem Cell Activity by Signaling through the Notch4 Receptor

PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression

A Detailed Mammosphere Assay Protocol for the Quantification of Breast Stem Cell Activity

Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms

Discovery of an MLLT1/3 YEATS Domain Chemical Probe

Focal Adhesion Kinase and Wnt Signaling Regulate Human Ductal Carcinoma In Situ Stem Cell Activity and Response to Radiotherapy

PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo

FAK inhibition alone or in combination with adjuvant therapies reduces cancer stem cell activity

Combined inhibition of ErbB1/2 and Notch receptors effectively targets breast ductal carcinoma in situ (DCIS) stem/progenitor cell activity regardless of ErbB2 status

Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9

A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity

RNA-Seq analysis of early transcriptional responses to activation in the leukaemic Jurkat E6.1 T cell line

Lapatinib inhibits stem/progenitor proliferation in preclinical in vitro models of ductal carcinoma in situ (DCIS)

The Mitogenic Action of Insulin-like Growth Factor I in Normal Human Mammary Epithelial Cells Requires the Epidermal Growth Factor Receptor Tyrosine Kinase

Small-Molecule Inhibitors of the MDM2-p53 Protein−Protein Interaction Based on an Isoindolinone Scaffold

High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant

Isoindolinone-based inhibitors of the MDM2–p53 protein–protein interaction

Mammary stem cells and breast cancer--role of Notch signalling

A novel preclinical model of the normal human breast

Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells

Novel Inhibitors of MLLT1/3, a Critical Component of the Super-Elongation Complex (SEC), Target a Range of Molecularly Defined Acute Leukemias, with a Differential Profile to Menin Inhibition

Abstract 3025: PRMT5 inhibition reduces viability and stemness of pediatric high grade glioma

In vitro evidence for the role of procoagulant stromal fibroblasts in the development of breast cancer

Evidence for the role of procoagulant stromal fibroblasts in the progression of Ductal Carcinoma in Situ

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