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Therapeutic Dissolution of Aberrant Phases by Nuclear-Import Receptors

Trends in cell biology, 2019-04, Vol.29 (4), p.308-322

2019

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Higher-order organization of biomolecular condensates

Open biology, 2021-06, Vol.11 (6), p.210137-210137

2021

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Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations

Molecular cell, 2020-01, Vol.77 (1), p.82-94.e4

2020

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(Dis)Solving the problem of aberrant protein states

Disease models & mechanisms, 2021-05, Vol.14 (5)

2021

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Nuclear pore dysfunction and disease: a complex opportunity

Nucleus (Austin, Tex.), 2024-12, Vol.15 (1), p.2314297-2314297

2024

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Nuclear-Import Receptors Counter Deleterious Phase Transitions in Neurodegenerative Disease

Journal of molecular biology, 2022-01, Vol.434 (1), p.167220-167220, Article 167220

2022

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Open Access: A Role for p53 in c9ALS/FTD?

Trends in genetics, 2021-05, Vol.37 (5), p.404-406

2021

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A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity

The Journal of biological chemistry, 2023-02, Vol.299 (2), p.102806, Article 102806

2023

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Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains

Cell, 2018-04, Vol.173 (3), p.677-692.e20

2018

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Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions

Cell reports (Cambridge), 2020-12, Vol.33 (12), p.108538-108538, Article 108538

2020

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ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS

Molecular cell, 2020-11, Vol.80 (4), p.666-681.e8

2020

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Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation

Molecular cell, 2022-07, Vol.82 (14), p.2588-2603.e9

2022

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Poly(ADP-ribose) drives condensation of FUS via a transient interaction

Molecular cell, 2022-03, Vol.82 (5), p.969-985.e11

2022

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Engineered Nuclear Import Receptor Karyopherin‐β2 Chaperones Aberrant Phase Transitions of Disease‐Associated Cargo

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS

Molecular cell, 2020-12, Vol.80 (6), p.1139-1139

2020

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Pollution Assessment for Sustainable Practices in Applied Sciences and Engineering

1, 2020

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Novel tag-based method for measuring tailbeat frequency and variations in amplitude in fish

Animal biotelemetry, 2023-03, Vol.11 (1), p.1-13, Article 12

2023

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Heart rate and swimming activity as indicators of post-surgical recovery time of Atlantic salmon (Salmo salar)

Animal biotelemetry, 2021-01, Vol.9 (1), p.1-13, Article 3

2021

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Engineered nuclear import receptor karyopherin-B2 chaperones aberrant phase transitions of disease-associated cargo

Biophysical journal, 2022-02, Vol.121 (3), p.156a-156a

2022

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Searching for coeliac disease in patients with non-alcoholic fatty liver disease

Digestive and liver disease, 2004-05, Vol.36 (5), p.333-336

2004

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Liver iron concentration in chronic viral hepatitis: a study of 98 patients

European journal of gastroenterology & hepatology, 1995-12, Vol.7 (12), p.1203-1208

1995

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Genetic hemochromatosis in Italian patients with porphyria cutanea tarda : possible explanation for iron overload

Journal of hepatology, 1996-05, Vol.24 (5), p.564-569

1996

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An immunogenetic map of Lombardy (Northern Italy)

Annals of human genetics, 2002-01, Vol.66 (1), p.37-48

2002

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The Post-observation Conference: An Exploration of Feedback Strategies

Fare, Dennis M

2021

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Therapeutic Dissolution of Aberrant Phases by Nuclear-Import Receptors

Higher-order organization of biomolecular condensates

Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations

(Dis)Solving the problem of aberrant protein states

Nuclear pore dysfunction and disease: a complex opportunity

Characterization of HNRNPA1 mutations defines diversity in pathogenic mechanisms and clinical presentation

Nuclear-Import Receptors Counter Deleterious Phase Transitions in Neurodegenerative Disease

Open Access: A Role for p53 in c9ALS/FTD?

A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity

Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains

Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions

ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS

Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation

Poly(ADP-ribose) drives condensation of FUS via a transient interaction

Engineered Nuclear Import Receptor Karyopherin‐β2 Chaperones Aberrant Phase Transitions of Disease‐Associated Cargo

ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS

Pollution Assessment for Sustainable Practices in Applied Sciences and Engineering

Novel tag-based method for measuring tailbeat frequency and variations in amplitude in fish

Heart rate and swimming activity as indicators of post-surgical recovery time of Atlantic salmon (Salmo salar)

Engineered nuclear import receptor karyopherin-B2 chaperones aberrant phase transitions of disease-associated cargo

Searching for coeliac disease in patients with non-alcoholic fatty liver disease

Liver iron concentration in chronic viral hepatitis: a study of 98 patients

Genetic hemochromatosis in Italian patients with porphyria cutanea tarda : possible explanation for iron overload

An immunogenetic map of Lombardy (Northern Italy)

The Post-observation Conference: An Exploration of Feedback Strategies

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