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An Efficient Chemoenzymatic Synthesis of Dihydroartemisinic Aldehyde

Angewandte Chemie International Edition, 2017-04, Vol.56 (15), p.4347-4350

International ed. in English, 2017

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Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency

Biochemical journal, 2013-05, Vol.451 (3), p.417-426

2013

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Emergence of terpene cyclization in Artemisia annua

Nature communications, 2015-02, Vol.6 (1), p.6143-6143, Article 6143

2015

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REVIEW: Epistasis and dominance in the emergence of catalytic function as exemplified by the evolution of plant terpene synthases

Plant science (Limerick), 2017-02, Vol.255, p.29-38

2017

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Doubly Deuterium-Labeled Patchouli Alcohol from Cyclization of Singly Labeled [2-2H1]Farnesyl Diphosphate Catalyzed by Recombinant Patchoulol Synthase

Journal of the American Chemical Society, 2010-03, Vol.132 (9), p.2998-3008

2010

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Conformational analysis of (+)-germacrene A by variable-temperature NMR and NOE spectroscopy

Tetrahedron, 2007-09, Vol.63 (32), p.7733-7742

2007

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Variation in capsidiol sensitivity between Phytophthora infestans and Phytophthora capsici is consistent with their host range

PloS one, 2014-09, Vol.9 (9), p.e107462-e107462

2014

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The role of aristolochene synthase in diphosphate activation

Chemical communications (Cambridge, England), 2012-01, Vol.48 (26), p.3230-3232

2012

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Alternative Synthesis of the Colorado Potato Beetle Pheromone

Journal of organic chemistry, 2013-10, Vol.78 (20), p.10548-10554

2013

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Structural Elucidation of Cisoid and Transoid Cyclization Pathways of a Sesquiterpene Synthase Using 2-Fluorofarnesyl Diphosphates

ACS chemical biology, 2010-04, Vol.5 (4), p.377-392

2010

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X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis

The Journal of biological chemistry, 2008-05, Vol.283 (22), p.15431-15439

2008

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Bisabolyl-Derived Sesquiterpenes from Tobacco 5-Epi-aristolochene Synthase-Catalyzed Cyclization of (2Z,6E)-Farnesyl Diphosphate

Journal of the American Chemical Society, 2010-03, Vol.132 (12), p.4281-4289

2010

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Comparative analysis and validation of the malachite green assay for the high throughput biochemical characterization of terpene synthases

MethodsX, 2014-01, Vol.1 (C), p.187-196

2014

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Evolutionary and Mechanistic Insights from the Reconstruction of α‑Humulene Synthases from a Modern (+)-Germacrene A Synthase

Journal of the American Chemical Society, 2014-10, Vol.136 (41), p.14505-14512

2014

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Mechanistic Insights from the Binding of Substrate and Carbocation Intermediate Analogues to Aristolochene Synthase

Biochemistry (Easton), 2013-08, Vol.52 (32), p.5441-5453

2013

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Probing Eudesmane Cation−π Interactions in Catalysis by Aristolochene Synthase with Non-canonical Amino Acids

Journal of the American Chemical Society, 2011-09, Vol.133 (35), p.13906-13909

2011

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Discovery of germacrene A synthases in Barnadesia spinosa: The first committed step in sesquiterpene lactone biosynthesis in the basal member of the Asteraceae

Biochemical and biophysical research communications, 2016-10, Vol.479 (4), p.622-627

2016

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Chemoenzymatic preparation of germacrene analogues

Chemical communications (Cambridge, England), 2012-01, Vol.48 (78), p.9702-9704

2012

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A 1,6-Ring Closure Mechanism for (+)-δ-Cadinene Synthase?

Journal of the American Chemical Society, 2012-04, Vol.134 (13), p.5900-5908

2012

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Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase

Biochemistry (Easton), 2016-05, Vol.55 (20), p.2864-2874

2016

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The amino-terminal segment in the β-domain of δ-cadinene synthase is essential for catalysis

Organic & biomolecular chemistry, 2016-01, Vol.14 (31), p.7451-7454

2016

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Inhibition of (+)-Aristolochene Synthase with Iminium Salts Resembling Eudesmane Cation

Organic letters, 2011-03, Vol.13 (5), p.1202-1205

2011

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Enzymatic synthesis of natural (+)-aristolochene from a non-natural substrate

Chemical communications (Cambridge, England), 2016-01, Vol.52 (97), p.14027-14030

2016

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Intermediacy of Eudesmane Cation during Catalysis by Aristolochene Synthase

Journal of organic chemistry, 2010-02, Vol.75 (4), p.1119-1125

2010

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Scope and Mechanism of Intramolecular Aziridination of Cyclopent-3-enyl-methylamines to 1-Azatricyclo[2.2.1.02,6]heptanes with Lead Tetraacetate

Journal of the American Chemical Society, 2009-08, Vol.131 (33), p.11998-12006

2009

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An Efficient Chemoenzymatic Synthesis of Dihydroartemisinic Aldehyde

Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency

Emergence of terpene cyclization in Artemisia annua

REVIEW: Epistasis and dominance in the emergence of catalytic function as exemplified by the evolution of plant terpene synthases

Doubly Deuterium-Labeled Patchouli Alcohol from Cyclization of Singly Labeled [2-2H1]Farnesyl Diphosphate Catalyzed by Recombinant Patchoulol Synthase

Conformational analysis of (+)-germacrene A by variable-temperature NMR and NOE spectroscopy

Variation in capsidiol sensitivity between Phytophthora infestans and Phytophthora capsici is consistent with their host range

The role of aristolochene synthase in diphosphate activation

Alternative Synthesis of the Colorado Potato Beetle Pheromone

Structural Elucidation of Cisoid and Transoid Cyclization Pathways of a Sesquiterpene Synthase Using 2-Fluorofarnesyl Diphosphates

X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis

Bisabolyl-Derived Sesquiterpenes from Tobacco 5-Epi-aristolochene Synthase-Catalyzed Cyclization of (2Z,6E)-Farnesyl Diphosphate

Comparative analysis and validation of the malachite green assay for the high throughput biochemical characterization of terpene synthases

Evolutionary and Mechanistic Insights from the Reconstruction of α‑Humulene Synthases from a Modern (+)-Germacrene A Synthase

Mechanistic Insights from the Binding of Substrate and Carbocation Intermediate Analogues to Aristolochene Synthase

Probing Eudesmane Cation−π Interactions in Catalysis by Aristolochene Synthase with Non-canonical Amino Acids

Discovery of germacrene A synthases in Barnadesia spinosa: The first committed step in sesquiterpene lactone biosynthesis in the basal member of the Asteraceae

Chemoenzymatic preparation of germacrene analogues

A 1,6-Ring Closure Mechanism for (+)-δ-Cadinene Synthase?

Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase

The amino-terminal segment in the β-domain of δ-cadinene synthase is essential for catalysis

Inhibition of (+)-Aristolochene Synthase with Iminium Salts Resembling Eudesmane Cation

Enzymatic synthesis of natural (+)-aristolochene from a non-natural substrate

Intermediacy of Eudesmane Cation during Catalysis by Aristolochene Synthase

Scope and Mechanism of Intramolecular Aziridination of Cyclopent-3-enyl-methylamines to 1-Azatricyclo[2.2.1.02,6]heptanes with Lead Tetraacetate

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