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The Biology of Ageing: From Hallmarks to Drugs

Faragher, Richard

2023

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Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing

Biogerontology (Dordrecht), 2018-12, Vol.19 (6), p.447-459

2018

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A SIRT1-independent mechanism mediates protection against steroid-induced senescence by resveralogues in equine tenocytes

PloS one, 2024-08, Vol.19 (8), p.e0309301

2024

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Drug discovery for ageing: SIMPs, NEDs and screening challenges

Nature reviews. Drug discovery, 2024-10, Vol.23 (10), p.725-726

2024

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Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2

Biogerontology (Dordrecht), 2016-04, Vol.17 (2), p.305-315

2016

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Resveralogues: From Novel Ageing Mechanisms to New Therapies?

Gerontology (Basel), 2020-05, Vol.66 (3), p.231-237

2020

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FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence

The FASEB journal, 2019-01, Vol.33 (1), p.1086-1097

2019

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Therapeutic Opportunities Presented by Modulation of Cellular Senescence

Biochemistry and Cell Biology of Ageing: Part III Biomedical Science, 2023, Vol.102, p.175-193

2023

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Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity

BioEssays, 2008-06, Vol.30 (6), p.567-578

2008

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Should we treat aging as a disease? The consequences and dangers of miscategorisation

Frontiers in genetics, 2015-07, Vol.6, p.171-171

Faragher, Richard G A

2015

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Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society

The journals of gerontology. Series A, Biological sciences and medical sciences, 2016-04, Vol.71 (4), p.435-444

2016

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Effects of resveratrol and its analogues on the cell cycle of equine mesenchymal stem/stromal cells

Journal of Equine Science, 2023, Vol.34(3), pp.67-72

2023

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Microarray analysis of senescent vascular smooth muscle cells: A link to atherosclerosis and vascular calcification

Experimental gerontology, 2009-10, Vol.44 (10), p.659-665

2009

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Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts

Biogerontology (Dordrecht), 2020-12, Vol.21 (6), p.817-826

2020

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Resveralogues protect HepG2 cells against cellular senescence induced by hepatotoxic metabolites

Mechanisms of ageing and development, 2024-06, Vol.219, p.111938-111938, Article 111938

2024

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Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform

Genes chromosomes & cancer, 2019-06, Vol.58 (6), p.341-356

2019

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Simple Detection Methods for Senescent Cells: Opportunities and Challenges

Frontiers in aging, 2021-07, Vol.2, p.686382-686382

Faragher, Richard G A

2021

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Linking interdisciplinary and multiscale approaches to improve healthspan—a new UK model for collaborative research networks in ageing biology and clinical translation

The Lancet. Healthy longevity, 2022-05, Vol.3 (5), p.e318-e320

2022

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The Biology of Ageing

Faragher, Richard

1, 2023

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Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts

Biogerontology (Dordrecht), 2020-12, Vol.21 (6), p.817-826

2020

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Absence of premature senescence in Werner's syndrome keratinocytes

Experimental gerontology, 2016-10, Vol.83, p.139-147

2016

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Senescence in the aging process [version 1; peer review: 3 approved]

F1000 research, 2017, Vol.6, p.1219-1219

2017

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Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

Nature genetics, 2000-01, Vol.24 (1), p.16-17

2000

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Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence

BMC cell biology, 2017-10, Vol.18 (1), p.31, Article 31

2017

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A facile, stereoselective, one-pot synthesis of resveratrol derivatives

BMC chemistry, 2015-05, Vol.9 (1), p.1, Article 26

2015

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The Biology of Ageing: From Hallmarks to Drugs

Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing

A SIRT1-independent mechanism mediates protection against steroid-induced senescence by resveralogues in equine tenocytes

Drug discovery for ageing: SIMPs, NEDs and screening challenges

Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2

Resveralogues: From Novel Ageing Mechanisms to New Therapies?

FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence

Therapeutic Opportunities Presented by Modulation of Cellular Senescence

Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity

Should we treat aging as a disease? The consequences and dangers of miscategorisation

Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society

Effects of resveratrol and its analogues on the cell cycle of equine mesenchymal stem/stromal cells

Microarray analysis of senescent vascular smooth muscle cells: A link to atherosclerosis and vascular calcification

Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts

Resveralogues protect HepG2 cells against cellular senescence induced by hepatotoxic metabolites

Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform

Simple Detection Methods for Senescent Cells: Opportunities and Challenges

Linking interdisciplinary and multiscale approaches to improve healthspan—a new UK model for collaborative research networks in ageing biology and clinical translation

The Biology of Ageing

Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts

Absence of premature senescence in Werner's syndrome keratinocytes

Senescence in the aging process [version 1; peer review: 3 approved]

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence

A facile, stereoselective, one-pot synthesis of resveratrol derivatives

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