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Discovery of Aryloxy Tetramethylcyclobutanes as Novel Androgen Receptor Antagonists

Journal of medicinal chemistry, 2011-11, Vol.54 (21), p.7693-7704

2011

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Discovery of 3-aryloxy-lactam analogs as potent androgen receptor full antagonists for treating castration resistant prostate cancer

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (2), p.1230-1236

2012

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Design of oxobenzimidazoles and oxindoles as novel androgen receptor antagonists

Bioorganic & medicinal chemistry letters, 2012-04, Vol.22 (7), p.2572-2578

2012

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N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11β-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (13), p.3493-3497

2009

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4-Hydroxyphenyl Retinamide Is a Highly Selective Activator of Retinoid Receptors

The Journal of biological chemistry, 1996-09, Vol.271 (37), p.22441-22446

1996

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Apoptosis induction and potent antiestrogen receptor-negative breast cancer activity in vivo by a retinoid antagonist

Cancer research (Chicago, Ill.), 1998-10, Vol.58 (20), p.4607-4610

1998

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Potential role for retinoic acid receptor-γ in the inhibition of breast cancer cells by selective retinoids and interferons

Cancer research (Chicago, Ill.), 1996-04, Vol.56 (7), p.1571-1577

1996

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N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (13), p.3493-3497

2009

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Cold-sensitive cytosolic 3,5,3'-triiodo-L-thyronine-binding protein and pyruvate kinase from human erythrocytes share similar regulatory properties of hormone binding by glycolytic intermediates

The Journal of biological chemistry, 1993-01, Vol.268 (1), p.175-179

1993

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4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptors

The Journal of biological chemistry, 1996-12, Vol.271 (52), p.33705-33705

1996

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Novel cold-sensitive cytosolic 3,5,3'-triiodo-L-thyronine-binding proteins in human red blood cell. Isolation and characterization

The Journal of biological chemistry, 1991-09, Vol.266 (25), p.16415-16419

1991

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Genome-wide CRISPR Screening to Identify Drivers of TGF-β-Induced Liver Fibrosis in Human Hepatic Stellate Cells

ACS chemical biology, 2022-04, Vol.17 (4), p.918-929

2022

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Novel retinoid-related molecules as apoptosis inducers and effective inhibitors of human lung cancer cells in vivo

Nature medicine, 1997-06, Vol.3 (6), p.686-690

1997

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A selective retinoid with high activity against an androgen‐resistant prostate cancer cell type

International journal of cancer, 1999-01, Vol.80 (2), p.272-278

1999

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Nuclear Retinoid Receptors and Their Mechanism of Action

Vitamins and Hormones, 1994, Vol.49, p.327-382

1994

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Discovery of Aryloxy Tetramethylcyclobutanes as Novel Androgen Receptor Antagonists

Discovery of 3-aryloxy-lactam analogs as potent androgen receptor full antagonists for treating castration resistant prostate cancer

Design of oxobenzimidazoles and oxindoles as novel androgen receptor antagonists

N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11β-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275

4-Hydroxyphenyl Retinamide Is a Highly Selective Activator of Retinoid Receptors

Apoptosis induction and potent antiestrogen receptor-negative breast cancer activity in vivo by a retinoid antagonist

Potential role for retinoic acid receptor-γ in the inhibition of breast cancer cells by selective retinoids and interferons

N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275

Cold-sensitive cytosolic 3,5,3'-triiodo-L-thyronine-binding protein and pyruvate kinase from human erythrocytes share similar regulatory properties of hormone binding by glycolytic intermediates

4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptors

Novel cold-sensitive cytosolic 3,5,3'-triiodo-L-thyronine-binding proteins in human red blood cell. Isolation and characterization

Genome-wide CRISPR Screening to Identify Drivers of TGF-β-Induced Liver Fibrosis in Human Hepatic Stellate Cells

Novel retinoid-related molecules as apoptosis inducers and effective inhibitors of human lung cancer cells in vivo

A selective retinoid with high activity against an androgen‐resistant prostate cancer cell type

Nuclear Retinoid Receptors and Their Mechanism of Action

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