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Aesculin suppresses the NLRP3 inflammasome-mediated pyroptosis via the Akt/GSK3β/NF-κB pathway to mitigate myocardial ischemia/reperfusion injury

Phytomedicine (Stuttgart), 2021-11, Vol.92, p.153687-153687, Article 153687

2021

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Immunity and inflammation in pulmonary arterial hypertension: From pathophysiology mechanisms to treatment perspective

Pharmacological research, 2022-06, Vol.180, p.106238-106238, Article 106238

2022

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RKC-B1 Blocks Activation of NF-κB and NLRP3 Signaling Pathways to Suppress Neuroinflammation in LPS-Stimulated Mice

Marine drugs, 2021-07, Vol.19 (8), p.429

2021

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Coptisine protects rat heart against myocardial ischemia/reperfusion injury by suppressing myocardial apoptosis and inflammation

Atherosclerosis, 2013-12, Vol.231 (2), p.384-391

2013

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Salvianolic acid A improve mitochondrial respiration and cardiac function via inhibiting apoptosis pathway through CRYAB in diabetic cardiomyopathy

Biomedicine & pharmacotherapy, 2023-04, Vol.160, p.114382-114382, Article 114382

2023

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Salvianolic acid A attenuates vascular remodeling in a pulmonary arterial hypertension rat model

Acta pharmacologica Sinica, 2016-06, Vol.37 (6), p.772-782

2016

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Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats

Atherosclerosis, 2012-05, Vol.222 (1), p.50-58

2012

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A novel hypertensive crisis rat model established by excessive norepinephrine infusion and the potential therapeutic effects of Rho-kinase inhibitors on it

Biomedicine & pharmacotherapy, 2019-01, Vol.109, p.1867-1875

2019

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Formononetin ameliorates myocardial ischemia/reperfusion injury in rats by suppressing the ROS-TXNIP-NLRP3 pathway

Biochemical and biophysical research communications, 2020-05, Vol.525 (3), p.759-766

2020

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Brazilin isolated from the heartwood of Caesalpinia sappan L induces endothelium-dependent and -independent relaxation of rat aortic rings

Acta pharmacologica Sinica, 2015-11, Vol.36 (11), p.1318-1326

2015

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DL0805-2, a novel indazole derivative, relaxes angiotensin II-induced contractions of rat aortic rings by inhibiting Rho kinase and calcium fluxes

Acta pharmacologica Sinica, 2016-05, Vol.37 (5), p.604-616

2016

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Advance in the study of myocardial ischemic preconditioning and postconditioning and the clinical applications

Yao hsüeh hsüeh pao, 2013-07, Vol.48 (7), p.965

2013

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Inhibitory effects of Brazilin on the vascular smooth muscle cell proliferation and migration induced by PDGF-BB

The American journal of Chinese medicine (1979), 2013, Vol.41 (6), p.1283

2013

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Syntheses and structure–activity relationships in cytotoxicities of 13-substituted quaternary coptisine derivatives

European journal of medicinal chemistry, 2014-10, Vol.86, p.542-549

2014

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Glucose consumption assay discovers coptisine with beneficial effect on diabetic mice

European journal of pharmacology, 2019-09, Vol.859, p.172523, Article 172523

2019

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Puerarin-V prevents the progression of hypoxia- and monocrotaline-induced pulmonary hypertension in rodent models

Acta pharmacologica Sinica, 2022-09, Vol.43 (9), p.2325-2339

2022

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Progress in study of pharmacological effect of Cortex Fraxini

Zhongguo zhongyao zazhi, 2008-12, Vol.33 (23), p.2732

2008

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Baicalein attenuates rotenone-induced SH-SY5Y cell apoptosis through binding to SUR1 and activating ATP-sensitive potassium channels

Acta pharmacologica Sinica, 2024-03, Vol.45 (3), p.480-489

2024

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Effect and mechanism of total flavonoids of bugloss on rats with myocardial ischemia and reperfusion injury

Yao hsüeh hsüeh pao, 2014-06, Vol.49 (6), p.875

2014

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Synthesis of quaternary 8-（1-acylethene-l-yl）-13-methylcoptisine chlorides and their selective growth inhibitory activity between human cancer cell lines and normal intestinal epithelial cell-6

中国化学快报：英文版, 2018, Vol.29 (1), p.131-135

2018

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Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1α/VEGF and FAK/AKT Signaling Pathways

Frontiers in pharmacology, 2022-03, Vol.13, p.844400-844400

2022

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Vasorelaxant effect of quercetin on cerebral basilar artery in vitro and the underlying mechanisms study

Journal of asian natural products research, 2018-05, Vol.20 (5), p.477-487

2018

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Endothelium-dependent and -independent relaxation induced by pinocembrin in rat aortic rings

Vascular pharmacology, 2007-03, Vol.46 (3), p.160-165

2007

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Fangchinoline inhibits rat aortic vascular smooth muscle cell proliferation and cell cycle progression through inhibition of ERK1/2 activation and c- fos expression

Biochemical pharmacology, 2003-11, Vol.66 (9), p.1853-1860

2003

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Synthesis and biological activity of flavanone derivatives

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (18), p.5466-5468

2010

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Aesculin suppresses the NLRP3 inflammasome-mediated pyroptosis via the Akt/GSK3β/NF-κB pathway to mitigate myocardial ischemia/reperfusion injury

Immunity and inflammation in pulmonary arterial hypertension: From pathophysiology mechanisms to treatment perspective

RKC-B1 Blocks Activation of NF-κB and NLRP3 Signaling Pathways to Suppress Neuroinflammation in LPS-Stimulated Mice

Coptisine protects rat heart against myocardial ischemia/reperfusion injury by suppressing myocardial apoptosis and inflammation

Salvianolic acid A improve mitochondrial respiration and cardiac function via inhibiting apoptosis pathway through CRYAB in diabetic cardiomyopathy

Salvianolic acid A attenuates vascular remodeling in a pulmonary arterial hypertension rat model

Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats

A novel hypertensive crisis rat model established by excessive norepinephrine infusion and the potential therapeutic effects of Rho-kinase inhibitors on it

Formononetin ameliorates myocardial ischemia/reperfusion injury in rats by suppressing the ROS-TXNIP-NLRP3 pathway

Brazilin isolated from the heartwood of Caesalpinia sappan L induces endothelium-dependent and -independent relaxation of rat aortic rings

DL0805-2, a novel indazole derivative, relaxes angiotensin II-induced contractions of rat aortic rings by inhibiting Rho kinase and calcium fluxes

Advance in the study of myocardial ischemic preconditioning and postconditioning and the clinical applications

Inhibitory effects of Brazilin on the vascular smooth muscle cell proliferation and migration induced by PDGF-BB

Syntheses and structure–activity relationships in cytotoxicities of 13-substituted quaternary coptisine derivatives

Glucose consumption assay discovers coptisine with beneficial effect on diabetic mice

Puerarin-V prevents the progression of hypoxia- and monocrotaline-induced pulmonary hypertension in rodent models

Progress in study of pharmacological effect of Cortex Fraxini

Baicalein attenuates rotenone-induced SH-SY5Y cell apoptosis through binding to SUR1 and activating ATP-sensitive potassium channels

Effect and mechanism of total flavonoids of bugloss on rats with myocardial ischemia and reperfusion injury

Synthesis of quaternary 8-（1-acylethene-l-yl）-13-methylcoptisine chlorides and their selective growth inhibitory activity between human cancer cell lines and normal intestinal epithelial cell-6

Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1α/VEGF and FAK/AKT Signaling Pathways

Vasorelaxant effect of quercetin on cerebral basilar artery in vitro and the underlying mechanisms study

Endothelium-dependent and -independent relaxation induced by pinocembrin in rat aortic rings

Fangchinoline inhibits rat aortic vascular smooth muscle cell proliferation and cell cycle progression through inhibition of ERK1/2 activation and c- fos expression

Synthesis and biological activity of flavanone derivatives

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