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Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

Nature cell biology, 2020-09, Vol.22 (9), p.1064-1075

2020

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Thymoquinone inhibits the metastasis of renal cell cancer cells by inducing autophagy via AMPK/mTOR signaling pathway

Cancer science, 2018-12, Vol.109 (12), p.3865-3873

2018

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Tetrandrine inhibits migration and invasion of human renal cell carcinoma by regulating Akt/NF-κB/MMP-9 signaling

PloS one, 2017-03, Vol.12 (3), p.e0173725-e0173725

2017

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MYC induces CDK4/6 inhibitors resistance by promoting pRB1 degradation

Nature communications, 2024-02, Vol.15 (1), p.1871-1871, Article 1871

2024

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TRABID overexpression enables synthetic lethality to PARP inhibitor via prolonging 53BP1 retention at double-strand breaks

Nature communications, 2023-03, Vol.14 (1), p.1810-1810, Article 1810

2023

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Deubiquitinase OTUD5 modulates mTORC1 signaling to promote bladder cancer progression

Cell death & disease, 2022-09, Vol.13 (9), p.778-778, Article 778

2022

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De Novo Design of an Androgen Receptor DNA Binding Domain‐Targeted peptide PROTAC for Prostate Cancer Therapy

Advanced science, 2022-10, Vol.9 (28), p.e2201859-n/a

2022

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Emerging role of ubiquitination/deubiquitination modification of PD-1/PD-L1 in cancer immunotherapy

Genes & diseases, 2023-05, Vol.10 (3), p.848-863

2023

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Development of a Double-Stapled Peptide Stabilizing Both α‑Helix and β‑Sheet Structures for Degrading Transcription Factor AR-V7

JACS Au, 2024-02, Vol.4 (2), p.816-827

2024

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β-ionone Inhibits Epithelial-Mesenchymal Transition (EMT) in Prostate Cancer Cells by Negatively Regulating the Wnt/β-Catenin Pathway

Frontiers in bioscience (Landmark. Print), 2022-12, Vol.27 (12), p.335-335

2022

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OTUD5-mediated deubiquitination of YAP in macrophage promotes M2 phenotype polarization and favors triple-negative breast cancer progression

Cancer letters, 2021-04, Vol.504, p.104-115

2021

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ERK1/2 inhibits Cullin 3/SPOP-mediated PrLZ ubiquitination and degradation to modulate prostate cancer progression

Cell death and differentiation, 2022-08, Vol.29 (8), p.1611-1624

2022

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Silibinin inhibits epithelial‑mesenchymal transition of renal cell carcinoma through autophagy‑dependent Wnt/β‑catenin signaling

International journal of molecular medicine, 2020-05, Vol.45 (5), p.1341-1350

2020

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Capsaicin inhibits the migration, invasion and EMT of renal cancer cells by inducing AMPK/mTOR-mediated autophagy

Chemico-biological interactions, 2022-10, Vol.366, p.110043-110043, Article 110043

2022

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Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer

Autophagy, 2021-12, Vol.17 (12), p.4386-4400

2021

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High-fat diet promotes liver tumorigenesis via palmitoylation and activation of AKT

Gut, 2024-07, Vol.73 (7), p.1156-1168

2024

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PD65-10 PRLZ INCREASES PROSTATE CANCER DOCETAXEL RESISTANCE BY INHIBITING LKB1/AMPK-MEDIATED AUTOPHAGY

The Journal of urology, 2018-04, Vol.199 (4), p.e1228-e1229

2018

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Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy

Molecular cell, 2023-10, Vol.83 (19), p.3520-3532.e7

2023

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Consecutive palmitoylation and phosphorylation orchestrates NLRP3 membrane trafficking and inflammasome activation

Molecular cell, 2024-09, Vol.84 (17), p.3336-3353.e7

2024

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A Top-Down Design Approach for Generating a Peptide PROTAC Drug Targeting Androgen Receptor for Androgenetic Alopecia Therapy

Journal of medicinal chemistry, 2024-06, Vol.67 (12), p.10336-10349

2024

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Chaperone-mediated autophagy in cancer: Advances from bench to bedside

Histology and histopathology, 2020-07, Vol.35 (7), p.637

2020

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Activation of PSGR with β-ionone suppresses prostate cancer progression by blocking androgen receptor nuclear translocation

Cancer letters, 2019-07, Vol.453, p.193-205

2019

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β‐Ionone represses renal cell carcinoma progression through activating LKB1/AMPK‐triggered autophagy

Journal of biochemical and molecular toxicology, 2023-06, Vol.37 (6), p.e23331-n/a

2023

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Silibinin inhibits the migration, invasion and epithelial-mesenchymal transition of prostate cancer by activating the autophagic degradation of YAP

Journal of Cancer, 2022-01, Vol.13 (13), p.3415-3426

2022

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Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy

EBioMedicine, 2024-07, Vol.105, p.105212, Article 105212

2024

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Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

Thymoquinone inhibits the metastasis of renal cell cancer cells by inducing autophagy via AMPK/mTOR signaling pathway

Tetrandrine inhibits migration and invasion of human renal cell carcinoma by regulating Akt/NF-κB/MMP-9 signaling

MYC induces CDK4/6 inhibitors resistance by promoting pRB1 degradation

TRABID overexpression enables synthetic lethality to PARP inhibitor via prolonging 53BP1 retention at double-strand breaks

Deubiquitinase OTUD5 modulates mTORC1 signaling to promote bladder cancer progression

De Novo Design of an Androgen Receptor DNA Binding Domain‐Targeted peptide PROTAC for Prostate Cancer Therapy

Emerging role of ubiquitination/deubiquitination modification of PD-1/PD-L1 in cancer immunotherapy

Development of a Double-Stapled Peptide Stabilizing Both α‑Helix and β‑Sheet Structures for Degrading Transcription Factor AR-V7

β-ionone Inhibits Epithelial-Mesenchymal Transition (EMT) in Prostate Cancer Cells by Negatively Regulating the Wnt/β-Catenin Pathway

OTUD5-mediated deubiquitination of YAP in macrophage promotes M2 phenotype polarization and favors triple-negative breast cancer progression

ERK1/2 inhibits Cullin 3/SPOP-mediated PrLZ ubiquitination and degradation to modulate prostate cancer progression

Silibinin inhibits epithelial‑mesenchymal transition of renal cell carcinoma through autophagy‑dependent Wnt/β‑catenin signaling

Capsaicin inhibits the migration, invasion and EMT of renal cancer cells by inducing AMPK/mTOR-mediated autophagy

Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer

High-fat diet promotes liver tumorigenesis via palmitoylation and activation of AKT

PD65-10 PRLZ INCREASES PROSTATE CANCER DOCETAXEL RESISTANCE BY INHIBITING LKB1/AMPK-MEDIATED AUTOPHAGY

Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy

Consecutive palmitoylation and phosphorylation orchestrates NLRP3 membrane trafficking and inflammasome activation

A Top-Down Design Approach for Generating a Peptide PROTAC Drug Targeting Androgen Receptor for Androgenetic Alopecia Therapy

Chaperone-mediated autophagy in cancer: Advances from bench to bedside

Activation of PSGR with β-ionone suppresses prostate cancer progression by blocking androgen receptor nuclear translocation

β‐Ionone represses renal cell carcinoma progression through activating LKB1/AMPK‐triggered autophagy

Silibinin inhibits the migration, invasion and epithelial-mesenchymal transition of prostate cancer by activating the autophagic degradation of YAP

Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy

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