UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 206

Sortiert nach

Physiologically Based Pharmacokinetic Modeling of Nanoparticles

Journal of pharmaceutical sciences, 2019-01, Vol.108 (1), p.58-72

2019

Volltextzugriff (PDF)

A Multiscale Physiologically-Based Pharmacokinetic Model for Doxorubicin to Explore its Mechanisms of Cytotoxicity and Cardiotoxicity in Human Physiological Contexts

Pharmaceutical research, 2018-09, Vol.35 (9), p.174-10, Article 174

2018

Volltextzugriff (PDF)

Usage of In Vitro Metabolism Data for Drug‐Drug Interaction in Physiologically Based Pharmacokinetic Analysis Submissions to the US Food and Drug Administration

Journal of clinical pharmacology, 2021-06, Vol.61 (6), p.782-788

2021

Volltextzugriff (PDF)

Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs

Molecular pharmaceutics, 2017-12, Vol.14 (12), p.4281-4294

2017

Volltextzugriff (PDF)

Nicotine aggravates vascular adiponectin resistance via ubiquitin-mediated adiponectin receptor degradation in diabetic Apolipoprotein E knockout mouse

Cell death & disease, 2021-05, Vol.12 (6), p.508-508, Article 508

2021

Volltextzugriff (PDF)

Vitamin D Receptor Activation Down-regulates the Small Heterodimer Partner and Increases CYP7A1 to Lower Cholesterol

Gastroenterology (New York, N.Y. 1943), 2014-04, Vol.146 (4), p.1048-1059.e7

2014

Volltextzugriff (PDF)

Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach

European journal of pharmaceutics and biopharmaceutics, 2018-08, Vol.129, p.162-174

2018

Volltextzugriff (PDF)

Regulatory utility of physiologically‐based pharmacokinetic modeling to support alternative bioequivalence approaches and risk assessment: A workshop summary report

CPT: pharmacometrics and systems pharmacology, 2023-05, Vol.12 (5), p.585-597

2023

Volltextzugriff (PDF)

Anti–SARS‐CoV‐2 Repurposing Drug Database: Clinical Pharmacology Considerations

CPT: pharmacometrics and systems pharmacology, 2021-09, Vol.10 (9), p.973-982

2021

Volltextzugriff (PDF)

PBPK modeling of intestinal and liver enzymes and transporters in drug absorption and sequential metabolism

Current drug metabolism, 2010-11, Vol.11 (9), p.743

2010

Volltextzugriff (PDF)

Pharmacokinetics

Biochemical pharmacology, 2014-01, Vol.87 (1), p.93-120

2014

Volltextzugriff (PDF)

Bone morphogenetic protein-4 induced Rat hepatic progenitor cell (WB-F344 cell) differentiation toward hepatocyte lineage

Journal of cellular physiology, 2009-07, Vol.220 (1), p.72-81

2009

Volltextzugriff (PDF)

Connecting Hydroxychloroquine In Vitro Antiviral Activity to In Vivo Concentration for Prediction of Antiviral Effect: A Critical Step in Treating Patients With Coronavirus Disease 2019

Clinical infectious diseases, 2020-12, Vol.71 (12), p.3232-3236

2020

Volltextzugriff (PDF)

Application of PBPK Modeling and Simulation for Regulatory Decision Making and Its Impact on US Prescribing Information: An Update on the 2018‐2019 Submissions to the US FDA's Office of Clinical Pharmacology

Journal of clinical pharmacology, 2020-10, Vol.60 (S1 Suppl 1), p.S160-S178

2020

Volltextzugriff (PDF)

Utility of Physiologically Based Pharmacokinetic Absorption Modeling to Predict the Impact of Salt-to-Base Conversion on Prasugrel HCl Product Bioequivalence in the Presence of Proton Pump Inhibitors

The AAPS journal, 2017-09, Vol.19 (5), p.1479-1486

2017

Volltextzugriff (PDF)

Computational Model of In Vivo Corneal Pharmacokinetics and Pharmacodynamics of Topically Administered Ophthalmic Drug Products

Pharmaceutical research, 2023-04, Vol.40 (4), p.961-975

2023

Volltextzugriff (PDF)

Mathematical modeling of the heterogeneous distributions of nanomedicines in solid tumors

European journal of pharmaceutics and biopharmaceutics, 2019-09, Vol.142, p.153-164

2019

Volltextzugriff (PDF)

Whole Body PBPK Modeling of Remdesivir and Its Metabolites to Aid in Estimating Active Metabolite Exposure in the Lung and Liver in Patients With Organ Dysfunction

Clinical pharmacology and therapeutics, 2022-03, Vol.111 (3), p.624-634

2022

Volltextzugriff (PDF)

Model‐Informed Drug Development Approaches to Assist New Drug Development in the COVID‐19 Pandemic

Clinical pharmacology and therapeutics, 2022-03, Vol.111 (3), p.572-578

2022

Volltextzugriff (PDF)

FDA Approval Summary: Selumetinib for Plexiform Neurofibroma

Clinical cancer research, 2021-08, Vol.27 (15), p.4142-4146

2021

Volltextzugriff (PDF)

FDA Approval Summary: Tucatinib for the Treatment of Patients with Advanced or Metastatic HER2-positive Breast Cancer

Clinical cancer research, 2021-03, Vol.27 (5), p.1220-1226

2021

Volltextzugriff (PDF)

Using Physiologically Based Pharmacokinetic (PBPK) Modeling to Evaluate the Impact of Pharmaceutical Excipients on Oral Drug Absorption: Sensitivity Analyses

The AAPS journal, 2016-11, Vol.18 (6), p.1500-1511

2016

Volltextzugriff (PDF)

Protocol for evaluation of topical ophthalmic drug products in different compartments of fresh eye tissues in a rabbit model

Journal of pharmacological and toxicological methods, 2019-03, Vol.96, p.9-14

2019

Volltextzugriff (PDF)

Cloning and promoter activity of rat Smad1 5'-flanking region in rat hepatic stellate cells

Molecular and cellular biochemistry, 2007-10, Vol.304 (1-2), p.227-234

2007

Volltextzugriff (PDF)

1 – 25 von 206

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(172)
Mit Volltextzugriff
(181)

Publikationsform

Sprache

Erscheinungsjahr

n.n

Thema

Science & Technology
(142)
Life Sciences & Biomedicine
(89)
Humans
(52)
Technology
(52)
Engineering
(40)
Animals
(39)
Pharmacology & Pharmacy
(27)
Male
(23)
Engineering, Electrical & Electronic
(22)
Physical Sciences
(20)
Materials Science
(18)
Female
(17)
Mice
(17)
Materials Science, Multidisciplinary
(16)
Models, Biological
(15)
Chemistry
(14)
Computer Science
(13)
Telecommunications
(13)
Adult
(12)
Rats
(12)

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(1)
... seit 90 Tagen
(3)

Menü

Weitere Dienste

Einstellungen

Physiologically Based Pharmacokinetic Modeling of Nanoparticles

A Multiscale Physiologically-Based Pharmacokinetic Model for Doxorubicin to Explore its Mechanisms of Cytotoxicity and Cardiotoxicity in Human Physiological Contexts

Usage of In Vitro Metabolism Data for Drug‐Drug Interaction in Physiologically Based Pharmacokinetic Analysis Submissions to the US Food and Drug Administration

Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs

Nicotine aggravates vascular adiponectin resistance via ubiquitin-mediated adiponectin receptor degradation in diabetic Apolipoprotein E knockout mouse

Vitamin D Receptor Activation Down-regulates the Small Heterodimer Partner and Increases CYP7A1 to Lower Cholesterol

Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach

Regulatory utility of physiologically‐based pharmacokinetic modeling to support alternative bioequivalence approaches and risk assessment: A workshop summary report

Anti–SARS‐CoV‐2 Repurposing Drug Database: Clinical Pharmacology Considerations

PBPK modeling of intestinal and liver enzymes and transporters in drug absorption and sequential metabolism

Pharmacokinetics

Bone morphogenetic protein-4 induced Rat hepatic progenitor cell (WB-F344 cell) differentiation toward hepatocyte lineage

Connecting Hydroxychloroquine In Vitro Antiviral Activity to In Vivo Concentration for Prediction of Antiviral Effect: A Critical Step in Treating Patients With Coronavirus Disease 2019

Application of PBPK Modeling and Simulation for Regulatory Decision Making and Its Impact on US Prescribing Information: An Update on the 2018‐2019 Submissions to the US FDA's Office of Clinical Pharmacology

Utility of Physiologically Based Pharmacokinetic Absorption Modeling to Predict the Impact of Salt-to-Base Conversion on Prasugrel HCl Product Bioequivalence in the Presence of Proton Pump Inhibitors

Computational Model of In Vivo Corneal Pharmacokinetics and Pharmacodynamics of Topically Administered Ophthalmic Drug Products

Mathematical modeling of the heterogeneous distributions of nanomedicines in solid tumors

Whole Body PBPK Modeling of Remdesivir and Its Metabolites to Aid in Estimating Active Metabolite Exposure in the Lung and Liver in Patients With Organ Dysfunction

FDA Approval Summary: Alpelisib Plus Fulvestrant for Patients with HR-positive, HER2-negative, PIK3CA-mutated, Advanced or Metastatic Breast Cancer

Model‐Informed Drug Development Approaches to Assist New Drug Development in the COVID‐19 Pandemic

FDA Approval Summary: Selumetinib for Plexiform Neurofibroma

FDA Approval Summary: Tucatinib for the Treatment of Patients with Advanced or Metastatic HER2-positive Breast Cancer

Using Physiologically Based Pharmacokinetic (PBPK) Modeling to Evaluate the Impact of Pharmaceutical Excipients on Oral Drug Absorption: Sensitivity Analyses

Protocol for evaluation of topical ophthalmic drug products in different compartments of fresh eye tissues in a rabbit model

Cloning and promoter activity of rat Smad1 5'-flanking region in rat hepatic stellate cells

Suchergebnisse filtern