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Molecular mechanism of heavy metals (Lead, Chromium, Arsenic, Mercury, Nickel and Cadmium) - induced hepatotoxicity – A review

Chemosphere (Oxford), 2021-05, Vol.271, p.129735, Article 129735

2021

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Natural Bioactive Compounds and Human Health

Molecules (Basel, Switzerland), 2024-07, Vol.29 (14), p.3372

2024

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Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation

Biomedicine & pharmacotherapy, 2022-05, Vol.149, p.112914-112914, Article 112914

2022

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Antimicrobial and Larvicidal Activities of Different Ocimum Essential Oils Extracted by Ultrasound-Assisted Hydrodistillation

Molecules (Basel, Switzerland), 2022-02, Vol.27 (5), p.1456

2022

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Hesperidin protects against cadmium-induced pancreatitis by modulating insulin secretion, redox imbalance and iNOS/NF-ĸB signaling in rats

Life sciences (1973), 2020-10, Vol.259, p.118268-118268, Article 118268

2020

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Oxyresveratrol-β-cyclodextrin mitigates streptozotocin-induced Alzheimer's model cognitive impairment, histone deacetylase activity in rats: in silico & in vivo studies

Scientific reports, 2024-04, Vol.14 (1), p.9897-9897, Article 9897

2024

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Virgin coconut oil supplementation attenuates acute chemotherapy hepatotoxicity induced by anticancer drug methotrexate via inhibition of oxidative stress in rats

Biomedicine & pharmacotherapy, 2017-03, Vol.87, p.437-442

2017

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The Therapeutic Mechanisms of Honey in Mitigating Toxicity from Anticancer Chemotherapy Toxicity: A Review

Journal of xenobiotics, 2024-09, Vol.14 (3), p.1109-1129

2024

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Epigenetic Alterations in Alzheimer's Disease: Impact on Insulin Signaling and Advanced Drug Delivery Systems

Biology (Basel, Switzerland), 2024-02, Vol.13 (3), p.157

2024

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Geraniol prevents CCl4-induced hepatotoxicity via suppression of hepatic oxidative stress, pro-inflammation and apoptosis in rats

Toxicology reports, 2024-06, Vol.12, p.128-134

2024

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Synergistic Action of Virgin Coconut Oil and Clomiphene in Reversing Endocrine Dysregulation in Letrozole-Model of Polycystic Ovarian Syndrome in Rats: Role of Nrf2/HMOX-1 Pathway

Journal of medicinal food, 2023-09, Vol.26 (9), p.683-691

2023

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Chemical Composition and Biological Activities of the Leaf Essential Oils of Curcuma longa, Curcuma aromatica and Curcuma angustifolia

Antibiotics (Basel), 2022-11, Vol.11 (11), p.1547

2022

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Thymoquinone Abrogates Acrylamide-Induced Cerebellar Toxicity via Modulation of Nuclear Factor Erythroid 2-Related Factor 2/Nuclear Factor Kappa B Signaling, Oxidative Neuroinflammation, and Neuroapoptosis in Rats

Journal of medicinal food, 2024-09

2024

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Hyperoside attenuates neuroinflammation, cognitive impairment and oxidative stress via suppressing TNF-α/NF-κB/caspase-3 signaling in type 2 diabetes rats

Nutritional neuroscience, 2022-08, Vol.25 (8), p.1774-1784

2022

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Anti-ischemic drug trimetazidine blocks mercury nephrotoxicity by suppressing renal redox imbalance, inflammatory stress and caspase-dependent apoptosis in rats

Drug and chemical toxicology (New York, N.Y. 1978), 2024-09, Vol.47 (5), p.674-681

2024

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Beneficial role of virgin coconut oil supplementation against acute methotrexate chemotherapy-induced oxidative toxicity and inflammation in rats

Integrative Medicine Research, 2018, 7(3), 24, pp.257-263

2018

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Cytotoxic Activity of Herbal Medicines as Assessed in Vitro: A Review

Chemistry & biodiversity, 2023-02, Vol.20 (2), p.e202201098-n/a

2023

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Repurposing FDA-approved drugs against the toxicity of platinum-based anticancer drugs

Life sciences (1973), 2022-09, Vol.305, p.120789-120789, Article 120789

2022

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Antidiabetic drug sitagliptin blocks cyclophosphamide cerebral neurotoxicity by activating Nrf2 and suppressing redox cycle imbalance, inflammatory iNOS/NO/NF-κB response and caspase-3/Bax activation in rats

International immunopharmacology, 2023-03, Vol.116, p.109816-109816, Article 109816

2023

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Effect of parboiling on toxic metal content and nutritional composition of three rice varieties locally produced in Nigeria

Scientific African, 2020-11, Vol.10, p.e00580, Article e00580

2020

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Naringin ameliorates 5-fluorouracil induced cardiotoxicity: An insight into its modulatory impact on oxidative stress, inflammatory and apoptotic parameters

Tissue & cell, 2023-04, Vol.81, p.102035-102035, Article 102035

2023

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Molecular mechanisms underpinning the protection against antiretroviral drug-induced sperm-endocrine aberrations and testicular toxicity: A review

Reproductive toxicology (Elmsford, N.Y.), 2024-09, Vol.128, p.108629, Article 108629

2024

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Naringenin blocks hepatic cadmium accumulation and suppresses cadmium-induced hepatotoxicity via amelioration of oxidative inflammatory signaling and apoptosis in rats

Drug and chemical toxicology (New York, N.Y. 1978), 2024-07, Vol.ahead-of-print (ahead-of-print), p.1-9

2024

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Association of Blood and Seminal Plasma Cadmium and Lead Levels With Semen Quality in Non-Occupationally Exposed Infertile Men in Abakaliki, South East Nigeria

Journal of family & reproductive health, 2017-06, Vol.11 (2), p.97-103

2017

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Protective Effects of Nucleosides‐Rich Extract from Cordyceps cicadae against Cisplatin Induced Testicular Damage

Chemistry & biodiversity, 2020-11, Vol.17 (11), p.e2000671-n/a

2020

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Molecular mechanism of heavy metals (Lead, Chromium, Arsenic, Mercury, Nickel and Cadmium) - induced hepatotoxicity – A review

Natural Bioactive Compounds and Human Health

Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation

Antimicrobial and Larvicidal Activities of Different Ocimum Essential Oils Extracted by Ultrasound-Assisted Hydrodistillation

Hesperidin protects against cadmium-induced pancreatitis by modulating insulin secretion, redox imbalance and iNOS/NF-ĸB signaling in rats

Oxyresveratrol-β-cyclodextrin mitigates streptozotocin-induced Alzheimer's model cognitive impairment, histone deacetylase activity in rats: in silico & in vivo studies

Virgin coconut oil supplementation attenuates acute chemotherapy hepatotoxicity induced by anticancer drug methotrexate via inhibition of oxidative stress in rats

The Therapeutic Mechanisms of Honey in Mitigating Toxicity from Anticancer Chemotherapy Toxicity: A Review

Epigenetic Alterations in Alzheimer's Disease: Impact on Insulin Signaling and Advanced Drug Delivery Systems

Geraniol prevents CCl4-induced hepatotoxicity via suppression of hepatic oxidative stress, pro-inflammation and apoptosis in rats

Synergistic Action of Virgin Coconut Oil and Clomiphene in Reversing Endocrine Dysregulation in Letrozole-Model of Polycystic Ovarian Syndrome in Rats: Role of Nrf2/HMOX-1 Pathway

Chemical Composition and Biological Activities of the Leaf Essential Oils of Curcuma longa, Curcuma aromatica and Curcuma angustifolia

Thymoquinone Abrogates Acrylamide-Induced Cerebellar Toxicity via Modulation of Nuclear Factor Erythroid 2-Related Factor 2/Nuclear Factor Kappa B Signaling, Oxidative Neuroinflammation, and Neuroapoptosis in Rats

Hyperoside attenuates neuroinflammation, cognitive impairment and oxidative stress via suppressing TNF-α/NF-κB/caspase-3 signaling in type 2 diabetes rats

Anti-ischemic drug trimetazidine blocks mercury nephrotoxicity by suppressing renal redox imbalance, inflammatory stress and caspase-dependent apoptosis in rats

Beneficial role of virgin coconut oil supplementation against acute methotrexate chemotherapy-induced oxidative toxicity and inflammation in rats

Cytotoxic Activity of Herbal Medicines as Assessed in Vitro: A Review

Repurposing FDA-approved drugs against the toxicity of platinum-based anticancer drugs

Antidiabetic drug sitagliptin blocks cyclophosphamide cerebral neurotoxicity by activating Nrf2 and suppressing redox cycle imbalance, inflammatory iNOS/NO/NF-κB response and caspase-3/Bax activation in rats

Effect of parboiling on toxic metal content and nutritional composition of three rice varieties locally produced in Nigeria

Naringin ameliorates 5-fluorouracil induced cardiotoxicity: An insight into its modulatory impact on oxidative stress, inflammatory and apoptotic parameters

Molecular mechanisms underpinning the protection against antiretroviral drug-induced sperm-endocrine aberrations and testicular toxicity: A review

Naringenin blocks hepatic cadmium accumulation and suppresses cadmium-induced hepatotoxicity via amelioration of oxidative inflammatory signaling and apoptosis in rats

Association of Blood and Seminal Plasma Cadmium and Lead Levels With Semen Quality in Non-Occupationally Exposed Infertile Men in Abakaliki, South East Nigeria

Protective Effects of Nucleosides‐Rich Extract from Cordyceps cicadae against Cisplatin Induced Testicular Damage

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