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Maintenance and Expression of Mammalian Mitochondrial DNA

Annual review of biochemistry, 2016-06, Vol.85 (1), p.133-160

2016

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TWINKLE and Other Human Mitochondrial DNA Helicases: Structure, Function and Disease

Genes, 2020-04, Vol.11 (4), p.408

2020

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Organization of DNA in Mammalian Mitochondria

International journal of molecular sciences, 2019-06, Vol.20 (11), p.2770

2019

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Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (33), p.13534-13539

2011

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Selective mitochondrial DNA degradation following double-strand breaks

PloS one, 2017-04, Vol.12 (4), p.e0176795-e0176795

2017

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The human mitochondrial replication fork in health and disease

Biochimica et biophysica acta, 2010-08, Vol.1797 (8), p.1378-1388

2010

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Mitochondrial DNA replication in mammalian cells: overview of the pathway

Essays in biochemistry, 2018-07, Vol.62 (3), p.287-296

2018

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Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (36), p.11288-11293

2015

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DNA replication and transcription in mammalian mitochondria

Annual review of biochemistry, 2007-01, Vol.76 (1), p.679-699

2007

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Small-molecule inhibitors of human mitochondrial DNA transcription

Nature (London), 2020-12, Vol.588 (7839), p.712-716

2020

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RNase H1 directs origin-specific initiation of DNA replication in human mitochondria

PLoS genetics, 2019-01, Vol.15 (1), p.e1007781-e1007781

2019

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In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication

PLoS genetics, 2014-12, Vol.10 (12), p.e1004832-e1004832

2014

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Mammalian transcription factor A is a core component of the mitochondrial transcription machinery

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (41), p.16510-16515

2012

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Regulation of DNA replication at the end of the mitochondrial D-loop involves the helicase TWINKLE and a conserved sequence element

Nucleic acids research, 2015-10, Vol.43 (19), p.9262-9275

2015

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Accurate mapping of mitochondrial DNA deletions and duplications using deep sequencing

PLoS genetics, 2020-12, Vol.16 (12), p.e1009242

2020

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G-quadruplex structures in RNA stimulate mitochondrial transcription termination and primer formation

Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (37), p.16072-16077

2010

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Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (43), p.18231-18236

2009

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Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA

PLoS genetics, 2017-02, Vol.13 (2), p.e1006628-e1006628

2017

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Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria

Nature communications, 2018-03, Vol.9 (1), p.1202-13, Article 1202

2018

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Defective mitochondrial protease LonP1 can cause classical mitochondrial disease

Human molecular genetics, 2018-05, Vol.27 (10), p.1743-1753

2018

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Reconstitution of a minimal mtDNA replisome in vitro

The EMBO journal, 2004-06, Vol.23 (12), p.2423-2429

2004

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A two-nuclease pathway involving RNase H1 is required for primer removal at human mitochondrial OriL

Nucleic acids research, 2018-10, Vol.46 (18), p.9471-9483

2018

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Mitochondrial RNA Polymerase Is Needed for Activation of the Origin of Light-Strand DNA Replication

Molecular cell, 2010-01, Vol.37 (1), p.67-78

2010

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Copy-choice recombination during mitochondrial L-strand synthesis causes DNA deletions

Nature communications, 2019-02, Vol.10 (1), p.759-10, Article 759

2019

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TWINKLE Has 5′ → 3′ DNA Helicase Activity and Is Specifically Stimulated by Mitochondrial Single-stranded DNA-binding Protein

The Journal of biological chemistry, 2003-12, Vol.278 (49), p.48627-48632

2003

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Maintenance and Expression of Mammalian Mitochondrial DNA

TWINKLE and Other Human Mitochondrial DNA Helicases: Structure, Function and Disease

Organization of DNA in Mammalian Mitochondria

Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA

Selective mitochondrial DNA degradation following double-strand breaks

The human mitochondrial replication fork in health and disease

Mitochondrial DNA replication in mammalian cells: overview of the pathway

Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid

DNA replication and transcription in mammalian mitochondria

Small-molecule inhibitors of human mitochondrial DNA transcription

RNase H1 directs origin-specific initiation of DNA replication in human mitochondria

In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication

Mammalian transcription factor A is a core component of the mitochondrial transcription machinery

Regulation of DNA replication at the end of the mitochondrial D-loop involves the helicase TWINKLE and a conserved sequence element

Accurate mapping of mitochondrial DNA deletions and duplications using deep sequencing

G-quadruplex structures in RNA stimulate mitochondrial transcription termination and primer formation

Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging

Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria

Defective mitochondrial protease LonP1 can cause classical mitochondrial disease

Reconstitution of a minimal mtDNA replisome in vitro

A two-nuclease pathway involving RNase H1 is required for primer removal at human mitochondrial OriL

Mitochondrial RNA Polymerase Is Needed for Activation of the Origin of Light-Strand DNA Replication

Copy-choice recombination during mitochondrial L-strand synthesis causes DNA deletions

TWINKLE Has 5′ → 3′ DNA Helicase Activity and Is Specifically Stimulated by Mitochondrial Single-stranded DNA-binding Protein

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