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Evidence of CNIH3 involvement in opioid dependence

Molecular psychiatry, 2016-05, Vol.21 (5), p.608-614

2016

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In vivo activation of the SK channel in the spinal cord reduces the NMDA receptor antagonist dose needed to produce antinociception in an inflammatory pain model

Pain (Amsterdam), 2015-05, Vol.156 (5), p.849-858

2015

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The Contribution of the Descending Pain Modulatory Pathway in Opioid Tolerance

Frontiers in neuroscience, 2018-11, Vol.12, p.886-886

2018

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Rescue of Learning and Memory Deficits in the Human Nonsyndromic Intellectual Disability Cereblon Knock-Out Mouse Model by Targeting the AMP-Activated Protein Kinase-mTORC1 Translational Pathway

The Journal of neuroscience, 2018-03, Vol.38 (11), p.2780-2795

2018

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Novel Application for G Protein-Biased Mu Opioid Receptor Agonists in Opioid Relapse Prevention

Biological psychiatry (1969), 2020-12, Vol.88 (12), p.896-897

2020

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PEN Receptor GPR83 in Anxiety-Like Behaviors: Differential Regulation in Global vs Amygdalar Knockdown

Frontiers in neuroscience, 2021-08, Vol.15, p.675769-675769

2021

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GPR83 engages endogenous peptides from two distinct precursors to elicit differential signaling

Molecular pharmacology, 2022-07, Vol.102 (1), p.29-38

2022

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Multiomics Analyses Identify Proline Endopeptidase-Like Protein As a Key Regulator of Protein Trafficking, a Pathway Underlying Alzheimer's Disease Pathogenesis

Molecular pharmacology, 2023-07, Vol.104 (1), p.1-16

2023

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Neuropeptidomic Analysis of a Genetically Defined Cell Type in Mouse Brain and Pituitary

Cell chemical biology, 2021-01, Vol.28 (1), p.105-112.e4

2021

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Mice heterozygous for a null mutation of CPE show reduced expression of carboxypeptidase e mRNA and enzyme activity but normal physiology, behavior, and levels of neuropeptides

Brain research, 2022-08, Vol.1789, p.147951-147951, Article 147951

2022

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Morphine-Associated Contextual Cues Induce Structural Plasticity in Hippocampal CA1 Pyramidal Neurons

Neuropsychopharmacology (New York, N.Y.), 2016-10, Vol.41 (11), p.2668-2678

2016

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Targeting the Recently Deorphanized Receptor GPR83 for the Treatment of Immunological, Neuroendocrine and Neuropsychiatric Disorders

Progress in molecular biology and translational science, 2018, Vol.159, p.1-25

2018

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Increased Small Conductance Calcium-Activated Potassium Type 2 Channel-Mediated Negative Feedback on N -methyl-D-aspartate Receptors Impairs Synaptic Plasticity Following Context-Dependent Sensitization to Morphine

Biological psychiatry (1969), 2014-01, Vol.75 (2), p.105-114

2014

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Identification of GPR83 as the receptor for the neuroendocrine peptide PEN

Science signaling, 2016-04, Vol.9 (425), p.ra43

2016

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Hippocampal long-term potentiation is disrupted during expression and extinction but is restored after reinstatement of morphine place preference

The Journal of neuroscience, 2014-01, Vol.34 (2), p.527-538

2014

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The role of the neuropeptide PEN receptor, GPR83, in the reward pathway: Relationship to sex-differences

Neuropharmacology, 2019-10, Vol.157, p.107666-107666, Article 107666

2019

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Collybolide is a novel biased agonist of κ-opioid receptors with potent antipruritic activity

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (21), p.6041-6046

2016

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Hippocampal GluA1-containing AMPA receptors mediate context-dependent sensitization to morphine

The Journal of neuroscience, 2011-11, Vol.31 (45), p.16279-16291

2011

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Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease

Nature communications, 2020-08, Vol.11 (1), p.3942-19, Article 3942

2020

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Fasting enhances the response of arcuate neuropeptide Y-glucose-inhibited neurons to decreased extracellular glucose

American Journal of Physiology: Cell Physiology, 2009-04, Vol.296 (4), p.C746-C756

2009

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Purkinje cell dysfunction and delayed death in plasma membrane calcium ATPase 2-heterozygous mice

Molecular and cellular neuroscience, 2012-08, Vol.51 (1-2), p.22-31

2012

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Collybolide is a novel biased agonist of ?-opioid receptors with potent antipruritic activity

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (21), p.6041

2016

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Increased SK2 channel-mediated negative feedback on NMDAR impairs synaptic plasticity following context-dependent sensitization to morphine

Biological psychiatry (1969), 2013-06, Vol.75 (2), p.105-114

2013

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Evidence of CNIH3 involvement in opioid dependence

In vivo activation of the SK channel in the spinal cord reduces the NMDA receptor antagonist dose needed to produce antinociception in an inflammatory pain model

The Contribution of the Descending Pain Modulatory Pathway in Opioid Tolerance

Rescue of Learning and Memory Deficits in the Human Nonsyndromic Intellectual Disability Cereblon Knock-Out Mouse Model by Targeting the AMP-Activated Protein Kinase-mTORC1 Translational Pathway

Novel Application for G Protein-Biased Mu Opioid Receptor Agonists in Opioid Relapse Prevention

PEN Receptor GPR83 in Anxiety-Like Behaviors: Differential Regulation in Global vs Amygdalar Knockdown

GPR83 engages endogenous peptides from two distinct precursors to elicit differential signaling

Multiomics Analyses Identify Proline Endopeptidase-Like Protein As a Key Regulator of Protein Trafficking, a Pathway Underlying Alzheimer's Disease Pathogenesis

Neuropeptidomic Analysis of a Genetically Defined Cell Type in Mouse Brain and Pituitary

Mice heterozygous for a null mutation of CPE show reduced expression of carboxypeptidase e mRNA and enzyme activity but normal physiology, behavior, and levels of neuropeptides

Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia

Morphine-Associated Contextual Cues Induce Structural Plasticity in Hippocampal CA1 Pyramidal Neurons

Targeting the Recently Deorphanized Receptor GPR83 for the Treatment of Immunological, Neuroendocrine and Neuropsychiatric Disorders

Increased Small Conductance Calcium-Activated Potassium Type 2 Channel-Mediated Negative Feedback on N -methyl-D-aspartate Receptors Impairs Synaptic Plasticity Following Context-Dependent Sensitization to Morphine

Identification of GPR83 as the receptor for the neuroendocrine peptide PEN

Hippocampal long-term potentiation is disrupted during expression and extinction but is restored after reinstatement of morphine place preference

The role of the neuropeptide PEN receptor, GPR83, in the reward pathway: Relationship to sex-differences

Collybolide is a novel biased agonist of κ-opioid receptors with potent antipruritic activity

Hippocampal GluA1-containing AMPA receptors mediate context-dependent sensitization to morphine

Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease

Fasting enhances the response of arcuate neuropeptide Y-glucose-inhibited neurons to decreased extracellular glucose

Purkinje cell dysfunction and delayed death in plasma membrane calcium ATPase 2-heterozygous mice

Collybolide is a novel biased agonist of ?-opioid receptors with potent antipruritic activity

Increased SK2 channel-mediated negative feedback on NMDAR impairs synaptic plasticity following context-dependent sensitization to morphine

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