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The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia

Leukemia, 2009-11, Vol.23 (11), p.2034-2041

2009

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MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activation

Journal of leukocyte biology, 1999-01, Vol.65 (1), p.2-5

1999

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Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family

Cell death and differentiation, 2007-09, Vol.14 (9), p.1711-1713

2007

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Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands

Cell death and differentiation, 2008-10, Vol.15 (10), p.1564-1571

2008

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Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays

Cell death & disease, 2012-03, Vol.3 (3), p.e288-e288

2012

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Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax

Cell death & disease, 2015-04, Vol.6 (4), p.e1735-e1735

2015

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The transforming growth factor-β superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women

The journal of clinical endocrinology and metabolism, 2000-12, Vol.85 (12), p.4781-4788

2000

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Antibody-Based Approach to High-Volume Genotyping for MIC-1 Polymorphism

BioTechniques, 2002-07, Vol.33 (1), p.118-126

2002

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BCL-XL is an actionable target for treatment of malignant pleural mesothelioma

Cell death discovery, 2020-10, Vol.6 (1), p.114-114, Article 114

2020

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CED-4 forms a 2 : 2 heterotetrameric complex with CED-9 until specifically displaced by EGL-1 or CED-13

Cell death and differentiation, 2006-03, Vol.13 (3), p.426-434

2006

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Functional genomics approaches in parasitic helminths

Parasite immunology, 2012-02, Vol.34 (2-3), p.163-182

2012

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Characterisation of a novel A1-specific monoclonal antibody

Cell death & disease, 2014-12, Vol.5 (12), p.e1553-e1553

2014

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Relaxin and Prostaglandin E2 Regulate Interleukin 11 during Human Endometrial Stromal Cell Decidualization

The journal of clinical endocrinology and metabolism, 2005-06, Vol.90 (6), p.3458-3465

2005

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A transgenic mouse model to inducibly target prosurvival Bcl2 proteins with selective BH3 peptides in vivo

Cell death & disease, 2015-03, Vol.6 (3), p.e1679-e1679

2015

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MIC-1, a Novel Macrophage Inhibitory Cytokine, is a Divergent Member of the TGF-β superfamily

Proceedings of the National Academy of Sciences - PNAS, 1997-10, Vol.94 (21), p.11514-11519

1997

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Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1

Oncogene, 2002-06, Vol.21 (27), p.4212-4219

2002

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Relaxin and Prostaglandin E 2 Regulate Interleukin 11 during Human Endometrial Stromal Cell Decidualization

The journal of clinical endocrinology and metabolism, 2005-06, Vol.90 (6), p.3458-3465

2005

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Epitope Mapping of the Transforming Growth Factor-β Superfamily Protein, Macrophage Inhibitory Cytokine-1 (MIC-1): Identification of at Least Five Distinct Epitope Specificities

Biochemistry (Easton), 2001-01, Vol.40 (1), p.65-73

2001

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EGL-1 BH3 mutants reveal the importance of protein levels and target affinity for cell-killing potency

Cell death and differentiation, 2008-10, Vol.15 (10), p.1609-1618

2008

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Expression of growth differentiation factor-15/ macrophage inhibitory cytokine-1 (GDF-15/MIC-1) in the perinatal, adult, and injured rat brain

Journal of comparative neurology (1911), 2001-10, Vol.439 (1), p.32-45

2001

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Crystal structure of ABT-737 complexed with Bcl-x : implications for selectivity of antagonists of the Bcl-2 family

Cell death and differentiation, 2007-09, Vol.14 (9), p.1711-1713

2007

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BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival

Cell death & disease, 2019-04, Vol.10 (5), p.342-342, Article 342

2019

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The propeptide of macrophage inhibitory cytokine (MIC-1), a TGF-β superfamily member, acts as a quality control determinant for correctly folded MIC-1

The EMBO journal, 2000-05, Vol.19 (10), p.2212-2220

2000

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Affinity Maturation of Leukemia Inhibitory Factor and Conversion to Potent Antagonists of Signaling

The Journal of biological chemistry, 2004-01, Vol.279 (3), p.2125-2134

2004

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Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53

Genes & development, 2014-01, Vol.28 (1), p.58-70

2014

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The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia

MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activation

Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family

Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands

Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays

Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax

The transforming growth factor-β superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women

Antibody-Based Approach to High-Volume Genotyping for MIC-1 Polymorphism

BCL-XL is an actionable target for treatment of malignant pleural mesothelioma

CED-4 forms a 2 : 2 heterotetrameric complex with CED-9 until specifically displaced by EGL-1 or CED-13

Functional genomics approaches in parasitic helminths

Characterisation of a novel A1-specific monoclonal antibody

Relaxin and Prostaglandin E2 Regulate Interleukin 11 during Human Endometrial Stromal Cell Decidualization

A transgenic mouse model to inducibly target prosurvival Bcl2 proteins with selective BH3 peptides in vivo

MIC-1, a Novel Macrophage Inhibitory Cytokine, is a Divergent Member of the TGF-β superfamily

Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1

Relaxin and Prostaglandin E 2 Regulate Interleukin 11 during Human Endometrial Stromal Cell Decidualization

Epitope Mapping of the Transforming Growth Factor-β Superfamily Protein, Macrophage Inhibitory Cytokine-1 (MIC-1): Identification of at Least Five Distinct Epitope Specificities

EGL-1 BH3 mutants reveal the importance of protein levels and target affinity for cell-killing potency

Expression of growth differentiation factor-15/ macrophage inhibitory cytokine-1 (GDF-15/MIC-1) in the perinatal, adult, and injured rat brain

Crystal structure of ABT-737 complexed with Bcl-x : implications for selectivity of antagonists of the Bcl-2 family

BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival

The propeptide of macrophage inhibitory cytokine (MIC-1), a TGF-β superfamily member, acts as a quality control determinant for correctly folded MIC-1

Affinity Maturation of Leukemia Inhibitory Factor and Conversion to Potent Antagonists of Signaling

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53

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