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Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)

Cell death & disease, 2015-01, Vol.6 (1), p.e1590-e1590

2015

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RESCUE-ESE identifies candidate exonic splicing enhancers in vertebrate exons

Nucleic acids research, 2004-07, Vol.32 (Web Server issue), p.W187-W190

2004

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Predictive Identification of Exonic Splicing Enhancers in Human Genes

Science (American Association for the Advancement of Science), 2002-08, Vol.297 (5583), p.1007-1013

2002

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Human Genomic Sequences That Inhibit Splicing

Molecular and Cellular Biology, 2000-09, Vol.20 (18), p.6816-6825

2000

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ICEBERG: A Novel Inhibitor of Interleukin-1β Generation

Cell, 2000-09, Vol.103 (1), p.99-111

2000

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Characterizing photovoltaic backsheet adhesion degradation using the wedge and single cantilever beam tests, Part II: Accelerated tests

Solar energy materials and solar cells, 2020-07, Vol.211 (C), p.110524, Article 110524

2020

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Primary Splenic Angiosarcoma: Clinical and Imaging Manifestations of This Rare Aggressive Neoplasm

Current problems in diagnostic radiology, 2016-07, Vol.45 (4), p.284-287

2016

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69 ABT-199, a Selective Small Molecule Inhibitor of Bcl-2, Exhibits Efficacy in Bcl-2 Dependent Malignancies While Sparing Platelets

European journal of cancer (1990), 2012-11, Vol.48, p.23-23

2012

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High-throughput mapping of protein occupancy identifies functional elements without the restriction of a candidate factor approach

Nucleic acids research, 2011-03, Vol.39 (6), p.e33-e33

2011

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Antibody variable region binding by Staphylococcal protein A: Thermodynamic analysis and location of the Fv binding site on E-domain

Protein science, 1999-07, Vol.8 (7), p.1423-1431

1999

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Solution structure of the heparin-binding domain of vascular endothelial growth factor

Structure (London), 1998-05, Vol.6 (5), p.637-648

1998

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The PYRIN domain: A member of the death domain‐fold superfamily

Protein science, 2001-09, Vol.10 (9), p.1911-1918

2001

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Minimization of a Polypeptide Hormone

Science (American Association for the Advancement of Science), 1995-12, Vol.270 (5242), p.1657-1660

1995

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Identification of a Novel Death Domain-Containing Adaptor Molecule for Ectodysplasin-A Receptor that Is Mutated in crinkled Mice

Current biology, 2002-03, Vol.12 (5), p.409-413

2002

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Novel Peptides Selected to Bind Vascular Endothelial Growth Factor Target the Receptor-Binding Site

Biochemistry (Easton), 1998-12, Vol.37 (51), p.17754-17764

1998

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Monomeric variants of IL‐8: Effects of side chain substitutions and solution conditions upon dimer formation

Protein science, 1997-03, Vol.6 (3), p.598-608

1997

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Convergent Recognition of the IgE Binding Site on the High-Affinity IgE Receptor

Structure (London), 2004-07, Vol.12 (7), p.1289-1301

2004

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Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly(2)-Pro(1)-cleaving specificity

FEBS letters, 2006-03, Vol.580 (6), p.1581-1586

2006

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Selective Inhibition of Fibroblast Activation Protein Protease Based on Dipeptide Substrate Specificity

The Journal of biological chemistry, 2006-03, Vol.281 (11), p.7437-7444

2006

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393 Phase I pharmacokinetics and pharmacodynamics of GDC-0152, a novel IAP protein antagonist, administered to patients with locally advanced or metastatic malignancies

European journal of cancer supplements, 2010, Vol.8 (7), p.125-125

2010

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Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase

Nature structural biology, 1998-01, Vol.5 (1), p.47-54

1998

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82 Pharmacokinetic–pharmacodynamic modeling of the effect of GDC-0152, a selective antagonist of the inhibitor of apoptosis (IAP) proteins, on monocyte chemotactic protein-1 (MCP-1) indicates species differences in MCP-1 response

European journal of cancer supplements, 2010, Vol.8 (7), p.34-34

2010

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Growth Hormone Secretagogues: Characterization, Efficacy, and Minimal Bioactive Conformation

Proceedings of the National Academy of Sciences - PNAS, 1995-11, Vol.92 (24), p.11165-11169

1995

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Crystal Structure of the Complex between VEGF and a Receptor-Blocking Peptide

Biochemistry (Easton), 1998-12, Vol.37 (51), p.17765-17772

1998

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Single nucleotide polymorphism-based validation of exonic splicing enhancers

PLoS biology, 2004-09, Vol.2 (9), p.E268-E268

2004

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Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)

RESCUE-ESE identifies candidate exonic splicing enhancers in vertebrate exons

Predictive Identification of Exonic Splicing Enhancers in Human Genes

Human Genomic Sequences That Inhibit Splicing

ICEBERG: A Novel Inhibitor of Interleukin-1β Generation

Characterizing photovoltaic backsheet adhesion degradation using the wedge and single cantilever beam tests, Part II: Accelerated tests

Primary Splenic Angiosarcoma: Clinical and Imaging Manifestations of This Rare Aggressive Neoplasm

69 ABT-199, a Selective Small Molecule Inhibitor of Bcl-2, Exhibits Efficacy in Bcl-2 Dependent Malignancies While Sparing Platelets

High-throughput mapping of protein occupancy identifies functional elements without the restriction of a candidate factor approach

Antibody variable region binding by Staphylococcal protein A: Thermodynamic analysis and location of the Fv binding site on E-domain

Solution structure of the heparin-binding domain of vascular endothelial growth factor

The PYRIN domain: A member of the death domain‐fold superfamily

Minimization of a Polypeptide Hormone

Identification of a Novel Death Domain-Containing Adaptor Molecule for Ectodysplasin-A Receptor that Is Mutated in crinkled Mice

Novel Peptides Selected to Bind Vascular Endothelial Growth Factor Target the Receptor-Binding Site

Monomeric variants of IL‐8: Effects of side chain substitutions and solution conditions upon dimer formation

Convergent Recognition of the IgE Binding Site on the High-Affinity IgE Receptor

Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly(2)-Pro(1)-cleaving specificity

Selective Inhibition of Fibroblast Activation Protein Protease Based on Dipeptide Substrate Specificity

393 Phase I pharmacokinetics and pharmacodynamics of GDC-0152, a novel IAP protein antagonist, administered to patients with locally advanced or metastatic malignancies

Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase

82 Pharmacokinetic–pharmacodynamic modeling of the effect of GDC-0152, a selective antagonist of the inhibitor of apoptosis (IAP) proteins, on monocyte chemotactic protein-1 (MCP-1) indicates species differences in MCP-1 response

Growth Hormone Secretagogues: Characterization, Efficacy, and Minimal Bioactive Conformation

Crystal Structure of the Complex between VEGF and a Receptor-Blocking Peptide

Single nucleotide polymorphism-based validation of exonic splicing enhancers

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