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Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

Molecular cell, 2016-03, Vol.61 (6), p.834-849

2016

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Structure of HDAC3 bound to co-repressor and inositol tetraphosphate

Nature (London), 2012-01, Vol.481 (7381), p.335-340

2012

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Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

Molecular cell, 2013-07, Vol.51 (1), p.57-67

2013

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Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

Nature communications, 2018-01, Vol.9 (1), p.53-13, Article 53

2018

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Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex

Cell reports (Cambridge), 2020-02, Vol.30 (8), p.2699-2711.e8

2020

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Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

Nature communications, 2021-02, Vol.12 (1), p.819-17, Article 819

2021

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The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure

Nature communications, 2020-06, Vol.11 (1), p.3252-3252, Article 3252

2020

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EM Measurements Define the Dimensions of the "30-nm" Chromatin Fiber: Evidence for a Compact, Interdigitated Structure

Proceedings of the National Academy of Sciences - PNAS, 2006-04, Vol.103 (17), p.6506-6511

2006

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The structure of the core NuRD repression complex provides insights into its interaction with chromatin

eLife, 2016-04, Vol.5, p.e13941-e13941

2016

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Diverse nucleosome Site-Selectivity among histone deacetylase complexes

eLife, 2020-06, Vol.9

2020

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An evolving understanding of nuclear receptor coregulator proteins

Journal of molecular endocrinology, 2013-12, Vol.51 (3), p.T23-T36

2013

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How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structures

EMBO reports, 2005-01, Vol.6 (1), p.39-45

2005

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Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

Nature structural & molecular biology, 2011-02, Vol.18 (2), p.177-184

2011

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Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting

Nucleic acids research, 2015-02, Vol.43 (4), p.2033-2044

2015

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Hyperthyroxinemia and Hypercortisolemia due to Familial Dysalbuminemia

Thyroid (New York, N.Y.), 2020-11, Vol.30 (11), p.1681-1684

2020

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Negative regulation by nuclear receptors: a plethora of mechanisms

Trends in endocrinology and metabolism, 2011-03, Vol.22 (3), p.87-93

2011

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The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor

Genes & development, 2011-06, Vol.25 (12), p.1262-1274

2011

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FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (50), p.20107-20112

2011

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Structure of the TRFH Dimerization Domain of the Human Telomeric Proteins TRF1 and TRF2

Molecular cell, 2001-08, Vol.8 (2), p.351-361

2001

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The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain

PloS one, 2014-03, Vol.9 (3), p.e90889

2014

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Transient expression in HEK 293 cells: an alternative to E. coli for the production of secreted and intracellular mammalian proteins

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1258, p.209

2015

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Targeting Class I Histone Deacetylases in a “Complex” Environment

Trends in pharmacological sciences (Regular ed.), 2017-04, Vol.38 (4), p.363-377

2017

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Telomere architecture

EMBO reports, 2002-12, Vol.3 (12), p.1139-1145

2002

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Genetic disorders of nuclear receptors

The Journal of clinical investigation, 2017-04, Vol.127 (4), p.1181-1192

2017

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Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

Cell, 2018-10, Vol.175 (2), p.514-529.e20

2018

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Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

Structure of HDAC3 bound to co-repressor and inositol tetraphosphate

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure

EM Measurements Define the Dimensions of the "30-nm" Chromatin Fiber: Evidence for a Compact, Interdigitated Structure

The structure of the core NuRD repression complex provides insights into its interaction with chromatin

Diverse nucleosome Site-Selectivity among histone deacetylase complexes

An evolving understanding of nuclear receptor coregulator proteins

How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structures

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting

Hyperthyroxinemia and Hypercortisolemia due to Familial Dysalbuminemia

Negative regulation by nuclear receptors: a plethora of mechanisms

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors

Structure of the TRFH Dimerization Domain of the Human Telomeric Proteins TRF1 and TRF2

The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain

Transient expression in HEK 293 cells: an alternative to E. coli for the production of secreted and intracellular mammalian proteins

Targeting Class I Histone Deacetylases in a “Complex” Environment

Telomere architecture

Genetic disorders of nuclear receptors

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

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