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Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist

The Journal of pharmacology and experimental therapeutics, 2005-04, Vol.313 (1), p.176

2005

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4-(2-[2-(2(R)-Methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and Related 2-Aminoethylbenzofuran H3 Receptor Antagonists Potently Enhance Cognition and Attention

Journal of medicinal chemistry, 2005-01, Vol.48 (1), p.38-55

2005

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Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor

Journal of medicinal chemistry, 2009-05, Vol.52 (10), p.3377-3384

2009

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Advances in the Discovery of Novel Positive Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor

Recent patents on CNS drug discovery, 2007-06, Vol.2 (2)

2007

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Two novel and selective nonimidazole H3 receptor antagonists A-304121 and A-317920: II. In vivo behavioral and neurophysiological characterization

The Journal of pharmacology and experimental therapeutics, 2003-06, Vol.305 (3), p.897

2003

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Medicinal chemistry and biological properties of non-imidazole histamine H3 antagonists

Mini reviews in medicinal chemistry, 2004-11, Vol.4 (9), p.979-992

2004

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Effects of histamine H3 receptor ligands GT-2331 and ciproxifan in a repeated acquisition avoidance response in the spontaneously hypertensive rat pup

Behavioural brain research, 2002-04, Vol.131 (1-2), p.151-161

2002

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Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects

The Journal of pharmacology and experimental therapeutics, 2003-06, Vol.305 (3), p.887

2003

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Structure–activity relationships of arylbenzofuran H3 receptor antagonists

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (10), p.2559-2563

2005

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Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist

Biochemical pharmacology, 2004-09, Vol.68 (5), p.933-945

2004

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Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity

Biochemical pharmacology, 2007-04, Vol.73 (8), p.1243-1255

2007

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Synthesis and SAR of aminoalkoxy-biaryl-4-carboxamides: Novel and selective histamine H3 receptor antagonists

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (7), p.1325-1328

2003

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Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor

Journal of medicinal chemistry, 2008-02, Vol.51 (4), p.701-712

2008

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Differential in vivo effects of H3 receptor ligands in a new mouse dipsogenia model

Pharmacology, biochemistry and behavior, 2002-06, Vol.72 (3), p.741-750

2002

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Detection of multiple H3 receptor affinity states utilizing [3H]A‐349821, a novel, selective, non‐imidazole histamine H3 receptor inverse agonist radioligand

British journal of pharmacology, 2006-07, Vol.148 (5), p.657-670

2006

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Pharmacological Properties of ABT-239 [4-(2-{2-[(2 R )-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological Characterization and Broad Preclinical Efficacy in Cognition and Schizophrenia of a Potent and Selective Histamine H 3 Receptor Antagonist

The Journal of pharmacology and experimental therapeutics, 2005-04, Vol.313 (1), p.176-190

2005

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In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile

The Journal of pharmacology and experimental therapeutics, 2009-07, Vol.330 (1), p.257

2009

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Synthesis and Structure−Activity Relationships of 2-Pyridones: A Novel Series of Potent DNA Gyrase Inhibitors as Antibacterial Agents

Journal of medicinal chemistry, 1996-08, Vol.39 (16), p.3070-3088

1996

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Effect of novel motilide ABT-229 versus erythromycin and cisapride on gastric emptying in dogs

The Journal of pharmacology and experimental therapeutics, 2000-06, Vol.293 (3), p.1106

2000

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4-(2-[2-(2( R )-Methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and Related 2-Aminoethylbenzofuran H 3 Receptor Antagonists Potently Enhance Cognition and Attention

Journal of medicinal chemistry, 2005-01, Vol.48 (1), p.38-55

2005

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Allosteric modulators of the alpha7 nicotinic acetylcholine receptor

Journal of medicinal chemistry, 2008-02, Vol.51 (4), p.701-712

2008

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Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist

European journal of pharmacology, 2004-03, Vol.487 (1-3), p.183-197

2004

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Synthesis and SAR of 5-Amino- and 5-(Aminomethyl)benzofuran Histamine H 3 Receptor Antagonists with Improved Potency

Journal of medicinal chemistry, 2005-10, Vol.48 (20), p.6482-6490

2005

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Two Novel and Selective Nonimidazole H 3 Receptor Antagonists A-304121 and A-317920: II. In Vivo Behavioral and Neurophysiological Characterization

The Journal of pharmacology and experimental therapeutics, 2003-06, Vol.305 (3), p.897-908

2003

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Two Novel and Selective Nonimidazole Histamine H 3 Receptor Antagonists A-304121 and A-317920: I. In Vitro Pharmacological Effects

The Journal of pharmacology and experimental therapeutics, 2003-06, Vol.305 (3), p.887-896

2003

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Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist

4-(2-[2-(2(R)-Methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and Related 2-Aminoethylbenzofuran H3 Receptor Antagonists Potently Enhance Cognition and Attention

Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor

Advances in the Discovery of Novel Positive Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor

Two novel and selective nonimidazole H3 receptor antagonists A-304121 and A-317920: II. In vivo behavioral and neurophysiological characterization

Medicinal chemistry and biological properties of non-imidazole histamine H3 antagonists

Effects of histamine H3 receptor ligands GT-2331 and ciproxifan in a repeated acquisition avoidance response in the spontaneously hypertensive rat pup

Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects

Structure–activity relationships of arylbenzofuran H3 receptor antagonists

Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist

Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity

Synthesis and SAR of aminoalkoxy-biaryl-4-carboxamides: Novel and selective histamine H3 receptor antagonists

Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor

Differential in vivo effects of H3 receptor ligands in a new mouse dipsogenia model

Detection of multiple H3 receptor affinity states utilizing [3H]A‐349821, a novel, selective, non‐imidazole histamine H3 receptor inverse agonist radioligand

Pharmacological Properties of ABT-239 [4-(2-{2-[(2 R )-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological Characterization and Broad Preclinical Efficacy in Cognition and Schizophrenia of a Potent and Selective Histamine H 3 Receptor Antagonist

In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile

Synthesis and Structure−Activity Relationships of 2-Pyridones: A Novel Series of Potent DNA Gyrase Inhibitors as Antibacterial Agents

Effect of novel motilide ABT-229 versus erythromycin and cisapride on gastric emptying in dogs

4-(2-[2-(2( R )-Methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and Related 2-Aminoethylbenzofuran H 3 Receptor Antagonists Potently Enhance Cognition and Attention

Allosteric modulators of the alpha7 nicotinic acetylcholine receptor

Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist

Synthesis and SAR of 5-Amino- and 5-(Aminomethyl)benzofuran Histamine H 3 Receptor Antagonists with Improved Potency

Two Novel and Selective Nonimidazole H 3 Receptor Antagonists A-304121 and A-317920: II. In Vivo Behavioral and Neurophysiological Characterization

Two Novel and Selective Nonimidazole Histamine H 3 Receptor Antagonists A-304121 and A-317920: I. In Vitro Pharmacological Effects

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