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Presentation of a modified dispersion model (MDM) for hepatic drug extraction and a new methodology for the prediction of the rate-limiting step in hepatic metabolic clearance

Xenobiotica, 2009-01, Vol.39 (1), p.57-71

Fagerholm, U.

2009

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Comparison between active and passive drug transport in human intestinal epithelial (caco-2) cells in vitro and human jejunum in vivo

International journal of pharmaceutics, 1996-01, Vol.127 (1), p.103-107

1996

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The highly permeable blood–brain barrier: an evaluation of current opinions about brain uptake capacity

Drug discovery today, 2007-12, Vol.12 (23), p.1076-1082

Fagerholm, Urban

2007

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Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans

Gut, 2003-11, Vol.52 (11), p.1537-1542

2003

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Prediction of human pharmacokinetics - evaluation of methods for prediction of volume of distribution

Journal of pharmacy and pharmacology, 2007-09, Vol.59 (9), p.1181-1190

Fagerholm, Urban

2007

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Prediction of human pharmacokinetics-evaluation of methods for prediction of hepatic metabolic clearance

Journal of pharmacy and pharmacology, 2007-06, Vol.59 (6), p.803-828

Fagerholm, Urban

2007

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Prediction of human pharmacokinetics -gastrointestinal absorption

Journal of pharmacy and pharmacology, 2007-07, Vol.59 (7), p.905-916

Fagerholm, Urban

2007

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Prediction of human pharmacokinetics - renal metabolic and excretion clearance

Journal of pharmacy and pharmacology, 2007-11, Vol.59 (11), p.1463-1471

Fagerholm, Urban

2007

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Prediction of human pharmacokinetics-biliary and intestinal clearance and enterohepatic circulation

Journal of pharmacy and pharmacology, 2008-05, Vol.60 (5), p.535-542

Fagerholm, Urban

2008

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An integral link

British dental journal, 2011-04, Vol.210 (8), p.344-344

2011

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Pre-clinical pharmacokinetics of the cyclooxygenase-inhibiting nitric oxide donor (CINOD) AZD3582

Journal of pharmacy and pharmacology, 2005-05, Vol.57 (5), p.587-597

2005

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Prediction of human pharmacokinetics-gut-wall metabolism

Journal of pharmacy and pharmacology, 2007-10, Vol.59 (10), p.1335-1343

Fagerholm, Urban

2007

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Evaluation and suggested improvements of the Biopharmaceutics Classification System (BCS)

Journal of pharmacy and pharmacology, 2007-06, Vol.59 (6), p.751-757

Fagerholm, Urban

2007

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Prediction of human pharmacokinetics - improving microsome-based predictions of hepatic metabolic clearance

Journal of pharmacy and pharmacology, 2007-10, Vol.59 (10), p.1427-1431

Fagerholm, Urban

2007

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Comparison between permeability coefficients in rat and human jejunum

Pharmaceutical research, 1996-09, Vol.13 (9), p.1336-1342

1996

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Prediction of in vivo rat biliary drug clearance from an in vitro hepatocyte efflux model

Drug metabolism and disposition, 2014-03, Vol.42 (3), p.459-468

2014

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Characterization of jejunal absorption and apical efflux of ropivacaine, lidocaine and bupivacaine in the rat using in situ and in vitro absorption models

European journal of pharmaceutical sciences, 2004-03, Vol.21 (4), p.553-560

2004

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Jejunal permeability in humans in vivo and rats in situ : investigation of molecular size selectivity and solvent drag

Acta physiologica Scandinavica, 1999-03, Vol.165 (3), p.315-324

1999

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Clinical pharmacokinetics of the cyclooxygenase inhibiting nitric oxide donator (CINOD) AZD3582

Journal of pharmacy and pharmacology, 2005-12, Vol.57 (12), p.1539-1554

2005

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Regional Intestinal Permeability in Rats of Compounds with Different Physicochemical Properties and Transport Mechanisms

Journal of pharmacy and pharmacology, 1997-07, Vol.49 (7), p.687-690

1997

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Experimental estimation of the effective unstirred water layer thickness in the human jejunum, and its importance in oral drug absorption

European journal of pharmaceutical sciences, 1995-10, Vol.3 (5), p.247-253

1995

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The influence of net water absorption on the permeability of antipyrine and levodopa in the human jejunum

Pharmaceutical research, 1994-11, Vol.11 (11), p.1540-1544

1994

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A Residence-Time Distribution Analysis of the Hydrodynamics within the Intestine in Man during a Regional Single-pass Perfusion with Loc-I-Gut: In-vivo Permeability Estimation

Journal of pharmacy and pharmacology, 1997-07, Vol.49 (7), p.682-686

1997

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P44 Estimation of the unstirred water layer thickness in the human small intestine, and its importance in oral drug absorption

European journal of pharmaceutical sciences, 1994, Vol.2 (1), p.129-129

1994

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P45 The correlation between rat and human small intestinal premeability to drugs with different physico-chemical properties

European journal of pharmaceutical sciences, 1994, Vol.2 (1), p.130-130

1994

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Presentation of a modified dispersion model (MDM) for hepatic drug extraction and a new methodology for the prediction of the rate-limiting step in hepatic metabolic clearance

Comparison between active and passive drug transport in human intestinal epithelial (caco-2) cells in vitro and human jejunum in vivo

The highly permeable blood–brain barrier: an evaluation of current opinions about brain uptake capacity

Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans

Prediction of human pharmacokinetics - evaluation of methods for prediction of volume of distribution

Prediction of human pharmacokinetics-evaluation of methods for prediction of hepatic metabolic clearance

Prediction of human pharmacokinetics -gastrointestinal absorption

Prediction of human pharmacokinetics - renal metabolic and excretion clearance

Prediction of human pharmacokinetics-biliary and intestinal clearance and enterohepatic circulation

An integral link

Pre-clinical pharmacokinetics of the cyclooxygenase-inhibiting nitric oxide donor (CINOD) AZD3582

Prediction of human pharmacokinetics-gut-wall metabolism

Evaluation and suggested improvements of the Biopharmaceutics Classification System (BCS)

Prediction of human pharmacokinetics - improving microsome-based predictions of hepatic metabolic clearance

Comparison between permeability coefficients in rat and human jejunum

Prediction of in vivo rat biliary drug clearance from an in vitro hepatocyte efflux model

Characterization of jejunal absorption and apical efflux of ropivacaine, lidocaine and bupivacaine in the rat using in situ and in vitro absorption models

Jejunal permeability in humans in vivo and rats in situ : investigation of molecular size selectivity and solvent drag

Clinical pharmacokinetics of the cyclooxygenase inhibiting nitric oxide donator (CINOD) AZD3582

Regional Intestinal Permeability in Rats of Compounds with Different Physicochemical Properties and Transport Mechanisms

Experimental estimation of the effective unstirred water layer thickness in the human jejunum, and its importance in oral drug absorption

The influence of net water absorption on the permeability of antipyrine and levodopa in the human jejunum

A Residence-Time Distribution Analysis of the Hydrodynamics within the Intestine in Man during a Regional Single-pass Perfusion with Loc-I-Gut: In-vivo Permeability Estimation

P44 Estimation of the unstirred water layer thickness in the human small intestine, and its importance in oral drug absorption

P45 The correlation between rat and human small intestinal premeability to drugs with different physico-chemical properties

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