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Specific Mutations near the Amyloid Precursor Protein Cleavage Site Increase γ-Secretase Sensitivity and Modulate Amyloid-β Production

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3970

2023

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Specific mutations in presenilin 1 cause conformational changes in γ-secretase to modulate amyloid β trimming

Journal of biochemistry (Tokyo), 2019-01, Vol.165 (1), p.37-46

2019

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Specific Mutations in Aph1 Cause γ-Secretase Activation

International journal of molecular sciences, 2022-01, Vol.23 (1), p.507

2022

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Microcystis viridis NIES-102 Cyanobacteria Lectin (MVL) Interacts with SARS-CoV-2 Spike Protein Receptor Binding Domains (RBDs) via Protein–Protein Interaction

International journal of molecular sciences, 2024-06, Vol.25 (12), p.6696

2024

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Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle

Cell, 2005-08, Vol.122 (4), p.605-617

2005

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A Metalloproteinase Cocktail from the Venom of Protobothrops flavoviridis Cleaves Amyloid Beta Peptides at the α-Cleavage Site

Toxins, 2023-08, Vol.15 (8), p.500

2023

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Phosphatidylethanolamine plasmalogen enhances the inhibiting effect of phosphatidylethanolamine on γ-secretase activity

Journal of biochemistry (Tokyo), 2015-05, Vol.157 (5), p.301-309

2015

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Advanced Yeast Models of Familial Alzheimer Disease Expressing FAD-Linked Presenilin to Screen Mutations and γ-Secretase Modulators

Methods in molecular biology (Clifton, N.J.), 2019, Vol.2049, p.403

Futai, Eugene

2019

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Focused Proteomics Analysis of Habu Snake (Protobothrops flavoviridis) Venom Using Antivenom-Based Affinity Chromatography Reveals Novel Myonecrosis-Enhancing Activity of Thrombin-Like Serine Proteases

Frontiers in pharmacology, 2021-11, Vol.12, p.766406-766406

2021

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Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat

The EMBO journal, 2012-02, Vol.31 (4), p.1014-1027

2012

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Multibudded tubules formed by COPII on artificial liposomes

Scientific reports, 2011-06, Vol.1 (1), p.17-17, Article 17

2011

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Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation

Cells (Basel, Switzerland), 2020-02, Vol.9 (2), p.349

2020

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Dysbindin-1, a schizophrenia-related protein, functionally interacts with the DNA- dependent protein kinase complex in an isoform-dependent manner

PloS one, 2009-01, Vol.4 (1), p.e4199-e4199

2009

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Localization of mature neprilysin in lipid rafts

Journal of neuroscience research, 2012-04, Vol.90 (4), p.870-877

2012

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Production of Anti-Amyloid β Antibodies in Mice Fed Rice Expressing Amyloid β

Bioscience, biotechnology, and biochemistry, 2011, Vol.75 (2), p.396-400

2011

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Transgenic rice expressing amyloid β-peptide for oral immunization

International journal of biological sciences, 2011-01, Vol.7 (3), p.301-307

2011

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Expression of polyalanine stretches induces mitochondrial dysfunction

Journal of neuroscience research, 2008-05, Vol.86 (7), p.1529-1537

2008

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Inhibition by KMI-574 leads to dislocalization of BACE1 from lipid rafts

Journal of neuroscience research, 2009-02, Vol.87 (2), p.360-368

2009

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Microcystis viridis NIES-102 Cyanobacteria Lectin via Protein–Protein Interaction

International journal of molecular sciences, 2024-06, Vol.25 (12)

2024

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Functional properties of gamma-secretase in the yeast reconstitution system

Seikagaku. The Journal of Japanese Biochemical Society, 2016-04, Vol.88 (2), p.215

Futai, Eugene

2016

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Polyalanine tracts directly induce the release of cytochrome c, independently of the mitochondrial permeability transition pore, leading to apoptosis

Genes to cells : devoted to molecular & cellular mechanisms, 2009-06, Vol.14 (6), p.751-757

2009

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PTBP1 regulates the alternative splicing of dopamine receptor D2 (DRD2)

Neuroscience research, 2009, Vol.65, p.S90-S90

2009

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A Metalloproteinase Cocktail from the Venom of IProtobothrops flavoviridis/I Cleaves Amyloid Beta Peptides at the α-Cleavage Site

Toxins, 2023-08, Vol.15 (8)

2023

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C-terminal amino acids in the type I transmembrane domain of L-type lectin VIP36 affect γ-secretase susceptibility

Biochemical and biophysical research communications, 2024-02, Vol.696, p.149504-149504, Article 149504

2024

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Suppressor Mutations for Presenilin 1 Familial Alzheimer Disease Mutants Modulate γ-Secretase Activities

The Journal of biological chemistry, 2016-01, Vol.291 (1), p.435-446

2016

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Specific Mutations near the Amyloid Precursor Protein Cleavage Site Increase γ-Secretase Sensitivity and Modulate Amyloid-β Production

Specific mutations in presenilin 1 cause conformational changes in γ-secretase to modulate amyloid β trimming

Specific Mutations in Aph1 Cause γ-Secretase Activation

Microcystis viridis NIES-102 Cyanobacteria Lectin (MVL) Interacts with SARS-CoV-2 Spike Protein Receptor Binding Domains (RBDs) via Protein–Protein Interaction

Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle

A Metalloproteinase Cocktail from the Venom of Protobothrops flavoviridis Cleaves Amyloid Beta Peptides at the α-Cleavage Site

Phosphatidylethanolamine plasmalogen enhances the inhibiting effect of phosphatidylethanolamine on γ-secretase activity

Advanced Yeast Models of Familial Alzheimer Disease Expressing FAD-Linked Presenilin to Screen Mutations and γ-Secretase Modulators

Focused Proteomics Analysis of Habu Snake (Protobothrops flavoviridis) Venom Using Antivenom-Based Affinity Chromatography Reveals Novel Myonecrosis-Enhancing Activity of Thrombin-Like Serine Proteases

Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat

Multibudded tubules formed by COPII on artificial liposomes

Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation

Dysbindin-1, a schizophrenia-related protein, functionally interacts with the DNA- dependent protein kinase complex in an isoform-dependent manner

Localization of mature neprilysin in lipid rafts

Production of Anti-Amyloid β Antibodies in Mice Fed Rice Expressing Amyloid β

Transgenic rice expressing amyloid β-peptide for oral immunization

Expression of polyalanine stretches induces mitochondrial dysfunction

Inhibition by KMI-574 leads to dislocalization of BACE1 from lipid rafts

Microcystis viridis NIES-102 Cyanobacteria Lectin via Protein–Protein Interaction

Functional properties of gamma-secretase in the yeast reconstitution system

Polyalanine tracts directly induce the release of cytochrome c, independently of the mitochondrial permeability transition pore, leading to apoptosis

PTBP1 regulates the alternative splicing of dopamine receptor D2 (DRD2)

A Metalloproteinase Cocktail from the Venom of IProtobothrops flavoviridis/I Cleaves Amyloid Beta Peptides at the α-Cleavage Site

C-terminal amino acids in the type I transmembrane domain of L-type lectin VIP36 affect γ-secretase susceptibility

Suppressor Mutations for Presenilin 1 Familial Alzheimer Disease Mutants Modulate γ-Secretase Activities

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