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Structure-Assisted Design of Mechanism-Based Irreversible Inhibitors of Human Rhinovirus 3C Protease with Potent Antiviral Activity against Multiple Rhinovirus Serotypes

Proceedings of the National Academy of Sciences - PNAS, 1999-09, Vol.96 (20), p.11000-11007

1999

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In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human Rhinovirus 3C Protease

Antimicrobial Agents and Chemotherapy, 1999-10, Vol.43 (10), p.2444-2450

1999

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Toxoplasma gondii: fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblasts

Science (American Association for the Advancement of Science), 1990-08, Vol.249 (4969), p.641-646

1990

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Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C Protease

Journal of medicinal chemistry, 1996-12, Vol.39 (26), p.5072-5082

1996

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2806-2818

1998

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2819-2834

1998

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 3. Structure−Activity Studies of Ketomethylene-Containing Peptidomimetics

Journal of medicinal chemistry, 1999-04, Vol.42 (7), p.1203-1212

1999

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Prognostic significance of morphologic parameters in renal cell carcinoma

The American journal of surgical pathology, 1982-10, Vol.6 (7), p.655-664

1982

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Metabolomics Reveals Dynamic Metabolic Changes Associated with Age in Early Childhood

PloS one, 2016-02, Vol.11 (2), p.e0149823-e0149823

2016

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 4. Incorporation of P1 Lactam Moieties as l-Glutamine Replacements

Journal of medicinal chemistry, 1999-04, Vol.42 (7), p.1213-1224

1999

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Recruiting population controls for case-control studies in sub-Saharan Africa: The Ghana Breast Health Study

PloS one, 2019-04, Vol.14 (4), p.e0215347-e0215347

2019

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Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors

Bioorganic & medicinal chemistry letters, 2000-01, Vol.10 (1), p.45-48

2000

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Serum inhibin B concentration as a predictor of age at first menstruation in girls with idiopathic central precocious puberty

PloS one, 2018-12, Vol.13 (12), p.e0205810-e0205810

2018

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Genetic Polymorphisms in Vitamin D Metabolism and Signaling Genes and Risk of Breast Cancer: A Nested Case-Control Study

PloS one, 2015-10, Vol.10 (10), p.e0140478-e0140478

2015

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Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients

PloS one, 2017-08, Vol.12 (8), p.e0183579-e0183579

2017

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Obesity and Cardio-Metabolic Risk Factors in an Urban and Rural Population in the Ashanti Region-Ghana: A Comparative Cross-Sectional Study

PloS one, 2015-06, Vol.10 (6), p.e0129494-e0129494

2015

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Merging Children's Oncology Group Data with an External Administrative Database Using Indirect Patient Identifiers: A Report from the Children's Oncology Group

PloS one, 2015-11, Vol.10 (11), p.e0143480

2015

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Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids

Bioorganic & medicinal chemistry letters, 1999-08, Vol.9 (15), p.2189-2194

1999

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Associations of Serum Levels of Sex Hormones in Follicular and Luteal Phases of the Menstrual Cycle with Breast Tissue Characteristics in Young Women

PloS one, 2016-10, Vol.11 (10), p.e0163865

2016

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Association between Self-Reported Smoking and Hemoglobin A1c in a Korean Population without Diabetes: The 2011-2012 Korean National Health and Nutrition Examination Survey

PloS one, 2015-05, Vol.10 (5), p.e0126746-e0126746

2015

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Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease: Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P1 Glutamine Isosteric Replacements

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2786-2805

1998

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Toxoplasma gondii: mechanism of resistance to complement-mediated killing

The Journal of immunology (1950), 1989-02, Vol.142 (3), p.940-947

1989

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HeLa cell RNA polymerase III transcription factors. Functional characterization of a fraction identified by its activity in a second template rescue assay

The Journal of biological chemistry, 1984-02, Vol.259 (3), p.1934-1943

1984

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Delivering clinical laboratory services to intensive care units

Clinical chemistry (Baltimore, Md.), 1996-03, Vol.42 (3), p.387-391

1996

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Constraining the composition and quantity of organic matter used by abundant marine Thaumarchaeota

Environmental microbiology, 2023-03, Vol.25 (3), p.689-704

2023

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Structure-Assisted Design of Mechanism-Based Irreversible Inhibitors of Human Rhinovirus 3C Protease with Potent Antiviral Activity against Multiple Rhinovirus Serotypes

In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human Rhinovirus 3C Protease

Toxoplasma gondii: fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblasts

Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C Protease

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 3. Structure−Activity Studies of Ketomethylene-Containing Peptidomimetics

Prognostic significance of morphologic parameters in renal cell carcinoma

Metabolomics Reveals Dynamic Metabolic Changes Associated with Age in Early Childhood

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 4. Incorporation of P1 Lactam Moieties as l-Glutamine Replacements

Recruiting population controls for case-control studies in sub-Saharan Africa: The Ghana Breast Health Study

Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors

Serum inhibin B concentration as a predictor of age at first menstruation in girls with idiopathic central precocious puberty

Genetic Polymorphisms in Vitamin D Metabolism and Signaling Genes and Risk of Breast Cancer: A Nested Case-Control Study

Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients

Obesity and Cardio-Metabolic Risk Factors in an Urban and Rural Population in the Ashanti Region-Ghana: A Comparative Cross-Sectional Study

Merging Children's Oncology Group Data with an External Administrative Database Using Indirect Patient Identifiers: A Report from the Children's Oncology Group

Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids

Associations of Serum Levels of Sex Hormones in Follicular and Luteal Phases of the Menstrual Cycle with Breast Tissue Characteristics in Young Women

Association between Self-Reported Smoking and Hemoglobin A1c in a Korean Population without Diabetes: The 2011-2012 Korean National Health and Nutrition Examination Survey

Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease: Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P1 Glutamine Isosteric Replacements

Toxoplasma gondii: mechanism of resistance to complement-mediated killing

HeLa cell RNA polymerase III transcription factors. Functional characterization of a fraction identified by its activity in a second template rescue assay

Delivering clinical laboratory services to intensive care units

Constraining the composition and quantity of organic matter used by abundant marine Thaumarchaeota

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