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Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV‑2 nsp3

Biochemistry (Easton), 2020-07, Vol.59 (28), p.2608-2615

2020

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Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug

Journal of antimicrobial chemotherapy, 2012-08, Vol.67 (8), p.1884-1894

2012

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DNA PRIMASES

Annual review of biochemistry, 2001-01, Vol.70 (1), p.39-80

2001

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Hepatitis C Virus Subgenomic Replicon Requires an Active NS3 RNA Helicase

Journal of Virology, 2006-01, Vol.80 (1), p.404-411

2006

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Aurintricarboxylic Acid Modulates the Affinity of Hepatitis C Virus NS3 Helicase for Both Nucleic Acid and ATP

Biochemistry (Easton), 2013-09, Vol.52 (36), p.6151-6159

2013

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PSI-7851, a Pronucleotide of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication

Antimicrobial Agents and Chemotherapy, 2010-08, Vol.54 (8), p.3187-3196

2010

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Cuff and Bladder: Overlooked Components of BP Measurement Devices in the Modern Era?

American journal of hypertension, 2012-02, Vol.25 (2), p.136-138

2012

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A transplant recipient's pandemic perspective

Transplant infectious disease, 2021-10, Vol.23 (5), p.e13738-n/a

Frick, David N.

2021

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Monitoring helicase activity with molecular beacons

BioTechniques, 2008-10, Vol.45 (4), p.433-442

2008

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Fluorescent probe displacement assays reveal unique nucleic acid binding properties of human nudix enzymes

Analytical biochemistry, 2020-04, Vol.595, p.113622-113622, Article 113622

2020

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The Patient Reported Outcomes, Burdens and Experiences (PROBE) Project: development and evaluation of a questionnaire assessing patient reported outcomes in people with haemophilia

Pilot and feasibility studies, 2018-02, Vol.4 (1), p.58-58, Article 58

2018

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Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays

Nucleic acids research, 2012-09, Vol.40 (17), p.8607-8621

2012

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The Nonstructural Protein 3 Protease/Helicase Requires an Intact Protease Domain to Unwind Duplex RNA Efficiently

The Journal of biological chemistry, 2004-01, Vol.279 (2), p.1269-1280

2004

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Understanding helicases as a means of virus control

Current pharmaceutical design, 2006-04, Vol.12 (11), p.1315-1338

2006

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The interdomain interface in bifunctional enzyme protein 3/4A (NS3/4A) regulates protease and helicase activities

Protein science, 2013-12, Vol.22 (12), p.1786-1798

2013

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The MutT Proteins or “Nudix” Hydrolases, a Family of Versatile, Widely Distributed, “Housecleaning” Enzymes

The Journal of biological chemistry, 1996-10, Vol.271 (41), p.25059-25062

1996

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Intermediary metabolism of Arctic char Salvelinus alpinus during short-term salinity exposure

Journal of experimental biology, 2007-06, Vol.210 (Pt 11), p.1971-1985

2007

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DNA damage alters DNA polymerase to a form that exhibits increased discrimination against modified template bases and mismatched primers

Nucleic acids research, 2009-02, Vol.37 (2), p.647-657

2009

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Analysis of the Enzymatic Activity of an NS3 Helicase Genotype 3a Variant Sequence Obtained from a Relapse Patient

PloS one, 2015-12, Vol.10 (12), p.e0144638-e0144638

2015

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Dimerization-driven interaction of hepatitis C virus core protein with NS3 helicase

Journal of general virology, 2011, Vol.92 (Pt 1), p.101-111

2011

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Two Novel Conserved Motifs in the Hepatitis C Virus NS3 Protein Critical for Helicase Action

The Journal of biological chemistry, 2003-11, Vol.278 (45), p.44514-44524

2003

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Mechanism and Specificity of a Symmetrical Benzimidazolephenylcarboxamide Helicase Inhibitor

Biochemistry (Easton), 2010-03, Vol.49 (9), p.1822-1832

2010

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Nitrogen metabolism and excretion in the mangrove killifish Rivulus marmoratus I. The influence of environmental salinity and external ammonia

Journal of experimental biology, 2002-01, Vol.205 (Pt 1), p.79-89

2002

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Fuel Specificity of the Hepatitis C Virus NS3 Helicase

Journal of molecular biology, 2009-05, Vol.388 (4), p.851-864

2009

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Computer-aided identification, synthesis and evaluation of substituted thienopyrimidines as novel inhibitors of HCV replication

European journal of medicinal chemistry, 2016-11, Vol.123, p.31-47

2016

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Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV‑2 nsp3

Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug

DNA PRIMASES

Hepatitis C Virus Subgenomic Replicon Requires an Active NS3 RNA Helicase

Aurintricarboxylic Acid Modulates the Affinity of Hepatitis C Virus NS3 Helicase for Both Nucleic Acid and ATP

PSI-7851, a Pronucleotide of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication

Cuff and Bladder: Overlooked Components of BP Measurement Devices in the Modern Era?

A transplant recipient's pandemic perspective

Monitoring helicase activity with molecular beacons

Fluorescent probe displacement assays reveal unique nucleic acid binding properties of human nudix enzymes

The Patient Reported Outcomes, Burdens and Experiences (PROBE) Project: development and evaluation of a questionnaire assessing patient reported outcomes in people with haemophilia

Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays

The Nonstructural Protein 3 Protease/Helicase Requires an Intact Protease Domain to Unwind Duplex RNA Efficiently

Understanding helicases as a means of virus control

The interdomain interface in bifunctional enzyme protein 3/4A (NS3/4A) regulates protease and helicase activities

The MutT Proteins or “Nudix” Hydrolases, a Family of Versatile, Widely Distributed, “Housecleaning” Enzymes

Intermediary metabolism of Arctic char Salvelinus alpinus during short-term salinity exposure

DNA damage alters DNA polymerase to a form that exhibits increased discrimination against modified template bases and mismatched primers

Analysis of the Enzymatic Activity of an NS3 Helicase Genotype 3a Variant Sequence Obtained from a Relapse Patient

Dimerization-driven interaction of hepatitis C virus core protein with NS3 helicase

Two Novel Conserved Motifs in the Hepatitis C Virus NS3 Protein Critical for Helicase Action

Mechanism and Specificity of a Symmetrical Benzimidazolephenylcarboxamide Helicase Inhibitor

Nitrogen metabolism and excretion in the mangrove killifish Rivulus marmoratus I. The influence of environmental salinity and external ammonia

Fuel Specificity of the Hepatitis C Virus NS3 Helicase

Computer-aided identification, synthesis and evaluation of substituted thienopyrimidines as novel inhibitors of HCV replication

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