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The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

Nucleic acids research, 1997-11, Vol.25 (22), p.4429

1997

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PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules

Nature (London), 1993-10, Vol.365 (6446), p.566-568

1993

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Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression

The Journal of biological chemistry, 1993-07, Vol.268 (19), p.14514-14522

1993

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Fully modified 2' MOE oligonucleotides redirect polyadenylation

Nucleic acids research, 2001-03, Vol.29 (6), p.1293

2001

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Thermodynamic criteria for high hit rate antisense oligonucleotide design

Nucleic acids research, 2003-09, Vol.31 (17), p.4989

2003

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Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Journal of medicinal chemistry, 1993-04, Vol.36 (7), p.831-841

1993

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Improved Free-Energy Parameters for Predictions of RNA Duplex Stability

Proceedings of the National Academy of Sciences - PNAS, 1986-12, Vol.83 (24), p.9373-9377

1986

Volltextzugriff (PDF)

Expression of the insulin-like growth factors and their receptors in adenocarcinoma of the colon

Gut, 1999-05, Vol.44 (5), p.704-708

1999

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Predicting oligonucleotide affinity to nucleic acid targets

RNA (Cambridge), 1999-11, Vol.5 (11), p.1458-1469, Article S1355838299991148

1999

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Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms

The Journal of biological chemistry, 1991-09, Vol.266 (27), p.18162-18171

1991

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Relative Thermodynamic Stability of DNA, RNA, and DNA:RNA Hybrid Duplexes: Relationship with Base Composition and Structure

Biochemistry (Easton), 1995-08, Vol.34 (34), p.10807-10815

1995

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Implication of RNA structure on antisense oligonucleotide hybridization kinetics

Biochemistry (Easton), 1992-12, Vol.31 (48), p.12055-12061

1992

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Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides

The Journal of biological chemistry, 1992-10, Vol.267 (28), p.19954-19962

1992

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Identification of sequence motifs in oligonucleotides whose presence is correlated with antisense activity

Nucleic acids research, 2000-08, Vol.28 (15), p.2862

2000

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Effects of RNA secondary structure on cellular antisense activity

Nucleic acids research, 2000-03, Vol.28 (6), p.1340

2000

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Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

Biochemistry (Easton), 1993-08, Vol.32 (30), p.7832-7838

1993

Volltextzugriff (PDF)

Amides as a New Type of Backbone Modification in Oligonucleotides

Angewandte Chemie (International ed.), 1994-02, Vol.33 (2), p.226-229

1994

Volltextzugriff (PDF)

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

Cell metabolism, 2006-02, Vol.3 (2), p.87-98

2006

Volltextzugriff (PDF)

Sequence-Specific Antitumor Activity of a Phosphorothioate Oligodeoxyribonucleotide Targeted to Human C-Raf Kinase Supports an Antisense Mechanism of Action in vivo

Proceedings of the National Academy of Sciences - PNAS, 1996-12, Vol.93 (26), p.15481-15484

1996

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Deconvolution of Combinatorial Libraries for Drug Discovery: A Model System

Journal of medicinal chemistry, 1995-01, Vol.38 (2), p.344-352

1995

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Kinetics of G-Quartet-Mediated Tetramer Formation

Biochemistry (Easton), 1996-06, Vol.35 (24), p.8002-8008

1996

Volltextzugriff (PDF)

Pseudo-Half-Knot Formation with RNA

Science (American Association for the Advancement of Science), 1992-08, Vol.257 (5072), p.958-961

1992

Volltextzugriff (PDF)

Patterns of variant polyadenylation signal usage in human genes

Genome research, 2000-07, Vol.10 (7), p.1001

2000

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Deconvolution of Combinatorial Libraries for Drug Discovery: Experimental Comparison of Pooling Strategies

Journal of medicinal chemistry, 1996-07, Vol.39 (14), p.2720-2726

1996

Volltextzugriff (PDF)

Elevated levels of Rad51 recombination protein in tumor cells

Cancer research (Chicago, Ill.), 2002, Vol.62 (1), p.219-225

2002

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The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules

Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression

Fully modified 2' MOE oligonucleotides redirect polyadenylation

Thermodynamic criteria for high hit rate antisense oligonucleotide design

Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Improved Free-Energy Parameters for Predictions of RNA Duplex Stability

Expression of the insulin-like growth factors and their receptors in adenocarcinoma of the colon

Predicting oligonucleotide affinity to nucleic acid targets

Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms

Relative Thermodynamic Stability of DNA, RNA, and DNA:RNA Hybrid Duplexes: Relationship with Base Composition and Structure

Implication of RNA structure on antisense oligonucleotide hybridization kinetics

Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides

Identification of sequence motifs in oligonucleotides whose presence is correlated with antisense activity

Effects of RNA secondary structure on cellular antisense activity

Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

Amides as a New Type of Backbone Modification in Oligonucleotides

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

Sequence-Specific Antitumor Activity of a Phosphorothioate Oligodeoxyribonucleotide Targeted to Human C-Raf Kinase Supports an Antisense Mechanism of Action in vivo

Deconvolution of Combinatorial Libraries for Drug Discovery: A Model System

Kinetics of G-Quartet-Mediated Tetramer Formation

Pseudo-Half-Knot Formation with RNA

Patterns of variant polyadenylation signal usage in human genes

Deconvolution of Combinatorial Libraries for Drug Discovery: Experimental Comparison of Pooling Strategies

Elevated levels of Rad51 recombination protein in tumor cells

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