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Overcoming IGF1R/IR Resistance through Inhibition of MEK Signaling in Colorectal Cancer Models

Clinical cancer research, 2013-11, Vol.19 (22), p.6219-6229

2013

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Development of an Integrated Genomic Classifier for a Novel Agent in Colorectal Cancer: Approach to Individualized Therapy in Early Development

Clinical cancer research, 2010-06, Vol.16 (12), p.3193-3204

2010

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Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer

Molecular cancer therapeutics, 2010-12, Vol.9 (12), p.3351-3362

2010

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The Insulin-like Growth Factor I Receptor/Insulin Receptor Tyrosine Kinase Inhibitor PQIP Exhibits Enhanced Antitumor Effects in Combination with Chemotherapy Against Colorectal Cancer Models

Clinical cancer research, 2010-11, Vol.16 (22), p.5436-5446

2010

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The IGF-1R/IR Tyrosine Kinase Inhibitor, PQIP, Exhibits Enhanced Anti-Tumor Effects in Combination with Chemotherapy Against Colorectal Cancer Models

Clinical cancer research, 2010-10, Vol.16 (22), p.5436-5446

2010

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Abstract B226: Preclinical antitumor efficacy of the combination of the IGF-1R/IR dual kinase inhibitor OSI-906 with the MEK inhibitor selumetinib against colorectal cancer cell line and human tumor-derived xenografts

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.B226-B226

2011

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Abstract A38: Members of the noncanonical WNT pathway confer resistance to the MEK 1/2 inhibitor AZD6244 in colorectal cancer cell lines

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.A38-A38

2009

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Abstract A256: Rational combination of the IGF-1R/IR tyrosine kinase inhibitor (TKI), OSI-906, with the MEK inhibitor, U0126, results in synergistic and apoptotic effects in human colorectal cancer (CRC) cell lines

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.A256-A256

2009

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Abstract A39: Development and validation of an integrated genomic classifier to predict sensitivity to the IGF-1R/IR tyrosine kinase inhibitor, OSI-906, in colorectal cancer

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.A39-A39

2009

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RNA Interference Inhibits DUX4-induced Muscle Toxicity In Vivo: Implications for a Targeted FSHD Therapy

Molecular therapy, 2012-07, Vol.20 (7), p.1417-1423

2012

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Going to the Source: Discussions With Early and Mid-Career Faculty From Groups Underrepresented in Biomedical Research to Develop and Enhance CFAR Services

Journal of acquired immune deficiency syndromes (1999), 2023-10, Vol.94 (2S), p.S108-S115

2023

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Psychiatric predictors of quality of life in Parkinson's disease: A three-year longitudinal study

Journal of the neurological sciences, 2024-11, Vol.466, p.123248, Article 123248

2024

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Using a standardized algorithm to decrease central venous catheter utilization

American journal of infection control, 2024-06

2024

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Phenotypic Spectrum of Dystrophinopathy Due to Duchenne Muscular Dystrophy Exon 2 Duplications

Neurology, 2022-02, Vol.98 (7), p.e730

2022

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Cognitive Predictors of Quality of Life in Parkinson’s Disease: A Three-year Longitudinal Study (P4-3.018)

Neurology, 2024-04, Vol.102 (17_supplement_1)

2024

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Paired Interviews to Evaluate Patient and Proxy Responses on Patient Experience of Care Surveys (PECS)

Field methods, 2020-02, Vol.32 (1), p.105-126

2020

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Expression profiling of FSHD muscle supports a defect in specific stages of myogenic differentiation

Human molecular genetics, 2003-11, Vol.12 (22), p.2895-2907

2003

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Mother-Infant Dyad program in primary care: evidence-based postpartum care following gestational diabetes

The journal of maternal-fetal & neonatal medicine, 2022-01, Vol.35 (25), p.9336-9341

2022

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Mitochondrial DNA depletion syndrome due to mutations in the RRM2B gene

Neuromuscular disorders : NMD, 2008-06, Vol.18 (6), p.453-459

2008

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613. Lessons learned from a Rhode Island academic out-patient Lyme and tick-borne disease clinic

Open forum infectious diseases, 2020-12, Vol.7 (Supplement_1), p.S367-S367

2020

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Characterizing Post-treatment Lyme Disease Syndrome: A Mixed Methods Study of Patients at a Lyme Disease Clinic in Rhode Island

Rhode Island medical journal (2013), 2021-10, Vol.104 (8), p.30-34

2021

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Lessons Learned from a Rhode Island Academic Out-Patient Lyme and Tick-Borne Disease Clinic

Rhode Island medical journal (2013), 2020-12, Vol.103 (10), p.51-55

2020

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Association Study of Exon Variants in the NF-[kappa]B and TGF[Beta] Pathways Identifies CD40 as a Modifier of Duchenne Muscular Dystrophy

American journal of human genetics, 2016-11, Vol.99 (5), p.1163

2016

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Mental health in patients with advanced cancer at the end of life: evaluation of evidence and future directions

Expert review of quality of life in cancer care, 2018-05, Vol.3 (2-3), p.73-94

2018

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CS-JEDI: Required DEI Education, by CS PhD Students, for CS PhD Students

Proceedings of the 54th ACM Technical Symposium on Computer Science Education V. 1, 2023, p.87-93

2023

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Overcoming IGF1R/IR Resistance through Inhibition of MEK Signaling in Colorectal Cancer Models

Development of an Integrated Genomic Classifier for a Novel Agent in Colorectal Cancer: Approach to Individualized Therapy in Early Development

Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer

The Insulin-like Growth Factor I Receptor/Insulin Receptor Tyrosine Kinase Inhibitor PQIP Exhibits Enhanced Antitumor Effects in Combination with Chemotherapy Against Colorectal Cancer Models

The IGF-1R/IR Tyrosine Kinase Inhibitor, PQIP, Exhibits Enhanced Anti-Tumor Effects in Combination with Chemotherapy Against Colorectal Cancer Models

Abstract B226: Preclinical antitumor efficacy of the combination of the IGF-1R/IR dual kinase inhibitor OSI-906 with the MEK inhibitor selumetinib against colorectal cancer cell line and human tumor-derived xenografts

Abstract A38: Members of the noncanonical WNT pathway confer resistance to the MEK 1/2 inhibitor AZD6244 in colorectal cancer cell lines

Abstract A256: Rational combination of the IGF-1R/IR tyrosine kinase inhibitor (TKI), OSI-906, with the MEK inhibitor, U0126, results in synergistic and apoptotic effects in human colorectal cancer (CRC) cell lines

Abstract A39: Development and validation of an integrated genomic classifier to predict sensitivity to the IGF-1R/IR tyrosine kinase inhibitor, OSI-906, in colorectal cancer

RNA Interference Inhibits DUX4-induced Muscle Toxicity In Vivo: Implications for a Targeted FSHD Therapy

Going to the Source: Discussions With Early and Mid-Career Faculty From Groups Underrepresented in Biomedical Research to Develop and Enhance CFAR Services

Psychiatric predictors of quality of life in Parkinson's disease: A three-year longitudinal study

Using a standardized algorithm to decrease central venous catheter utilization

Phenotypic Spectrum of Dystrophinopathy Due to Duchenne Muscular Dystrophy Exon 2 Duplications

Cognitive Predictors of Quality of Life in Parkinson’s Disease: A Three-year Longitudinal Study (P4-3.018)

Paired Interviews to Evaluate Patient and Proxy Responses on Patient Experience of Care Surveys (PECS)

Expression profiling of FSHD muscle supports a defect in specific stages of myogenic differentiation

Mother-Infant Dyad program in primary care: evidence-based postpartum care following gestational diabetes

Mitochondrial DNA depletion syndrome due to mutations in the RRM2B gene

613. Lessons learned from a Rhode Island academic out-patient Lyme and tick-borne disease clinic

Characterizing Post-treatment Lyme Disease Syndrome: A Mixed Methods Study of Patients at a Lyme Disease Clinic in Rhode Island

Lessons Learned from a Rhode Island Academic Out-Patient Lyme and Tick-Borne Disease Clinic

Association Study of Exon Variants in the NF-[kappa]B and TGF[Beta] Pathways Identifies CD40 as a Modifier of Duchenne Muscular Dystrophy

Mental health in patients with advanced cancer at the end of life: evaluation of evidence and future directions

CS-JEDI: Required DEI Education, by CS PhD Students, for CS PhD Students

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