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Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405

PloS one, 2015-08, Vol.10 (8), p.e0135257-e0135257

2015

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RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity

PloS one, 2015-04, Vol.10 (4), p.e0122942

2015

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Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding

Biochimica et biophysica acta, 2016-11, Vol.1860 (11), p.2537-2552

2016

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The synthetic triterpenoid, RTA 405, increases the glomerular filtration rate and reduces angiotensin II–induced contraction of glomerular mesangial cells

Kidney international, 2013-05, Vol.83 (5), p.845-854

2013

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Omaveloxolone and TX63682 are hepatoprotective in the STAM mouse model of nonalcoholic steatohepatitis

Journal of biochemical and molecular toxicology, 2020-09, Vol.34 (9), p.e22526-n/a

2020

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Effects of Bardoxolone Methyl on Hepatic Enzymes in Patients with Type 2 Diabetes Mellitus and Stage 4 CKD

Clinical and translational science, 2021-01, Vol.14 (1), p.299-309

2021

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Evaluating the potential of Vacuolar ATPase inhibitors as anticancer agents and multigram synthesis of the potent salicylihalamide analog saliphenylhalamide

Bioorganic & medicinal chemistry, 2008-11, Vol.18 (22), p.5879-5883

2008

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A Phase I First-in-Human Trial of Bardoxolone Methyl in Patients with Advanced Solid Tumors and Lymphomas

Clinical cancer research, 2012-06, Vol.18 (12), p.3396-3406

2012

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Effect of Bardoxolone Methyl on Kidney Function in Patients with T2D and Stage 3b–4 CKD

American journal of nephrology, 2011-01, Vol.33 (5), p.469-476

2011

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Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1

American journal of physiology. Renal physiology, 2011-05, Vol.300 (5), p.F1180-F1192

2011

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A novel series of cysteine-dependent, allosteric inverse agonists of the nuclear receptor RORγt

Bioorganic & medicinal chemistry letters, 2020-03, Vol.30 (6), p.126967, Article 126967

2020

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Selective identification of secreted and transmembrane breast cancer markers using Escherichia coli ampicillin secretion trap

Cancer research (Chicago, Ill.), 2005-09, Vol.65 (18), p.8209-8217

2005

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205 Discovery and Development of Bardoxolone Methyl, an Antioxidant Inflammation Modulator (AIM) Targeting the KEAP1-NRF2 Pathway

American journal of kidney diseases, 2011, Vol.57 (4), p.B68-B68

2011

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319: Bardoxolone Methyl (BARD) Inhibits Inflammatory Signaling in Cultured Mesangial Cells

American journal of kidney diseases, 2010, Vol.55 (4), p.B111-B111

2010

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eXPRESSION: An in silico tool to predict patterns of gene expression

Gene Expression Patterns, 2005-06, Vol.5 (5), p.619-628

2005

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Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding

Biochimica et biophysica acta. General subjects, 2016-11, Vol.1860 (11 PA)

2016

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The synthetic triterpenoid, RTA405, increases glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells

Kidney international, 2012-12, Vol.83 (5), p.845-854

2012

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RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity: e0122942

PloS one, 2015-04, Vol.10 (4)

2015

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Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPAR[gamma], and HO-1

American journal of physiology. Renal physiology, 2011-05, Vol.300 (5), p.F1180

2011

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Systemic hemodynamic, neurohormonal, and renal effects of a steady-state infusion of human brain natriuretic peptide in patients with hemodynamically decompensated heart failure

Journal of cardiac failure, 1998-03, Vol.4 (1), p.37-44

1998

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Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1

American journal of physiology. Renal physiology, 2011, Vol.69 (5)

2011

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Reading the fine print of the human genome

IEEE engineering in medicine and biology magazine, 2003-03, Vol.22 (2), p.105-108

2003

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ChemInform Abstract: Evaluating the Potential of Vacuolar ATPase Inhibitors as Anticancer Agents and Multigram Synthesis of the Potent Salicylihalamide Analogue Saliphenylhalamide (V)

ChemInform, 2009-04, Vol.40 (14), p.no-no

2009

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Optimizing the placement of numerical relativity simulations using a mismatch predicting neural network

Physical review. D, 2023-01, Vol.107 (2), Article 024034

Ferguson, Deborah

2023

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Distribution of Surface Plastic Debris in the Eastern Pacific Ocean from an 11-Year Data Set

Environmental science & technology, 2014-05, Vol.48 (9), p.4732-4738

2014

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Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity

Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding

The synthetic triterpenoid, RTA 405, increases the glomerular filtration rate and reduces angiotensin II–induced contraction of glomerular mesangial cells

Omaveloxolone and TX63682 are hepatoprotective in the STAM mouse model of nonalcoholic steatohepatitis

Effects of Bardoxolone Methyl on Hepatic Enzymes in Patients with Type 2 Diabetes Mellitus and Stage 4 CKD

Evaluating the potential of Vacuolar ATPase inhibitors as anticancer agents and multigram synthesis of the potent salicylihalamide analog saliphenylhalamide

A Phase I First-in-Human Trial of Bardoxolone Methyl in Patients with Advanced Solid Tumors and Lymphomas

Effect of Bardoxolone Methyl on Kidney Function in Patients with T2D and Stage 3b–4 CKD

Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1

A novel series of cysteine-dependent, allosteric inverse agonists of the nuclear receptor RORγt

Selective identification of secreted and transmembrane breast cancer markers using Escherichia coli ampicillin secretion trap

205 Discovery and Development of Bardoxolone Methyl, an Antioxidant Inflammation Modulator (AIM) Targeting the KEAP1-NRF2 Pathway

319: Bardoxolone Methyl (BARD) Inhibits Inflammatory Signaling in Cultured Mesangial Cells

eXPRESSION: An in silico tool to predict patterns of gene expression

Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding

The synthetic triterpenoid, RTA405, increases glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity: e0122942

Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPAR[gamma], and HO-1

Systemic hemodynamic, neurohormonal, and renal effects of a steady-state infusion of human brain natriuretic peptide in patients with hemodynamically decompensated heart failure

Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1

Reading the fine print of the human genome

ChemInform Abstract: Evaluating the Potential of Vacuolar ATPase Inhibitors as Anticancer Agents and Multigram Synthesis of the Potent Salicylihalamide Analogue Saliphenylhalamide (V)

Optimizing the placement of numerical relativity simulations using a mismatch predicting neural network

Distribution of Surface Plastic Debris in the Eastern Pacific Ocean from an 11-Year Data Set

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