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Building strong bones: molecular regulation of the osteoblast lineage

Nature reviews. Molecular cell biology, 2012-01, Vol.13 (1), p.27-38

Long, Fanxin

2012

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Wnt signaling and cellular metabolism in osteoblasts

Cellular and molecular life sciences : CMLS, 2017-05, Vol.74 (9), p.1649-1657

2017

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Hedgehog signaling via Gli2 prevents obesity induced by high-fat diet in adult mice

eLife, 2017-12, Vol.6

2017

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Glucose metabolism in skeletal cells

Bone Reports, 2022-12, Vol.17, p.101640, Article 101640

Long, Fanxin

2022

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mTORC1 Signaling Promotes Osteoblast Differentiation from Preosteoblasts

PloS one, 2015-06, Vol.10 (6), p.e0130627-e0130627

2015

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mTOR signaling in skeletal development and disease

Bone Research, 2018-01, Vol.6 (1), p.1-6, Article 1

2018

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mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis

Development (Cambridge), 2014-07, Vol.141 (14), p.2848-2854

2014

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Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways

PLoS genetics, 2021-01, Vol.17 (1), p.e1009233-e1009233

2021

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Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts

PLoS genetics, 2020-11, Vol.16 (11), p.e1009169-e1009169

2020

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Energy Metabolism of the Osteoblast: Implications for Osteoporosis

Endocrine reviews, 2017-06, Vol.38 (3), p.255-266

2017

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Gli1 identifies osteogenic progenitors for bone formation and fracture repair

Nature communications, 2017-12, Vol.8 (1), p.2043-12, Article 2043

2017

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Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

eLife, 2020-04, Vol.9

2020

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Glucose metabolism induced by Bmp signaling is essential for murine skeletal development

Nature communications, 2018-11, Vol.9 (1), p.4831-11, Article 4831

2018

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Enthesis fibrocartilage cells originate from a population of Hedgehog-responsive cells modulated by the loading environment

Development (Cambridge), 2015-01, Vol.142 (1), p.196-206

2015

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Functional interaction between Wnt and Bmp signaling in periosteal bone growth

Scientific reports, 2021-05, Vol.11 (1), p.10782-10782, Article 10782

2021

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Both aerobic glycolysis and mitochondrial respiration are required for osteoclast differentiation

The FASEB journal, 2020-08, Vol.34 (8), p.11058-11067

2020

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Transcriptional programs of Pitx2 and Tfap2a/Tfap2b controlling lineage specification of mandibular epithelium during tooth initiation

PLoS genetics, 2024-07, Vol.20 (7), p.e1011364

2024

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PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling

Journal of bone and mineral research, 2015-11, Vol.30 (11), p.1959-1968

2015

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The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization

Development (Cambridge), 2009-12, Vol.136 (24), p.4177-4185

2009

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Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice

PloS one, 2014-01, Vol.9 (1), p.e85161-e85161

2014

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Heads, Shoulders, Elbows, Knees, and Toes: Modular Gdf5 Enhancers Control Different Joints in the Vertebrate Skeleton

PLoS genetics, 2016-11, Vol.12 (11), p.e1006454-e1006454

2016

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wnt16 regulates spine and muscle morphogenesis through parallel signals from notochord and dermomyotome

PLoS genetics, 2022-11, Vol.18 (11), p.e1010496-e1010496

2022

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Osteoblast-intrinsic defect in glucose metabolism impairs bone formation in type II diabetic male mice

eLife, 2023-05, Vol.12

2023

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WNT-LRP5 Signaling Induces Warburg Effect through mTORC2 Activation during Osteoblast Differentiation

Cell metabolism, 2013-05, Vol.17 (5), p.745-755

2013

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Lhx6 regulates canonical Wnt signaling to control the fate of mesenchymal progenitor cells during mouse molar root patterning

PLoS genetics, 2021-02, Vol.17 (2), p.e1009320-e1009320

2021

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Building strong bones: molecular regulation of the osteoblast lineage

Wnt signaling and cellular metabolism in osteoblasts

Hedgehog signaling via Gli2 prevents obesity induced by high-fat diet in adult mice

Glucose metabolism in skeletal cells

mTORC1 Signaling Promotes Osteoblast Differentiation from Preosteoblasts

mTOR signaling in skeletal development and disease

mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis

Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways

Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts

Energy Metabolism of the Osteoblast: Implications for Osteoporosis

Gli1 identifies osteogenic progenitors for bone formation and fracture repair

Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

Glucose metabolism induced by Bmp signaling is essential for murine skeletal development

Enthesis fibrocartilage cells originate from a population of Hedgehog-responsive cells modulated by the loading environment

Functional interaction between Wnt and Bmp signaling in periosteal bone growth

Both aerobic glycolysis and mitochondrial respiration are required for osteoclast differentiation

Transcriptional programs of Pitx2 and Tfap2a/Tfap2b controlling lineage specification of mandibular epithelium during tooth initiation

PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling

The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization

Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice

Heads, Shoulders, Elbows, Knees, and Toes: Modular Gdf5 Enhancers Control Different Joints in the Vertebrate Skeleton

wnt16 regulates spine and muscle morphogenesis through parallel signals from notochord and dermomyotome

Osteoblast-intrinsic defect in glucose metabolism impairs bone formation in type II diabetic male mice

WNT-LRP5 Signaling Induces Warburg Effect through mTORC2 Activation during Osteoblast Differentiation

Lhx6 regulates canonical Wnt signaling to control the fate of mesenchymal progenitor cells during mouse molar root patterning

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