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Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders

Journal of medicinal chemistry, 2018-10, Vol.61 (20), p.9062-9084

2018

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Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome

PloS one, 2014-12, Vol.9 (12), p.e114521

2014

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Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain

The Journal of cell biology, 2005-08, Vol.170 (3), p.477-485

2005

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Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli

Nature (London), 2002-04, Vol.416 (6881), p.644-648

2002

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The Role of the Mannose-Binding Lectin in Innate Immunity

Clinical infectious diseases, 2005-11, Vol.41 (Supplement-7), p.S440-S444

2005

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Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila

Science (American Association for the Advancement of Science), 1999-06, Vol.284 (5422), p.1991-1994

1999

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Activation of the Lectin Pathway by Natural IgM in a Model of Ischemia/Reperfusion Injury

Journal of Immunology, 2006-10, Vol.177 (7), p.4727-4734

2006

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Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila

Cell, 2005-10, Vol.123 (2), p.335-346

2005

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Mannose-binding lectin regulates host resistance and pathology during experimental infection with Trypanosoma cruzi

PloS one, 2012-11, Vol.7 (11), p.e47835-e47835

2012

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Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome

The Journal of experimental medicine, 2008-01, Vol.205 (1), p.169-181

2008

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Reduced tissue damage and improved recovery of motor function after traumatic brain injury in mice deficient in complement component C4

Journal of cerebral blood flow and metabolism, 2007-12, Vol.27 (12), p.1954-1964

2007

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Mannose-Binding Lectin-Deficient Mice Display Defective Apoptotic Cell Clearance but No Autoimmune Phenotype

The Journal of immunology (1950), 2005-03, Vol.174 (6), p.3220-3226

2005

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The mannose-binding lectin: a prototypic pattern recognition molecule

Current Opinion in Immunology, 2006-02, Vol.18 (1), p.16-23

2006

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Interferon Alfa-2a Therapy for Life-Threatening Hemangiomas of Infancy

The New England journal of medicine, 1992-05, Vol.326 (22), p.1456-1463

1992

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Mannose-Binding Lectin Is a Regulator of Inflammation That Accompanies Myocardial Ischemia and Reperfusion Injury

The Journal of immunology (1950), 2005-07, Vol.175 (1), p.541-546

2005

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The mannose receptor is a pattern recognition receptor involved in host defense

Current opinion in immunology, 1998-02, Vol.10 (1), p.50-55

1998

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High-Dose Mannose-Binding Lectin Therapy for Ebola Virus Infection

The Journal of infectious diseases, 2011-01, Vol.203 (2), p.175-179

2011

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Deficiency of mannose-binding lectin greatly increases antibody response in a mouse model of vaccination

Clinical immunology (Orlando, Fla.), 2009-03, Vol.130 (3), p.264-271

2009

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Relative Roles of Complement Factor 3 and Mannose-Binding Lectin in Host Defense against Infection

Infection and Immunity, 2005-12, Vol.73 (12), p.8188-8193

2005

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Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity

Blood, 2005-10, Vol.106 (7), p.2551-2558

2005

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Phagocytosis: elegant complexity

Immunity (Cambridge, Mass.), 2005-05, Vol.22 (5), p.539-550

2005

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Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors

PloS one, 2013-04, Vol.8 (4), p.e60838-e60838

2013

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Deficiency of Mannose-Binding Lectin Greatly Increases Susceptibility to Postburn Infection with Pseudomonas aeruginosa

Journal of Immunology, 2006-02, Vol.176 (3), p.1769-1775

2006

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Mannan-Binding Lectin Enhances Susceptibility to Visceral Leishmaniasis

Infection and Immunity, 2001-08, Vol.69 (8), p.5212-5215

2001

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Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila

Microbes and infection, 2003-08, Vol.5 (10), p.815-824

2003

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Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders

Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome

Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain

Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli

The Role of the Mannose-Binding Lectin in Innate Immunity

Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila

Activation of the Lectin Pathway by Natural IgM in a Model of Ischemia/Reperfusion Injury

Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila

Mannose-binding lectin regulates host resistance and pathology during experimental infection with Trypanosoma cruzi

Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome

Reduced tissue damage and improved recovery of motor function after traumatic brain injury in mice deficient in complement component C4

Mannose-Binding Lectin-Deficient Mice Display Defective Apoptotic Cell Clearance but No Autoimmune Phenotype

The mannose-binding lectin: a prototypic pattern recognition molecule

Interferon Alfa-2a Therapy for Life-Threatening Hemangiomas of Infancy

Mannose-Binding Lectin Is a Regulator of Inflammation That Accompanies Myocardial Ischemia and Reperfusion Injury

The mannose receptor is a pattern recognition receptor involved in host defense

High-Dose Mannose-Binding Lectin Therapy for Ebola Virus Infection

Deficiency of mannose-binding lectin greatly increases antibody response in a mouse model of vaccination

Relative Roles of Complement Factor 3 and Mannose-Binding Lectin in Host Defense against Infection

Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity

Phagocytosis: elegant complexity

Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors

Deficiency of Mannose-Binding Lectin Greatly Increases Susceptibility to Postburn Infection with Pseudomonas aeruginosa

Mannan-Binding Lectin Enhances Susceptibility to Visceral Leishmaniasis

Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila

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