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In vivo MR in the drug pipeline

Journal of magnetic resonance (1997), 2018-07, Vol.292, p.117-128

Evelhoch, Jeffrey L.

2018

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Quantitative magnetic resonance imaging phantoms: A review and the need for a system phantom

Magnetic resonance in medicine, 2018-01, Vol.79 (1), p.48-61

2018

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Imaging biomarker roadmap for cancer studies

Nature reviews. Clinical oncology, 2017-03, Vol.14 (3), p.169-186

2017

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A standard system phantom for magnetic resonance imaging

Magnetic resonance in medicine, 2021-09, Vol.86 (3), p.1194-1211

2021

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Safety, Pharmacokinetics, and Antitumor Activity of AMG 386, a Selective Angiopoietin Inhibitor, in Adult Patients With Advanced Solid Tumors

Journal of clinical oncology, 2009-07, Vol.27 (21), p.3557-3565

2009

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fMRI study of olfactory processing in mice under three anesthesia protocols: Insight into the effect of ketamine on olfactory processing

NeuroImage (Orlando, Fla.), 2020-06, Vol.213, p.116725-116725, Article 116725

2020

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fMRI study of the role of glutamate NMDA receptor in the olfactory processing in monkeys

PloS one, 2018-06, Vol.13 (6), p.e0198395-e0198395

2018

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Investigation of cross-species translatability of pharmacological MRI in awake nonhuman primate - a buprenorphine challenge study

PloS one, 2014-10, Vol.9 (10), p.e110432-e110432

2014

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Distinct BOLD fMRI Responses of Capsaicin-Induced Thermal Sensation Reveal Pain-Related Brain Activation in Nonhuman Primates

PloS one, 2016-06, Vol.11 (6), p.e0156805-e0156805

2016

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Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Pharmacodynamic Measure of Response After Acute Dosing of AG-013736, an Oral Angiogenesis Inhibitor, in Patients With Advanced Solid Tumors: Results From a Phase I Study

Journal of clinical oncology, 2005-08, Vol.23 (24), p.5464-5473

2005

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Characterization of regional left ventricular function in nonhuman primates using magnetic resonance imaging biomarkers: a test-retest repeatability and inter-subject variability study

PloS one, 2015-05, Vol.10 (5), p.e0127947-e0127947

2015

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Test–retest reliability of evoked heat stimulation BOLD fMRI

Journal of neuroscience methods, 2015-09, Vol.253, p.38-46

2015

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fMRI study of olfaction in the olfactory bulb and high olfactory structures of rats: Insight into their roles in habituation

NeuroImage (Orlando, Fla.), 2016-02, Vol.127, p.445-455

2016

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In Vivo Evaluation and Dosimetry Estimate for a High Affinity Affibody PET Tracer Targeting PD-L1

Molecular imaging and biology, 2021-04, Vol.23 (2), p.241-249

2021

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Imaging Beta-Cell Function in the Pancreas of Non-Human Primates Using a Zinc-Sensitive MRI Contrast Agent

Frontiers in endocrinology (Lausanne), 2021-05, Vol.12, p.641722-641722

2021

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Functional imaging of olfaction by CBV fMRI in monkeys: Insight into the role of olfactory bulb in habituation

NeuroImage (Orlando, Fla.), 2015-02, Vol.106, p.364-372

2015

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Evaluation of an fMRI USPIO‐based assay in healthy human volunteers

Journal of magnetic resonance imaging, 2017-07, Vol.46 (1), p.124-133

2017

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Recommendations towards standards for quantitative MRI (qMRI) and outstanding needs

Journal of magnetic resonance imaging, 2019-06, Vol.49 (7), p.e26-e39

2019

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Quantification of regional myocardial mean intracellular water lifetime: A nonhuman primate study in myocardial stress

NMR in biomedicine, 2020-04, Vol.33 (4), p.e4248-n/a

2020

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Discovery of [11C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors

Bioorganic & medicinal chemistry letters, 2015-11, Vol.25 (21), p.4893-4898

2015

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fMRI study of the role of glutamate NMDA receptor in the olfactory adaptation in rats: Insights into cellular and molecular mechanisms of olfactory adaptation

NeuroImage (Orlando, Fla.), 2017-04, Vol.149, p.348-360

2017

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Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine

NeuroImage (Orlando, Fla.), 2012-02, Vol.59 (4), p.3762-3773

2012

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Brain Imaging of Alzheimer Dementia Patients and Elderly Controls with 18 F-MK-6240, a PET Tracer Targeting Neurofibrillary Tangles

Journal of Nuclear Medicine, 2019-01, Vol.60 (1), p.107-114

2019

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Quantitative MRI biomarkers to characterize regional left ventricular perfusion and function in nonhuman primates during dobutamine‐induced stress: A reproducibility and reliability study

Journal of magnetic resonance imaging, 2017-02, Vol.45 (2), p.556-569

2017

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In vivo MR in the drug pipeline

Quantitative magnetic resonance imaging phantoms: A review and the need for a system phantom

Discovery of 6‑(Fluoro-18 F)‑3-(1H‑pyrrolo[2,3‑c]pyridin-1-yl)isoquinolin-5-amine ([18F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs)

Imaging biomarker roadmap for cancer studies

A standard system phantom for magnetic resonance imaging

Safety, Pharmacokinetics, and Antitumor Activity of AMG 386, a Selective Angiopoietin Inhibitor, in Adult Patients With Advanced Solid Tumors

fMRI study of olfactory processing in mice under three anesthesia protocols: Insight into the effect of ketamine on olfactory processing

fMRI study of the role of glutamate NMDA receptor in the olfactory processing in monkeys

Investigation of cross-species translatability of pharmacological MRI in awake nonhuman primate - a buprenorphine challenge study

Distinct BOLD fMRI Responses of Capsaicin-Induced Thermal Sensation Reveal Pain-Related Brain Activation in Nonhuman Primates

Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Pharmacodynamic Measure of Response After Acute Dosing of AG-013736, an Oral Angiogenesis Inhibitor, in Patients With Advanced Solid Tumors: Results From a Phase I Study

Characterization of regional left ventricular function in nonhuman primates using magnetic resonance imaging biomarkers: a test-retest repeatability and inter-subject variability study

Test–retest reliability of evoked heat stimulation BOLD fMRI

fMRI study of olfaction in the olfactory bulb and high olfactory structures of rats: Insight into their roles in habituation

In Vivo Evaluation and Dosimetry Estimate for a High Affinity Affibody PET Tracer Targeting PD-L1

Imaging Beta-Cell Function in the Pancreas of Non-Human Primates Using a Zinc-Sensitive MRI Contrast Agent

Functional imaging of olfaction by CBV fMRI in monkeys: Insight into the role of olfactory bulb in habituation

Evaluation of an fMRI USPIO‐based assay in healthy human volunteers

Recommendations towards standards for quantitative MRI (qMRI) and outstanding needs

Quantification of regional myocardial mean intracellular water lifetime: A nonhuman primate study in myocardial stress

Discovery of [11C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors

fMRI study of the role of glutamate NMDA receptor in the olfactory adaptation in rats: Insights into cellular and molecular mechanisms of olfactory adaptation

Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine

Brain Imaging of Alzheimer Dementia Patients and Elderly Controls with 18 F-MK-6240, a PET Tracer Targeting Neurofibrillary Tangles

Quantitative MRI biomarkers to characterize regional left ventricular perfusion and function in nonhuman primates during dobutamine‐induced stress: A reproducibility and reliability study

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