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Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling

Cell, 2014-04, Vol.157 (2), p.357-368

2014

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Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition

Molecular cell, 2019-03, Vol.73 (5), p.1015-1027.e7

2019

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Low-affinity CD4+ T cells are major responders in the primary immune response

Nature communications, 2016-12, Vol.7 (1), p.13848-13848, Article 13848

2016

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Force in Immunology: There Is Often a Catch

The Journal of immunology (1950), 2023-08, Vol.211 (3), p.307-307

Evavold, Brian D

2023

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Relationship of 2D Affinity to T Cell Functional Outcomes

International journal of molecular sciences, 2020-10, Vol.21 (21), p.7969

2020

Volltextzugriff (PDF)

Targeted loss of SHP1 in murine thymocytes dampens TCR signaling late in selection

European journal of immunology, 2016-09, Vol.46 (9), p.2103-2110

2016

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2D Kinetic Analysis of TCR and CD8 Coreceptor for LCMV GP33 Epitopes

Frontiers in immunology, 2018-10, Vol.9, p.2348-2348

2018

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PD-1 Dynamically Regulates Inflammation and Development of Brain-Resident Memory CD8 T Cells During Persistent Viral Encephalitis

Frontiers in immunology, 2019-04, Vol.10, p.783-783

2019

Volltextzugriff (PDF)

T Cell Receptor-Major Histocompatibility Complex Interaction Strength Defines Trafficking and CD103 + Memory Status of CD8 T Cells in the Brain

Frontiers in immunology, 2018-06, Vol.9, p.1290

2018

Volltextzugriff (PDF)

CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence

Cell reports (Cambridge), 2020-02, Vol.30 (5), p.1282-1291.e5

2020

Volltextzugriff (PDF)

Viral Escape Mutant Epitope Maintains TCR Affinity for Antigen yet Curtails CD8 T Cell Responses

PloS one, 2016-02, Vol.11 (2), p.e0149582-e0149582

2016

Volltextzugriff (PDF)

Specificity, magnitude, and kinetics of MOG‐specific CD8+ T cell responses during experimental autoimmune encephalomyelitis

European journal of immunology, 2005-01, Vol.35 (1), p.76-85

2005

Volltextzugriff (PDF)

Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics

PloS one, 2012-03, Vol.7 (3), p.e32562-e32562

2012

Volltextzugriff (PDF)

A TCR mechanotransduction signaling loop induces negative selection in the thymus

Nature immunology, 2018-12, Vol.19 (12), p.1379

2018

Volltextzugriff (PDF)

Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope

Frontiers in immunology, 2017-11, Vol.8, p.1503-1503

2017

Volltextzugriff (PDF)

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding

Cell, 2018-07, Vol.174 (3), p.672-687.e27

2018

Volltextzugriff (PDF)

Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells

The Journal of immunology (1950), 2015-10, Vol.195 (8), p.3557-3564

2015

Volltextzugriff (PDF)

Tuning T cell receptor sensitivity through catch bond engineering

Science (American Association for the Advancement of Science), 2022-04, Vol.376 (6589), p.eabl5282-eabl5282

2022

Volltextzugriff (PDF)

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells

Science (American Association for the Advancement of Science), 2018-09, Vol.361 (6407)

2018

Volltextzugriff (PDF)

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness

Nature (London), 2010-04, Vol.464 (7290), p.932-936

2010

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High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses

The Journal of experimental medicine, 2011-01, Vol.208 (1), p.81-90

2011

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What's the Catch? The Significance of Catch Bonds in T Cell Activation

The Journal of immunology (1950), 2023-08, Vol.211 (3), p.333-342

2023

Volltextzugriff (PDF)

Cutting Edge: Resident Memory CD8 T Cells Express High-Affinity TCRs

The Journal of immunology (1950), 2015-10, Vol.195 (8), p.3520-3524

2015

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Ratiometric Tension Probes for Mapping Receptor Forces and Clustering at Intermembrane Junctions

Nano letters, 2016-07, Vol.16 (7), p.4552-4559

2016

Volltextzugriff (PDF)

Understanding TCR affinity, antigen specificity, and cross-reactivity to improve TCR gene-modified T cells for cancer immunotherapy

Cancer Immunology, Immunotherapy, 2019-11, Vol.68 (11), p.1881-1889

2019

Volltextzugriff (PDF)

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Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling

Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition

Low-affinity CD4+ T cells are major responders in the primary immune response

Force in Immunology: There Is Often a Catch

Relationship of 2D Affinity to T Cell Functional Outcomes

Targeted loss of SHP1 in murine thymocytes dampens TCR signaling late in selection

2D Kinetic Analysis of TCR and CD8 Coreceptor for LCMV GP33 Epitopes

PD-1 Dynamically Regulates Inflammation and Development of Brain-Resident Memory CD8 T Cells During Persistent Viral Encephalitis

T Cell Receptor-Major Histocompatibility Complex Interaction Strength Defines Trafficking and CD103 + Memory Status of CD8 T Cells in the Brain

CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence

Viral Escape Mutant Epitope Maintains TCR Affinity for Antigen yet Curtails CD8 T Cell Responses

Specificity, magnitude, and kinetics of MOG‐specific CD8+ T cell responses during experimental autoimmune encephalomyelitis

Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics

A TCR mechanotransduction signaling loop induces negative selection in the thymus

Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding

Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells

Tuning T cell receptor sensitivity through catch bond engineering

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness

High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses

What's the Catch? The Significance of Catch Bonds in T Cell Activation

Cutting Edge: Resident Memory CD8 T Cells Express High-Affinity TCRs

Ratiometric Tension Probes for Mapping Receptor Forces and Clustering at Intermembrane Junctions

Understanding TCR affinity, antigen specificity, and cross-reactivity to improve TCR gene-modified T cells for cancer immunotherapy

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