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TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis

Autophagy, 2018-04, Vol.14 (4), p.724-726

2018

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ATP biosensor reveals microbial energetic dynamics and facilitates bioproduction

Nature communications, 2024-06, Vol.15 (1), p.5299-10, Article 5299

2024

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Classical and alternative roles for autophagy in lipid metabolism

Current opinion in lipidology, 2018-06, Vol.29 (3), p.203-211

2018

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p62/ SQSTM1 and Selective Autophagy in Cardiometabolic Diseases

Antioxidants & redox signaling, 2019-08, Vol.31 (6), p.458-471

2019

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Bacterial metabolic heterogeneity: origins and applications in engineering and infectious disease

Current opinion in biotechnology, 2020-08, Vol.64, p.183-189

2020

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Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

Nature communications, 2017-06, Vol.8 (1), p.15750-15750, Article 15750

2017

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Target acquired: Selective autophagy in cardiometabolic disease

Science signaling, 2017-02, Vol.10 (468)

2017

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Degradation and beyond: the macrophage lysosome as a nexus for nutrient sensing and processing in atherosclerosis

Current opinion in lipidology, 2015-10, Vol.26 (5), p.394-404

2015

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Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response

Autophagy, 2021-11, Vol.17 (11), p.3740-3752

2021

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Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis

Science signaling, 2016-01, Vol.9 (409), p.ra2

2016

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TFEB drives PGC-1α expression in adipocytes to protect against diet-induced metabolic dysfunction

Science signaling, 2019-11, Vol.12 (606)

2019

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Loss of Macrophage mTORC2 Drives Atherosclerosis via FoxO1 and IL-1β Signaling

Circulation research, 2023-07, Vol.133 (3), p.200-219

2023

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Modulating Oxysterol Sensing to Control Macrophage Apoptosis and Atherosclerosis

Circulation research, 2016-12, Vol.119 (12), p.1258-1261

2016

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TFEB is a master regulator of tumor-associated macrophages in breast cancer

Journal for immunotherapy of cancer, 2020-06, Vol.8 (1), p.e000543

2020

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Functional Characterization of LIPA (Lysosomal Acid Lipase) Variants Associated With Coronary Artery Disease

Arteriosclerosis, thrombosis, and vascular biology, 2019-12, Vol.39 (12), p.2480-2491

2019

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Transcriptional factor EB regulates macrophage polarization in the tumor microenvironment

Oncoimmunology, 2017-05, Vol.6 (5), p.e1312042-e1312042

2017

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High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy

Nature metabolism, 2020-01, Vol.2 (1), p.110-125

2020

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Hypoxia in Plaque Macrophages: A New Danger Signal for Interleukin-1β Activation?

Circulation research, 2014-10, Vol.115 (10), p.817-820

2014

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A shift in energy metabolism anticipates the onset of sarcopenia in rhesus monkeys

Aging cell, 2013-08, Vol.12 (4), p.672-681

2013

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Effects of sodium nitrite supplementation on vascular function and related small metabolite signatures in middle-aged and older adults

Journal of applied physiology (1985), 2016-02, Vol.120 (4), p.416-425

2016

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Cellular adaptation contributes to calorie restriction-induced preservation of skeletal muscle in aged rhesus monkeys

Experimental gerontology, 2012-03, Vol.47 (3), p.229-236

2012

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Applications and advances of metabolite biosensors for metabolic engineering

Metabolic engineering, 2015-09, Vol.31, p.35-43

2015

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Improved motor and cognitive performance with sodium nitrite supplementation is related to small metabolite signatures: a pilot trial in middle-aged and older adults

Aging (Albany, NY.), 2015-11, Vol.7 (11), p.1004-1021

2015

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Late-life voluntary wheel running reverses age-related aortic stiffness in mice: a translational model for studying mechanisms of exercise-mediated arterial de-stiffening

GeroScience, 2021-02, Vol.43 (1), p.423-432

2021

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Preserved Microvascular Endothelial Function in Young, Obese Adults with Functional Loss of Nitric Oxide Signaling

Frontiers in physiology, 2015-12, Vol.6, p.387-387

2015

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TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis

ATP biosensor reveals microbial energetic dynamics and facilitates bioproduction

Classical and alternative roles for autophagy in lipid metabolism

p62/ SQSTM1 and Selective Autophagy in Cardiometabolic Diseases

Bacterial metabolic heterogeneity: origins and applications in engineering and infectious disease

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

Target acquired: Selective autophagy in cardiometabolic disease

Degradation and beyond: the macrophage lysosome as a nexus for nutrient sensing and processing in atherosclerosis

Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response

Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis

TFEB drives PGC-1α expression in adipocytes to protect against diet-induced metabolic dysfunction

Loss of Macrophage mTORC2 Drives Atherosclerosis via FoxO1 and IL-1β Signaling

Modulating Oxysterol Sensing to Control Macrophage Apoptosis and Atherosclerosis

TFEB is a master regulator of tumor-associated macrophages in breast cancer

Functional Characterization of LIPA (Lysosomal Acid Lipase) Variants Associated With Coronary Artery Disease

Transcriptional factor EB regulates macrophage polarization in the tumor microenvironment

High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy

Hypoxia in Plaque Macrophages: A New Danger Signal for Interleukin-1β Activation?

A shift in energy metabolism anticipates the onset of sarcopenia in rhesus monkeys

Effects of sodium nitrite supplementation on vascular function and related small metabolite signatures in middle-aged and older adults

Cellular adaptation contributes to calorie restriction-induced preservation of skeletal muscle in aged rhesus monkeys

Applications and advances of metabolite biosensors for metabolic engineering

Improved motor and cognitive performance with sodium nitrite supplementation is related to small metabolite signatures: a pilot trial in middle-aged and older adults

Late-life voluntary wheel running reverses age-related aortic stiffness in mice: a translational model for studying mechanisms of exercise-mediated arterial de-stiffening

Preserved Microvascular Endothelial Function in Young, Obese Adults with Functional Loss of Nitric Oxide Signaling

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