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Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR−/− and apoE−/− mice

Journal of lipid research, 2009-06, Vol.50 (6), p.1090-1100

2009

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LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse[S]

Journal of lipid research, 2009-12, Vol.50 (12), p.2358-2370

2009

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A synthetic farnesoid X receptor (FXR) agonist promotes cholesterol lowering in models of dyslipidemia

American journal of physiology: Gastrointestinal and liver physiology, 2009-03, Vol.296 (3), p.G543-G552

2009

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Loss of small heterodimer partner expression in the liver protects against dyslipidemia

Journal of lipid research, 2009-02, Vol.50 (2), p.193-203

2009

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The Nuclear Hormone Receptor Farnesoid X Receptor (FXR) Is Activated by Androsterone

Endocrinology (Philadelphia), 2006-09, Vol.147 (9), p.4025-4033

2006

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Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells

Journal of translational medicine, 2008-10, Vol.6 (1), p.59-59, Article 59

2008

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Bile acid signaling through FXR induces intracellular adhesion molecule-1 expression in mouse liver and human hepatocytes

American journal of physiology: Gastrointestinal and liver physiology, 2005-08, Vol.289 (2), p.G267-G273

2005

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The Chemist's Companion Guide to Patent Law

1. Aufl., 2010

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Inhibition of the CaM-Kinases augments cell death in response to oxygen radicals and oxygen radical inducing cancer therapies in MCF-7 human breast cancer cells

Cancer biology & therapy, 2006-08, Vol.5 (8), p.1022-1030

2006

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Indazole-Based Liver X Receptor (LXR) Modulators with Maintained Atherosclerotic Lesion Reduction Activity but Diminished Stimulation of Hepatic Triglyceride Synthesis

Journal of medicinal chemistry, 2008-11, Vol.51 (22), p.7161-7168

2008

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Circulating Cytokine Levels in Prostate Cancer Patients Undergoing Radiation Therapy: Influence of Neoadjuvant Total Androgen Suppression

In vivo (Athens), 2009-09, Vol.23 (5), p.827-833

2009

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Reciprocal Antagonism Between Estrogen Receptor and NF-κB Activity In Vivo

Circulation research, 2001-10, Vol.89 (9), p.823-830

2001

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Identification of Phenylsulfone-Substituted Quinoxaline (WYE-672) as a Tissue Selective Liver X-receptor (LXR) Agonist

Journal of medicinal chemistry, 2010-04, Vol.53 (8), p.3296-3304

2010

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Improvement of Physiochemical Properties of the Tetrahydroazepinoindole Series of Farnesoid X Receptor (FXR) Agonists: Beneficial Modulation of Lipids in Primates

Journal of medicinal chemistry, 2010-02, Vol.53 (4), p.1774-1787

2010

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Response of T Lymphocyte Populations in Prostate Cancer Patients Undergoing Radiotherapy: Influence of Neoajuvant Total Androgen Suppression

Anticancer research, 2005-07, Vol.25 (4), p.3159-3166

2005

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Estrogen Receptor α Regulates Expression of the Orphan Receptor Small Heterodimer Partner

The Journal of biological chemistry, 2003-09, Vol.278 (38), p.36418-36429

2003

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Pyrrole[2,3- d]azepino compounds as agonists of the farnesoid X receptor (FXR)

Bioorganic & medicinal chemistry letters, 2009-09, Vol.19 (18), p.5289-5292

2009

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Loss of small heterodimer partner expression in the liver protects against dyslipidemias

Journal of lipid research, 2009-02, Vol.50 (2), p.193-203

2009

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Estrogen Receptor α Inhibits IL-1β Induction of Gene Expression in the Mouse Liver

Endocrinology (Philadelphia), 2002-07, Vol.143 (7), p.2559-2570

2002

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Global Transcription Profiling of Estrogen Activity: Estrogen Receptor α Regulates Gene Expression in the Kidney

Endocrinology (Philadelphia), 2003-02, Vol.144 (2), p.701-710

2003

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346 Increased Hepatic Bile Acid (BA) Synthesis Prevents Cholesterol Gallstones in Small Heterodimer Partner (SHP) Knockout Mice

Gastroenterology (New York, N.Y. 1943), 2009, Vol.136 (5), p.A-800-A-800

2009

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Inhibition of complement activity by humanized anti-C5 antibody and single-chain Fv

Molecular immunology, 1996-12, Vol.33 (17), p.1389-1401

1996

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Farnesoid X receptor as a therapeutic target for dyslipidemia

Clinical lipidology, 2009-10, Vol.4 (5), p.587-594

2009

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Estrogen Receptors α and β Have Similar Activities in Multiple Endothelial Cell Pathways

Endocrinology (Philadelphia), 2002-10, Vol.143 (10), p.3785-3795

2002

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Improved methods for extracting RNA from exfoliated human colonocytes in stool and RT-PCR analysis

Digestive diseases and sciences, 2004-11, Vol.49 (11-12), p.1889-1898

2004

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Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR−/− and apoE−/− mice

LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse[S]

A synthetic farnesoid X receptor (FXR) agonist promotes cholesterol lowering in models of dyslipidemia

Loss of small heterodimer partner expression in the liver protects against dyslipidemia

The Nuclear Hormone Receptor Farnesoid X Receptor (FXR) Is Activated by Androsterone

Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells

Bile acid signaling through FXR induces intracellular adhesion molecule-1 expression in mouse liver and human hepatocytes

The Chemist's Companion Guide to Patent Law

Inhibition of the CaM-Kinases augments cell death in response to oxygen radicals and oxygen radical inducing cancer therapies in MCF-7 human breast cancer cells

Indazole-Based Liver X Receptor (LXR) Modulators with Maintained Atherosclerotic Lesion Reduction Activity but Diminished Stimulation of Hepatic Triglyceride Synthesis

Circulating Cytokine Levels in Prostate Cancer Patients Undergoing Radiation Therapy: Influence of Neoadjuvant Total Androgen Suppression

Reciprocal Antagonism Between Estrogen Receptor and NF-κB Activity In Vivo

Identification of Phenylsulfone-Substituted Quinoxaline (WYE-672) as a Tissue Selective Liver X-receptor (LXR) Agonist

Improvement of Physiochemical Properties of the Tetrahydroazepinoindole Series of Farnesoid X Receptor (FXR) Agonists: Beneficial Modulation of Lipids in Primates

Response of T Lymphocyte Populations in Prostate Cancer Patients Undergoing Radiotherapy: Influence of Neoajuvant Total Androgen Suppression

Estrogen Receptor α Regulates Expression of the Orphan Receptor Small Heterodimer Partner

Pyrrole[2,3- d]azepino compounds as agonists of the farnesoid X receptor (FXR)

Loss of small heterodimer partner expression in the liver protects against dyslipidemias

Estrogen Receptor α Inhibits IL-1β Induction of Gene Expression in the Mouse Liver

Global Transcription Profiling of Estrogen Activity: Estrogen Receptor α Regulates Gene Expression in the Kidney

346 Increased Hepatic Bile Acid (BA) Synthesis Prevents Cholesterol Gallstones in Small Heterodimer Partner (SHP) Knockout Mice

Inhibition of complement activity by humanized anti-C5 antibody and single-chain Fv

Farnesoid X receptor as a therapeutic target for dyslipidemia

Estrogen Receptors α and β Have Similar Activities in Multiple Endothelial Cell Pathways

Improved methods for extracting RNA from exfoliated human colonocytes in stool and RT-PCR analysis

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