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Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond

Advanced drug delivery reviews, 2019-02, Vol.141, p.92-103

2019

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role of IL-21 in regulating B-cell function in health and disease

Immunological reviews, 2008-06, Vol.223 (1), p.60-86

2008

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Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models

The Journal of clinical investigation, 2018-05, Vol.128 (5), p.1873-1887

2018

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B-cell targeted therapeutics in clinical development

Arthritis research & therapy, 2013-01, Vol.15 Suppl 1 (S1), p.S4-S4, Article S4

2013

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Identification and characterization of circulating human transitional B cells

Blood, 2005-06, Vol.105 (11), p.4390-4398

2005

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Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation

The Journal of clinical investigation, 2018-07, Vol.128 (7), p.2966-2978

2018

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Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (21), p.9801-9806

2010

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Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease

European journal of clinical investigation, 2013-05, Vol.43 (5), p.501-509

2013

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Regulation of B Cell Differentiation and Plasma Cell Generation by IL-21, a Novel Inducer of Blimp-1 and Bcl-6

The Journal of immunology (1950), 2004-11, Vol.173 (9), p.5361-5371

2004

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IL-21 and BAFF/BLyS Synergize in Stimulating Plasma Cell Differentiation from a Unique Population of Human Splenic Memory B Cells

Journal of Immunology, 2007-03, Vol.178 (5), p.2872-2882

2007

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Development of an antibody that neutralizes soluble IgE and eliminates IgE expressing B cells

Cellular & molecular immunology, 2016-05, Vol.13 (3), p.391-400

2016

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Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation

The Journal of immunology (1950), 2011-10, Vol.187 (7), p.3603-3612

2011

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Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy

PloS one, 2019-01, Vol.14 (1), p.e0211236-e0211236

2019

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Pathogenic mechanisms of IgE-mediated inflammation in self-destructive autoimmune responses

Autoimmunity (Chur, Switzerland), 2017-02, Vol.50 (1), p.25-36

2017

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Transcriptome and IgH Repertoire Analyses Show That CD11chi B Cells Are a Distinct Population With Similarity to B Cells Arising in Autoimmunity and Infection

Frontiers in immunology, 2021-03, Vol.12, p.649458-649458

2021

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The Interplay of IL-21 and BAFF in the Formation and Maintenance of Human B Cell Memory

Frontiers in immunology, 2012-01, Vol.3, p.2-2

2012

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IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE

Nature communications, 2018-05, Vol.9 (1), p.1-14, Article 1758

2018

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Human Herpes Virus 8 - Unrelated Primary Effusion Lymphoma-Like Lymphoma: Classification, Diagnosis, and Management

Chest, 2014-10, Vol.146 (4), p.478A-478A

2014

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Role of CD11c+ T-bet+ B cells in human health and disease

Cellular immunology, 2017-11, Vol.321, p.40-45

2017

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A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity

Science translational medicine, 2019-04, Vol.11 (489)

2019

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Lifelong memory responses perpetuate humoral T H 2 immunity and anaphylaxis in food allergy

Journal of allergy and clinical immunology, 2017-12, Vol.140 (6), p.1604-1615.e5

2017

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Essential Role of IL-21 in B Cell Activation, Expansion, and Plasma Cell Generation during CD4+ T Cell-B Cell Collaboration

The Journal of immunology (1950), 2007-11, Vol.179 (9), p.5886-5896

2007

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Lifelong memory responses perpetuate humoral TH2 immunity and anaphylaxis in food allergy

Journal of allergy and clinical immunology, 2017-12, Vol.140 (6), p.1604-1615.e5

2017

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IL-21 Induces Differentiation of Human Naive and Memory B Cells into Antibody-Secreting Plasma Cells

Journal of Immunology, 2005-12, Vol.175 (12), p.7867-7879

2005

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Blockade of critical immune regulators results in different roads to pathogenesis in Primary Sjögren’s syndrome

The Journal of immunology (1950), 2017-05, Vol.198 (1_Supplement), p.207-207.12

2017

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Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond

role of IL-21 in regulating B-cell function in health and disease

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models

B-cell targeted therapeutics in clinical development

Identification and characterization of circulating human transitional B cells

Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation

Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome

Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease

Regulation of B Cell Differentiation and Plasma Cell Generation by IL-21, a Novel Inducer of Blimp-1 and Bcl-6

IL-21 and BAFF/BLyS Synergize in Stimulating Plasma Cell Differentiation from a Unique Population of Human Splenic Memory B Cells

Development of an antibody that neutralizes soluble IgE and eliminates IgE expressing B cells

Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation

Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy

Pathogenic mechanisms of IgE-mediated inflammation in self-destructive autoimmune responses

Transcriptome and IgH Repertoire Analyses Show That CD11chi B Cells Are a Distinct Population With Similarity to B Cells Arising in Autoimmunity and Infection

The Interplay of IL-21 and BAFF in the Formation and Maintenance of Human B Cell Memory

IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE

Human Herpes Virus 8 - Unrelated Primary Effusion Lymphoma-Like Lymphoma: Classification, Diagnosis, and Management

Role of CD11c+ T-bet+ B cells in human health and disease

A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity

Lifelong memory responses perpetuate humoral T H 2 immunity and anaphylaxis in food allergy

Essential Role of IL-21 in B Cell Activation, Expansion, and Plasma Cell Generation during CD4+ T Cell-B Cell Collaboration

Lifelong memory responses perpetuate humoral TH2 immunity and anaphylaxis in food allergy

IL-21 Induces Differentiation of Human Naive and Memory B Cells into Antibody-Secreting Plasma Cells

Blockade of critical immune regulators results in different roads to pathogenesis in Primary Sjögren’s syndrome

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