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Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition

Nature reviews. Cancer, 2007-05, Vol.7 (5), p.332-344

2007

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A multi‐analyte cell‐free DNA–based blood test for early detection of hepatocellular carcinoma

Hepatology communications, 2022-07, Vol.6 (7), p.1753-1763

2022

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Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia

Nature immunology, 2014-03, Vol.15 (3), p.294

2014

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Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2 V617F

PloS one, 2006-12, Vol.1 (1), p.e18-e18

2006

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Differential regulation of myeloid leukemias by the bone marrow microenvironment

Nature medicine, 2013-11, Vol.19 (11), p.1513-1517

2013

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Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia

Leukemia, 2020-08, Vol.34 (8), p.2087-2101

2020

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Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells

Nature medicine, 2006-10, Vol.12 (10), p.1175-1180

2006

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Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells

The Journal of clinical investigation, 2009-05, Vol.119 (5), p.1109-1123

2009

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Cardiotoxicity of the cancer therapeutic agent imatinib mesylate

Nature medicine, 2006-08, Vol.12 (8), p.908-916

2006

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The impact of Rhodiola rosea on biomarkers of diabetes, inflammation, and microbiota in a leptin receptor-knockout mouse model

Scientific reports, 2022-06, Vol.12 (1), p.10581-10581, Article 10581

2022

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Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia

Genes & development, 2016-09, Vol.30 (17), p.1971-1990

2016

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Alternative approaches to eradicating the malignant clone in chronic myeloid leukemia: tyrosine-kinase inhibitor combinations and beyond

Hematology, 2013, Vol.2013 (1), p.189-200

2013

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Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies

Hematological oncology, 2022-10, Vol.40 (4), p.491-504

2022

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Illuminating novel biological aspects and potential new therapeutic approaches for chronic myeloproliferative malignancies

Hematological oncology, 2020-12, Vol.38 (5), p.654-664

2020

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Peroxiredoxin1 Prevents Excessive Endothelial Activation and Early Atherosclerosis

Circulation research, 2008-09, Vol.103 (6), p.598-605

2008

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BCL6: A Novel Target for Therapy of Ph + B Cell Acute Lymphoblastic Leukemia

Cancer cell, 2011-07, Vol.20 (1), p.3-5

Van Etten, Richard A

2011

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Oncogenic signaling: new insights and controversies from chronic myeloid leukemia

The Journal of experimental medicine, 2007-03, Vol.204 (3), p.461-465

Van Etten, Richard A

2007

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Essential role for Stat5a/b in myeloproliferative neoplasms induced by BCR-ABL1 and JAK2(V617F) in mice

Blood, 2012-04, Vol.119 (15), p.3550

2012

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Autoinhibition of Bcr-Abl through Its SH3 Domain

Molecular cell, 2003-07, Vol.12 (1), p.27-37

2003

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Clinical Resistance to the Kinase Inhibitor STI-571 in Chronic Myeloid Leukemia by Mutation of Tyr-253 in the Abl Kinase Domain P-Loop

Proceedings of the National Academy of Sciences - PNAS, 2002-08, Vol.99 (16), p.10700-10705

2002

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IKK-dependent activation of NF-κB contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1

Blood, 2014-04, Vol.123 (15), p.2401-2411

2014

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Focus on myeloproliferative diseases and myelodysplastic syndromes

Cancer cell, 2004-12, Vol.6 (6), p.547-552

2004

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Retargeting NK-92 cells by means of CD19- and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity

Oncoimmunology, 2013-10, Vol.2 (10), p.e26527-e26527

2013

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Selectins and their ligands are required for homing and engraftment of BCR-ABL1+ leukemic stem cells in the bone marrow niche

Blood, 2014-02, Vol.123 (9), p.1361-1371

2014

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Children and Adolescents with Chronic Myeloproliferative Neoplasms: Still an Unmet Biological and Clinical Need?

HemaSphere, 2019-10, Vol.3 (5), p.1-3

2019

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Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition

A multi‐analyte cell‐free DNA–based blood test for early detection of hepatocellular carcinoma

Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia

Molecular pathogenesis and therapy of polycythemia induced in mice by JAK2 V617F

Differential regulation of myeloid leukemias by the bone marrow microenvironment

Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia

Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells

Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells

Cardiotoxicity of the cancer therapeutic agent imatinib mesylate

The impact of Rhodiola rosea on biomarkers of diabetes, inflammation, and microbiota in a leptin receptor-knockout mouse model

Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia

Alternative approaches to eradicating the malignant clone in chronic myeloid leukemia: tyrosine-kinase inhibitor combinations and beyond

Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies

Illuminating novel biological aspects and potential new therapeutic approaches for chronic myeloproliferative malignancies

Peroxiredoxin1 Prevents Excessive Endothelial Activation and Early Atherosclerosis

BCL6: A Novel Target for Therapy of Ph + B Cell Acute Lymphoblastic Leukemia

Oncogenic signaling: new insights and controversies from chronic myeloid leukemia

Essential role for Stat5a/b in myeloproliferative neoplasms induced by BCR-ABL1 and JAK2(V617F) in mice

Autoinhibition of Bcr-Abl through Its SH3 Domain

Clinical Resistance to the Kinase Inhibitor STI-571 in Chronic Myeloid Leukemia by Mutation of Tyr-253 in the Abl Kinase Domain P-Loop

IKK-dependent activation of NF-κB contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1

Focus on myeloproliferative diseases and myelodysplastic syndromes

Retargeting NK-92 cells by means of CD19- and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity

Selectins and their ligands are required for homing and engraftment of BCR-ABL1+ leukemic stem cells in the bone marrow niche

Children and Adolescents with Chronic Myeloproliferative Neoplasms: Still an Unmet Biological and Clinical Need?

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