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Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate

Drug metabolism and disposition, 2019-09, Vol.47 (9), p.974-982

2019

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Surface hydrophobics mediate functional dimerization of CYP121A1 of Mycobacterium tuberculosis

Scientific reports, 2021-01, Vol.11 (1), p.394-14, Article 394

2021

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Evidence of Allosteric Coupling between Substrate Binding and Adx Recognition in the Vitamin D Carbon-24 Hydroxylase CYP24A1

Biochemistry (Easton), 2020-04, Vol.59 (15), p.1537-1548

2020

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Structural basis of bidirectional allostery across the heme in a cytochrome P450 enzyme

The Journal of biological chemistry, 2023-08, Vol.299 (8), p.104977-104977, Article 104977

2023

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The cytochrome P450 24A1 interaction with adrenodoxin relies on multiple recognition sites that vary among species

The Journal of biological chemistry, 2018-03, Vol.293 (11), p.4167-4179

Estrada, D. Fernando

2018

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Interactions of human mitochondrial Ferredoxin 1 (Adrenodoxin) by NMR; modulation by cytochrome P450 substrate and by truncation of the C-terminal tail

Journal of inorganic biochemistry, 2023-12, Vol.249, p.112370-112370, Article 112370

2023

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Characterization of a Cleavable Fusion of Human CYP24A1 with Adrenodoxin Reveals the Variable Role of Hydrophobics in Redox Partner Binding

Biochemistry (Easton), 2022-01, Vol.61 (2), p.57-66

2022

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The Hantavirus Glycoprotein G1 Tail Contains Dual CCHC-type Classical Zinc Fingers

The Journal of biological chemistry, 2009-03, Vol.284 (13), p.8654-8660

2009

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Cytochrome P450 17A1 Interactions with the FMN Domain of Its Reductase as Characterized by NMR

The Journal of biological chemistry, 2016-02, Vol.291 (8), p.3990-4003

2016

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Substrate-modulated Cytochrome P450 17A1 and Cytochrome b5 Interactions Revealed by NMR

The Journal of biological chemistry, 2013-06, Vol.288 (23), p.17008-17018

2013

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Asparagine-85 Stabilizes a Structural Active Site Water Network in CYP121A1 of Mycobacterium tuberculosis

Biochemistry (Easton), 2024-03, Vol.63 (5), p.711-722

2024

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19F-NMR reveals substrate specificity of CYP121A1 in Mycobacterium tuberculosis

The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101287-101287, Article 101287

2021

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Tracking protein–protein interactions by NMR: conformational selection in human steroidogenic cytochrome P450 CYP17A1 induced by cytochrome b5

Physical chemistry chemical physics : PCCP, 2024-06, Vol.26 (24), p.16980-16988

2024

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Crystal Structures of Drug-Metabolizing CYPs

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2342, p.171

2021

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Tracking protein-protein interactions by NMR: conformational selection in human steroidogenic cytochrome P450 CYP17A1 induced by cytochrome b 5

Physical chemistry chemical physics : PCCP, 2024-06, Vol.26 (24), p.16980-16988

2024

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Human cytochrome P450 17A1 conformational selection: modulation by ligand and cytochrome b5

The Journal of biological chemistry, 2014-05, Vol.289 (20), p.14310-14320

2014

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Structural insights into the function of steroidogenic cytochrome P450 17A1

Molecular and cellular endocrinology, 2017-02, Vol.441, p.68-75

2017

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Synthesis, biological evaluation and computational studies of pyrazole derivatives as Mycobacterium tuberculosis CYP121A1 inhibitors

RSC medicinal chemistry, 2022-11, Vol.13 (11), p.1350-1360

2022

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NMR Structure of the N-terminal Coiled Coil Domain of the Andes Hantavirus Nucleocapsid Protein

The Journal of biological chemistry, 2008-10, Vol.283 (42), p.28297-28304

2008

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Structural Characterization of the Crimean-Congo Hemorrhagic Fever Virus Gn Tail Provides Insight into Virus Assembly

The Journal of biological chemistry, 2011-06, Vol.286 (24), p.21678-21686

2011

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The Structure of the Hantavirus Zinc Finger Domain is Conserved and Represents the Only Natively Folded Region of the Gn Cytoplasmic Tail

Frontiers in microbiology, 2011-01, Vol.2, p.251-251

2011

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The Role of Protein-Protein and Protein-Membrane Interactions on P450 Function

Drug metabolism and disposition, 2016-04, Vol.44 (4), p.576-590

2016

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Active Site Aromatic Residues Play a Dual Role in the Substrate Interaction and Protein Structure in Functional Dimers of CYP121A1 of Mycobacterium tuberculosis

ACS infectious diseases, 2023-04, Vol.9 (4), p.827-839

2023

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Abstract 1175 A Substrate Tug of War: How Cholesterol and Vitamin D3 Differentially Regulate CYP11A1 Structure and Redox Partner Interaction

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.106839, Article 106839

2024

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Abstract 1169 Novel pH sensing ability in cytochrome P450 enzyme CYP107 from Sebekia benihana

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.106837, Article 106837

2024

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Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate

Surface hydrophobics mediate functional dimerization of CYP121A1 of Mycobacterium tuberculosis

Evidence of Allosteric Coupling between Substrate Binding and Adx Recognition in the Vitamin D Carbon-24 Hydroxylase CYP24A1

Structural basis of bidirectional allostery across the heme in a cytochrome P450 enzyme

The cytochrome P450 24A1 interaction with adrenodoxin relies on multiple recognition sites that vary among species

Interactions of human mitochondrial Ferredoxin 1 (Adrenodoxin) by NMR; modulation by cytochrome P450 substrate and by truncation of the C-terminal tail

Characterization of a Cleavable Fusion of Human CYP24A1 with Adrenodoxin Reveals the Variable Role of Hydrophobics in Redox Partner Binding

The Hantavirus Glycoprotein G1 Tail Contains Dual CCHC-type Classical Zinc Fingers

Cytochrome P450 17A1 Interactions with the FMN Domain of Its Reductase as Characterized by NMR

Substrate-modulated Cytochrome P450 17A1 and Cytochrome b5 Interactions Revealed by NMR

Asparagine-85 Stabilizes a Structural Active Site Water Network in CYP121A1 of Mycobacterium tuberculosis

19F-NMR reveals substrate specificity of CYP121A1 in Mycobacterium tuberculosis

Tracking protein–protein interactions by NMR: conformational selection in human steroidogenic cytochrome P450 CYP17A1 induced by cytochrome b5

Crystal Structures of Drug-Metabolizing CYPs

Tracking protein-protein interactions by NMR: conformational selection in human steroidogenic cytochrome P450 CYP17A1 induced by cytochrome b 5

Human cytochrome P450 17A1 conformational selection: modulation by ligand and cytochrome b5

Structural insights into the function of steroidogenic cytochrome P450 17A1

Synthesis, biological evaluation and computational studies of pyrazole derivatives as Mycobacterium tuberculosis CYP121A1 inhibitors

NMR Structure of the N-terminal Coiled Coil Domain of the Andes Hantavirus Nucleocapsid Protein

Structural Characterization of the Crimean-Congo Hemorrhagic Fever Virus Gn Tail Provides Insight into Virus Assembly

The Structure of the Hantavirus Zinc Finger Domain is Conserved and Represents the Only Natively Folded Region of the Gn Cytoplasmic Tail

The Role of Protein-Protein and Protein-Membrane Interactions on P450 Function

Active Site Aromatic Residues Play a Dual Role in the Substrate Interaction and Protein Structure in Functional Dimers of CYP121A1 of Mycobacterium tuberculosis

Abstract 1175 A Substrate Tug of War: How Cholesterol and Vitamin D3 Differentially Regulate CYP11A1 Structure and Redox Partner Interaction

Abstract 1169 Novel pH sensing ability in cytochrome P450 enzyme CYP107 from Sebekia benihana

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