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SAMHD1: At the Crossroads of Cell Proliferation, Immune Responses, and Virus Restriction

Trends in microbiology (Regular ed.), 2015-11, Vol.23 (11), p.680-692

2015

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Current status and challenges of antiretroviral research and therapy

Antiviral research, 2010, Vol.85 (1), p.25-33

2010

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HIV entry inhibitors

The Lancet (British edition), 2007-07, Vol.370 (9581), p.81-88

2007

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Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells

The Journal of immunology (1950), 2014-08, Vol.193 (4), p.1988-1997

2014

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Inhibition of HIV-1 replication by RNA interference of p53 expression

Journal of leukocyte biology, 2006-09, Vol.80 (3), p.659-667

2006

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Applications of 3-aminolactams: design, synthesis, and biological evaluation of a library of potential dimerisation inhibitors of HIV1-protease

Organic & biomolecular chemistry, 2012-06, Vol.10 (22), p.4348-4354

2012

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CD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir

Nature communications, 2018-07, Vol.9 (1), p.2739-10, Article 2739

2018

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Antiretroviral Agents Effectively Block HIV Replication after Cell-to-Cell Transfer

Journal of Virology, 2012-08, Vol.86 (16), p.8773-8780

2012

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Towards novel S-DABOC inhibitors: Synthesis, biological investigation, and molecular modeling studies

Bioorganic & medicinal chemistry, 2008-11, Vol.18 (21), p.5777-5780

2008

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RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

Scientific reports, 2017-10, Vol.7 (1), p.13339-14, Article 13339

2017

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Indolylarylsulfones Carrying a Heterocyclic Tail as Very Potent and Broad Spectrum HIV‑1 Non-nucleoside Reverse Transcriptase Inhibitors

Journal of medicinal chemistry, 2014-12, Vol.57 (23), p.9945-9957

2014

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Secretion of interferon-γ by human macrophages demonstrated at the single-cell level after costimulation with interleukin (IL)-12 plus IL-18

Immunology, 2009-03, Vol.126 (3), p.386-393

2009

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Zinc Finger Endonuclease Targeting PSIP1 Inhibits HIV-1 Integration

Antimicrobial agents and chemotherapy, 2014-08, Vol.58 (8), p.4318-4327

2014

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Palbociclib, a selective inhibitor of cyclin-dependent kinase4/6, blocks HIV-1 reverse transcription through the control of sterile α motif and HD domain-containing protein-1 (SAMHD1) activity

AIDS (London), 2014-09, Vol.28 (15), p.2213-2222

2014

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The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells

PLoS pathogens, 2016-08, Vol.12 (8), p.e1005829-e1005829

2016

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Chiral Indolylarylsulfone Non-Nucleoside Reverse Transcriptase Inhibitors as New Potent and Broad Spectrum Anti-HIV‑1 Agents

Journal of medicinal chemistry, 2017-08, Vol.60 (15), p.6528-6547

2017

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Effect of α‑Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3H)‑ones

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.604-621

2019

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New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains

European journal of medicinal chemistry, 2020-12, Vol.208, p.112696-112696, Article 112696

2020

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New Nitrogen Containing Substituents at the Indole-2-carboxamide Yield High Potent and Broad Spectrum Indolylarylsulfone HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Journal of medicinal chemistry, 2012-07, Vol.55 (14), p.6634-6638

2012

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p21 regulates the HIV-1 restriction factor SAMHD1

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (14), p.E1322-E1324

2014

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ADAR1 affects HCV infection by modulating innate immune response

Antiviral research, 2018-08, Vol.156, p.116-127

2018

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Evaluation of the Innate Immune Modulator Acitretin as a Strategy To Clear the HIV Reservoir

Antimicrobial agents and chemotherapy, 2017-11, Vol.61 (11)

2017

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ADS-J1 Inhibits HIV-1 Entry by Interacting with gp120 and Does Not Block Fusion-Active gp41 Core Formation

Antimicrobial Agents and Chemotherapy, 2010-10, Vol.54 (10), p.4487-4492

2010

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Use of N-Methylpiperazine for the Preparation of Piperazine-Based Unsymmetrical Bis-Ureas as Anti-HIV Agents

ChemMedChem, 2008-07, Vol.3 (7), p.1034-1037

2008

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Inhibition of herpes simplex virus type 1 by the CDK6 inhibitor PD-0332991 (palbociclib) through the control of SAMHD1

Journal of antimicrobial chemotherapy, 2016-02, Vol.71 (2), p.387-394

2016

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SAMHD1: At the Crossroads of Cell Proliferation, Immune Responses, and Virus Restriction

Current status and challenges of antiretroviral research and therapy

HIV entry inhibitors

Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells

Inhibition of HIV-1 replication by RNA interference of p53 expression

Applications of 3-aminolactams: design, synthesis, and biological evaluation of a library of potential dimerisation inhibitors of HIV1-protease

CD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir

Antiretroviral Agents Effectively Block HIV Replication after Cell-to-Cell Transfer

Towards novel S-DABOC inhibitors: Synthesis, biological investigation, and molecular modeling studies

RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

Indolylarylsulfones Carrying a Heterocyclic Tail as Very Potent and Broad Spectrum HIV‑1 Non-nucleoside Reverse Transcriptase Inhibitors

Secretion of interferon-γ by human macrophages demonstrated at the single-cell level after costimulation with interleukin (IL)-12 plus IL-18

Zinc Finger Endonuclease Targeting PSIP1 Inhibits HIV-1 Integration

Palbociclib, a selective inhibitor of cyclin-dependent kinase4/6, blocks HIV-1 reverse transcription through the control of sterile α motif and HD domain-containing protein-1 (SAMHD1) activity

The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells

Chiral Indolylarylsulfone Non-Nucleoside Reverse Transcriptase Inhibitors as New Potent and Broad Spectrum Anti-HIV‑1 Agents

Effect of α‑Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3H)‑ones

New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains

New Nitrogen Containing Substituents at the Indole-2-carboxamide Yield High Potent and Broad Spectrum Indolylarylsulfone HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

p21 regulates the HIV-1 restriction factor SAMHD1

ADAR1 affects HCV infection by modulating innate immune response

Evaluation of the Innate Immune Modulator Acitretin as a Strategy To Clear the HIV Reservoir

ADS-J1 Inhibits HIV-1 Entry by Interacting with gp120 and Does Not Block Fusion-Active gp41 Core Formation

Use of N-Methylpiperazine for the Preparation of Piperazine-Based Unsymmetrical Bis-Ureas as Anti-HIV Agents

Inhibition of herpes simplex virus type 1 by the CDK6 inhibitor PD-0332991 (palbociclib) through the control of SAMHD1

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