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Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Nonclinical Models

Clinical cancer research, 2017-11, Vol.23 (21), p.6661-6672

2017

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Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13), p.3672-3687

2018

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Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/p38 signaling

Epigenetics & chromatin, 2021-01, Vol.14 (1), p.7-7, Article 7

2021

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NF1 deficiency drives metabolic reprogramming in ER+ breast cancer

Molecular metabolism (Germany), 2024-02, Vol.80, p.101876-101876, Article 101876

2024

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Nf1 deficiency modulates the stromal environment in the pretumorigenic rat mammary gland

Frontiers in cell and developmental biology, 2024, Vol.12, p.1375441-1375441

2024

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Kinome Profiling of NF1-Related MPNSTs in Response to Kinase Inhibition and Doxorubicin Reveals Therapeutic Vulnerabilities

Genes, 2020-03, Vol.11 (3), p.331

2020

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Ex Vivo Patient-Derived Explant Model for Neurofibromatosis Type 1–Related Cutaneous Neurofibromas

Journal of investigative dermatology, 2024-02, Vol.144 (9), p.2052-2065.e8

2024

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p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs

Oncogene, 2024-05, Vol.43 (19), p.1411-1430

2024

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Cabozantinib (XL184) Inhibits Growth and Invasion of Preclinical TNBC Models

Clinical cancer research, 2016-02, Vol.22 (4), p.923-934

2016

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Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers

Oncotarget, 2016-10, Vol.7 (43), p.69903-69915

2016

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NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer

NPJ breast cancer, 2018-08, Vol.4 (1), p.29-14, Article 29

2018

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Dissecting the Rat Mammary Gland: Isolation, Characterization, and Culture of Purified Mammary Epithelial Cells and Fibroblasts

Bio-protocol, 2020-11, Vol.10 (22), p.e3818-e3818

2020

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In vivo Efficacy Studies in Cell Line and Patient-derived Xenograft Mouse Models

Bio-protocol, 2017-01, Vol.7 (1), p.e2100-e2100

2017

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Abstract B19: MET and IL6 signaling in triple-negative breast cancer

Molecular cancer research, 2016-02, Vol.14 (2_Supplement), p.B19-B19

2016

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Abstract B14: Targeting the intratumoral heterogeneity of receptor tyrosine kinases in breast cancer

Molecular cancer research, 2016-02, Vol.14 (2_Supplement), p.B14-B14

2016

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Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (2), p.570-575

2012

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Overexpression of HGF Promotes HBV-Induced Hepatocellular Carcinoma Progression and Is an Effective Indicator for Met-Targeting Therapy

Genes & cancer, 2013-07, Vol.4 (7-8), p.247-260

2013

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Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Nonclinical Models

Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors

Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/p38 signaling

NF1 deficiency drives metabolic reprogramming in ER+ breast cancer

Nf1 deficiency modulates the stromal environment in the pretumorigenic rat mammary gland

Kinome Profiling of NF1-Related MPNSTs in Response to Kinase Inhibition and Doxorubicin Reveals Therapeutic Vulnerabilities

Ex Vivo Patient-Derived Explant Model for Neurofibromatosis Type 1–Related Cutaneous Neurofibromas

p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs

Cabozantinib (XL184) Inhibits Growth and Invasion of Preclinical TNBC Models

Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers

NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer

Dissecting the Rat Mammary Gland: Isolation, Characterization, and Culture of Purified Mammary Epithelial Cells and Fibroblasts

In vivo Efficacy Studies in Cell Line and Patient-derived Xenograft Mouse Models

Abstract B19: MET and IL6 signaling in triple-negative breast cancer

Abstract B14: Targeting the intratumoral heterogeneity of receptor tyrosine kinases in breast cancer

Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

Overexpression of HGF Promotes HBV-Induced Hepatocellular Carcinoma Progression and Is an Effective Indicator for Met-Targeting Therapy

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