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High affinity nanobodies block SARS-CoV-2 spike receptor binding domain interaction with human angiotensin converting enzyme

Scientific reports, 2020-12, Vol.10 (1), p.22370-13, Article 22370

2020

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Selection of single domain anti-transferrin receptor antibodies for blood-brain barrier transcytosis using a neurotensin based assay and histological assessment of target engagement in a mouse model of Alzheimer’s related amyloid-beta pathology

PloS one, 2022-10, Vol.17 (10), p.e0276107-e0276107

2022

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Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls

Annals of neurology, 2013-01, Vol.73 (1), p.104-119

2013

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Soluble Amyloid-beta Aggregates from Human Alzheimer’s Disease Brains

Scientific reports, 2016-12, Vol.6 (1), p.38187-38187, Article 38187

2016

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Real-time environmental surveillance of SARS-CoV-2 aerosols

Nature communications, 2023-07, Vol.14 (1), p.3692-3692, Article 3692

2023

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Unbiased high-content screening reveals Aβ- and tau-independent synaptotoxic activities in human brain homogenates from Alzheimer's patients and high-pathology controls

PloS one, 2021-11, Vol.16 (11), p.e0259335

2021

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Non-canonical soluble amyloid-beta aggregates and plaque buffering: controversies and future directions for target discovery in Alzheimer's disease

Alzheimer's research & therapy, 2017-08, Vol.9 (1), p.62-13, Article 62

2017

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Distinct temporal and anatomical distributions of amyloid-β and tau abnormalities following controlled cortical impact in transgenic mice

PloS one, 2011-09, Vol.6 (9), p.e25475-e25475

2011

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Soluble amyloid-beta buffering by plaques in Alzheimer disease dementia versus high-pathology controls

PloS one, 2018-07, Vol.13 (7), p.e0200251

2018

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Pharmacokinetics of Single Domain Antibodies and Conjugated Nanoparticles Using a Hybrid near Infrared Method

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8695

2021

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Enhanced in vivo blood brain barrier transcytosis of macromolecular cargo using an engineered pH-sensitive mouse transferrin receptor binding nanobody

Fluids and barriers of the CNS, 2023-08, Vol.20 (1), p.1-64, Article 64

2023

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Nebulized delivery of a broadly neutralizing SARS-CoV-2 RBD-specific nanobody prevents clinical, virological, and pathological disease in a Syrian hamster model of COVID-19

mAbs, 2022, Vol.14 (1), p.2047144-2047144

2022

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Sensitive detection of extremely small iron oxide nanoparticles in living mice using MP2RAGE with advanced image co-registration

Scientific reports, 2021-01, Vol.11 (1), p.106-106, Article 106

2021

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Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis

Neuron (Cambridge, Mass.), 2017-12, Vol.96 (5), p.1013-1023.e4

2017

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Diversity of Amyloid-beta Proteoforms in the Alzheimer’s Disease Brain

Scientific reports, 2017-08, Vol.7 (1), p.9520-9, Article 9520

2017

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Traumatic brain injury reduces soluble extracellular amyloid-β in mice: A methodologically novel combined microdialysis-controlled cortical impact study

Neurobiology of disease, 2010-12, Vol.40 (3), p.555-564

2010

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Selection of single domain anti-transferrin receptor antibodies for blood-brain barrier transcytosis using a neurotensin based assay and histological assessment of target engagement in a mouse model of Alzheimer's related amyloid-beta pathology

PloS one, 2022-10, Vol.17 (10), p.e0276107

2022

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Single-Domain Antibodies for the Detection of SARS-CoV‑2 Nucleocapsid Protein

Analytical chemistry (Washington), 2021-05, Vol.93 (19), p.7283-7291

2021

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Tau elevations in the brain extracellular space correlate with reduced amyloid-β levels and predict adverse clinical outcomes after severe traumatic brain injury

Brain (London, England : 1878), 2012-04, Vol.135 (Pt 4), p.1268-1280

2012

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Molecular and Biochemical Characterization of a Cytokinin Oxidase from Maize

Plant physiology (Bethesda), 2001-01, Vol.125 (1), p.378-386

2001

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Repetitive Concussive and Subconcussive Injury in a Human Tau Mouse Model Results in Chronic Cognitive Dysfunction and Disruption of White Matter Tracts, But Not Tau Pathology

Journal of neurotrauma, 2019-03, Vol.36 (5), p.735-755

2019

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Unbiased high-content screening reveals Aβ- and tau-independent synaptotoxic activities in human brain homogenates from Alzheimer’s patients and high-pathology controls

PloS one, 2021-01, Vol.16 (11)

2021

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Live Neuron High-Content Screening Reveals Synaptotoxic Activity in Alzheimer Mouse Model Homogenates

Scientific reports, 2020-02, Vol.10 (1), p.3412, Article 3412

2020

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Amyloid-β Dynamics Correlate with Neurological Status in the Injured Human Brain

Science (American Association for the Advancement of Science), 2008-08, Vol.321 (5893), p.1221-1224

2008

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High affinity nanobodies block SARS-CoV-2 spike receptor binding domain interaction with human angiotensin converting enzyme

Selection of single domain anti-transferrin receptor antibodies for blood-brain barrier transcytosis using a neurotensin based assay and histological assessment of target engagement in a mouse model of Alzheimer’s related amyloid-beta pathology

Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls

Soluble Amyloid-beta Aggregates from Human Alzheimer’s Disease Brains

Real-time environmental surveillance of SARS-CoV-2 aerosols

Unbiased high-content screening reveals Aβ- and tau-independent synaptotoxic activities in human brain homogenates from Alzheimer's patients and high-pathology controls

Non-canonical soluble amyloid-beta aggregates and plaque buffering: controversies and future directions for target discovery in Alzheimer's disease

Distinct temporal and anatomical distributions of amyloid-β and tau abnormalities following controlled cortical impact in transgenic mice

Soluble amyloid-beta buffering by plaques in Alzheimer disease dementia versus high-pathology controls

Pharmacokinetics of Single Domain Antibodies and Conjugated Nanoparticles Using a Hybrid near Infrared Method

Enhanced in vivo blood brain barrier transcytosis of macromolecular cargo using an engineered pH-sensitive mouse transferrin receptor binding nanobody

Nebulized delivery of a broadly neutralizing SARS-CoV-2 RBD-specific nanobody prevents clinical, virological, and pathological disease in a Syrian hamster model of COVID-19

Sensitive detection of extremely small iron oxide nanoparticles in living mice using MP2RAGE with advanced image co-registration

Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis

Diversity of Amyloid-beta Proteoforms in the Alzheimer’s Disease Brain

Traumatic brain injury reduces soluble extracellular amyloid-β in mice: A methodologically novel combined microdialysis-controlled cortical impact study

Selection of single domain anti-transferrin receptor antibodies for blood-brain barrier transcytosis using a neurotensin based assay and histological assessment of target engagement in a mouse model of Alzheimer's related amyloid-beta pathology

Single-Domain Antibodies for the Detection of SARS-CoV‑2 Nucleocapsid Protein

Tau elevations in the brain extracellular space correlate with reduced amyloid-β levels and predict adverse clinical outcomes after severe traumatic brain injury

Molecular and Biochemical Characterization of a Cytokinin Oxidase from Maize

Repetitive Concussive and Subconcussive Injury in a Human Tau Mouse Model Results in Chronic Cognitive Dysfunction and Disruption of White Matter Tracts, But Not Tau Pathology

Unbiased high-content screening reveals Aβ- and tau-independent synaptotoxic activities in human brain homogenates from Alzheimer’s patients and high-pathology controls

Live Neuron High-Content Screening Reveals Synaptotoxic Activity in Alzheimer Mouse Model Homogenates

Amyloid-β Dynamics Correlate with Neurological Status in the Injured Human Brain

Prospective natural history study of C9orf72 ALS clinical characteristics and biomarkers

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