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Extracellular histones increase plasma thrombin generation by impairing thrombomodulin‐dependent protein C activation

Journal of thrombosis and haemostasis, 2011-09, Vol.9 (9), p.1795-1803

2011

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Non‐hematopoietic EPCR regulates the coagulation and inflammatory responses during endotoxemia

Journal of thrombosis and haemostasis, 2007-07, Vol.5 (7), p.1394-1400

2007

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Histones induce phosphatidylserine exposure and a procoagulant phenotype in human red blood cells

Journal of thrombosis and haemostasis, 2014-10, Vol.12 (10), p.1697-1702

2014

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A monoclonal antibody against activated protein C allows rapid detection of activated protein C in plasma and reveals a calcium ion dependent epitope involved in factor Va inactivation

Journal of thrombosis and haemostasis, 2003-04, Vol.1 (4), p.662-670

2003

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Endogenous activated protein C is essential for immune-mediated cancer cell elimination from the circulation

Cancer letters, 2011-07, Vol.306 (1), p.106-110

2011

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Innate immunity and coagulation

Journal of thrombosis and haemostasis, 2011-07, Vol.9 (Suppl 1), p.182-188

2011

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Analysis of the proc gene in patients with type 2 diabetes and low levels of activated protein c

Atherosclerosis, 2012-12, Vol.225 (2), p.e5-e5

2012

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Inflammation and thrombosis

Journal of thrombosis and haemostasis, 2003-07, Vol.1 (7), p.1343-1348

Esmon, C. T.

2003

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Extracellular Histones Mediate Hepatic Ischemia-Reperfusion Injury Through A Toll-like Receptor 9-dependent Pathway

The Journal of surgical research, 2011, Vol.165 (2), p.180-180

2011

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Extracellular histones function as alarmins in hepatic ischemia/reperfusion injury through toll-like receptor 9

Journal of the American College of Surgeons, 2011, Vol.213 (3), p.S70-S70

2011

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Endothelial protein C receptor function in murine and human breast cancer development

PloS one, 2013-04, Vol.8 (4), p.e61071

2013

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Regulated endothelial protein C receptor shedding is mediated by tumor necrosis factor‐α converting enzyme/ADAM17

Journal of thrombosis and haemostasis, 2007-02, Vol.5 (2), p.395-402

2007

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Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin

Journal of thrombosis and haemostasis, 2005-07, Vol.3 (7), p.1351-1359

2005

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The Ser219–>Gly dimorphism of the endothelial protein C receptor contributes to the higher soluble protein levels observed in individuals with the A3 haplotype

Journal of thrombosis and haemostasis, 2006-01, Vol.4 (1), p.229-235

2006

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Factor VIIa binding to endothelial cell protein C receptor protects vascular barrier integrity in vivo

Journal of thrombosis and haemostasis, 2014-05, Vol.12 (5), p.690-700

2014

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The discovery of the endothelial cell protein C receptor

Journal of thrombosis and haemostasis, 2010-01, Vol.8 (1), p.2-5

ESMON, C. T.

2010

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Endogenous activated protein C signaling is critical to protection of mice from lipopolysaccaride‐induced septic shock

Journal of thrombosis and haemostasis, 2009-05, Vol.7 (5), p.851-856

2009

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Group V secretory phospholipase A2 impairs endothelial protein C receptor‐dependent protein C activation and accelerates thrombosis in vivo

Journal of thrombosis and haemostasis, 2014-11, Vol.12 (11), p.1921-1927

2014

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Endothelial cell protein C receptor‐mediated redistribution and tissue‐level accumulation of factor VIIa

Journal of thrombosis and haemostasis, 2012-11, Vol.10 (11), p.2383-2391

2012

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Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C

The Journal of biological chemistry, 1982-01, Vol.257 (2), p.859-864

1982

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Coagulation inhibitors in inflammation

Biochemical Society transactions, 2005-04, Vol.33 (Pt 2), p.401-405

Esmon, C T

2005

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The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity

The Journal of biological chemistry, 1992-06, Vol.267 (16), p.11023-11028

1992

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Surface expression and functional characterization of α-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxin

Blood, 2000-03, Vol.95 (5), p.1694-1702

2000

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Endogenous protein C has a protective role during Gram‐negative pneumosepsis (melioidosis)

Journal of thrombosis and haemostasis, 2013-02, Vol.11 (2), p.282-292

2013

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The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis

Blood, 2000-03, Vol.95 (5), p.1680-1686

2000

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Extracellular histones increase plasma thrombin generation by impairing thrombomodulin‐dependent protein C activation

Non‐hematopoietic EPCR regulates the coagulation and inflammatory responses during endotoxemia

Histones induce phosphatidylserine exposure and a procoagulant phenotype in human red blood cells

A monoclonal antibody against activated protein C allows rapid detection of activated protein C in plasma and reveals a calcium ion dependent epitope involved in factor Va inactivation

Endogenous activated protein C is essential for immune-mediated cancer cell elimination from the circulation

Innate immunity and coagulation

Analysis of the proc gene in patients with type 2 diabetes and low levels of activated protein c

Inflammation and thrombosis

Extracellular Histones Mediate Hepatic Ischemia-Reperfusion Injury Through A Toll-like Receptor 9-dependent Pathway

Extracellular histones function as alarmins in hepatic ischemia/reperfusion injury through toll-like receptor 9

Endothelial protein C receptor function in murine and human breast cancer development

Regulated endothelial protein C receptor shedding is mediated by tumor necrosis factor‐α converting enzyme/ADAM17

Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin

The Ser219–>Gly dimorphism of the endothelial protein C receptor contributes to the higher soluble protein levels observed in individuals with the A3 haplotype

Factor VIIa binding to endothelial cell protein C receptor protects vascular barrier integrity in vivo

The discovery of the endothelial cell protein C receptor

Endogenous activated protein C signaling is critical to protection of mice from lipopolysaccaride‐induced septic shock

Group V secretory phospholipase A2 impairs endothelial protein C receptor‐dependent protein C activation and accelerates thrombosis in vivo

Endothelial cell protein C receptor‐mediated redistribution and tissue‐level accumulation of factor VIIa

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C

Coagulation inhibitors in inflammation

The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity

Surface expression and functional characterization of α-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxin

Endogenous protein C has a protective role during Gram‐negative pneumosepsis (melioidosis)

The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis

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