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Evidence for a functional role of the cholecystokinin-B/gastrin receptor in the human fetal and adult pancreas

Diabetes (New York, N.Y.), 1999-10, Vol.48 (10), p.2015

1999

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Arginine 197 of the cholecystokinin-A receptor binding site interacts with the sulfate of the peptide agonist cholecystokinin

Protein science, 1999-11, Vol.8 (11), p.2347-2354

1999

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Rhodopsin crystal: new template yielding realistic models of G-protein-coupled receptors?

Trends in pharmacological sciences (Regular ed.), 2003, Vol.24 (1), p.36-40

2003

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Transgenic CCK-B/gastrin receptor mediates murine exocrine pancreatic secretion

Gastroenterology (New York, N.Y. 1943), 1998-10, Vol.115 (4), p.988-996

1998

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Probing a Model of a GPCR/Ligand Complex in an Explicit Membrane Environment: The Human Cholecystokinin-1 Receptor

Biophysical journal, 2006-02, Vol.90 (4), p.1232-1240

2006

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Identification of a Region of the N-Terminal of the Human CCKA Receptor Essential for the High Affinity Interaction with Agonist CCK

Biochemical and biophysical research communications, 1995-08, Vol.213 (3), p.845-852

1995

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A novel mechanism for JAK2 activation by a G protein-coupled receptor, the CCK2R: implication of this signaling pathway in pancreatic tumor models

The Journal of biological chemistry, 2005-03, Vol.280 (11), p.10710-10715

2005

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Modeled Structure of a G-Protein-Coupled Receptor: The Cholecystokinin-1 Receptor

Journal of medicinal chemistry, 2005-01, Vol.48 (1), p.180-191

2005

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Evidence That Interspecies Polymorphism in the Human and Rat Cholecystokinin Receptor-2 Affects Structure of the Binding Site for the Endogenous Agonist Cholecystokinin

The Journal of biological chemistry, 2005-06, Vol.280 (23), p.22198-22204

2005

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Evidences for a unique conformation of CCK2 receptor recruiting beta-arrestine2

Regulatory peptides, 2010-09, Vol.164 (1), p.27-28

2010

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Molecular Mechanism Underlying Partial and Full Agonism Mediated by the Human Cholecystokinin-1 Receptor

The Journal of biological chemistry, 2005-03, Vol.280 (11), p.10664-10674

2005

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Molecular cloning, developmental expression and pharmacological characterization of the CCKB/gastrin receptor in the calf pancreas

European journal of pharmacology, 1996-02, Vol.297 (1-2), p.165-179

1996

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Partial Agonism, Neutral Antagonism, and Inverse Agonism at the Human Wild-Type and Constitutively Active Cholecystokinin-2 Receptors

Molecular pharmacology, 2006-03, Vol.69 (3), p.680-690

2006

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Role of the Extracellular Domains of the Cholecystokinin Receptor in Agonist Binding

Molecular pharmacology, 1998-08, Vol.54 (2), p.364-371

1998

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Combination of Molecular Modeling, Site-Directed Mutagenesis, and SAR Studies To Delineate the Binding Site of Pyridopyrimidine Antagonists on the Human CCK1 Receptor

Journal of medicinal chemistry, 2005-07, Vol.48 (15), p.4842-4850

2005

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The biologically crucial C terminus of cholecystokinin and the non-peptide agonist SR-146,131 share a common binding site in the human CCK1 receptor. Evidence for a crucial role of Met-121 in the activation process

The Journal of biological chemistry, 2002-03, Vol.277 (9), p.7546

2002

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Essential interaction of Egr-1 at an islet-specific response element for basal and gastrin-dependent glucagon gene transactivation in pancreatic alpha-cells

The Journal of biological chemistry, 2005-03, Vol.280 (9), p.7976-7984

2005

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Arginine 336 and Asparagine 333 of the Human Cholecystokinin-A Receptor Binding Site Interact with the Penultimate Aspartic Acid and the C-terminal Amide of Cholecystokinin

The Journal of biological chemistry, 1999-07, Vol.274 (29), p.20457-20464

1999

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Identification of Tyrosine 189 and Asparagine 358 of the Cholecystokinin 2 Receptor in Direct Interaction with the Crucial C-Terminal Amide of Cholecystokinin by Molecular Modeling, Site-Directed Mutagenesis, and Structure/Affinity Studies

Molecular pharmacology, 2003-05, Vol.63 (5), p.973-982

2003

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Photoaffinity labeling of rat pancreatic cholecystokinin type A receptor antagonist binding sites demonstrates the presence of a truncated cholecystokinin type A receptor

Molecular pharmacology, 1994-04, Vol.45 (4), p.599-607

1994

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Cyclodextrin as Carrier of Peptide Hormones. Conformational and Biological Properties of β-Cyclodextrin/Gastrin Constructs

Journal of the American Chemical Society, 1998-07, Vol.120 (28), p.7030-7038

1998

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Met-195 of the Cholecystokinin-A Receptor Interacts with the Sulfated Tyrosine of Cholecystokinin and Is Crucial for Receptor Transition to High Affinity State

The Journal of biological chemistry, 1998-06, Vol.273 (23), p.14380-14386

1998

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Identification of Two Amino Acids of the Human Cholecystokinin-A Receptor That Interact with the N-terminal Moiety of Cholecystokinin

The Journal of biological chemistry, 1997-01, Vol.272 (5), p.2920-2926

1997

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Evidence for a Direct Interaction between the Penultimate Aspartic Acid of Cholecystokinin and Histidine 207, Located in the Second Extracellular Loop of the Cholecystokinin B Receptor

The Journal of biological chemistry, 1999-08, Vol.274 (33), p.23191-23197

1999

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Cadmium-induced alterations of chlorpropham metabolism in isolated rat hepatocytes

Toxicology (Amsterdam), 1989-12, Vol.59 (2), p.211-223

1989

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Evidence for a functional role of the cholecystokinin-B/gastrin receptor in the human fetal and adult pancreas

Arginine 197 of the cholecystokinin-A receptor binding site interacts with the sulfate of the peptide agonist cholecystokinin

Rhodopsin crystal: new template yielding realistic models of G-protein-coupled receptors?

Transgenic CCK-B/gastrin receptor mediates murine exocrine pancreatic secretion

Probing a Model of a GPCR/Ligand Complex in an Explicit Membrane Environment: The Human Cholecystokinin-1 Receptor

Identification of a Region of the N-Terminal of the Human CCKA Receptor Essential for the High Affinity Interaction with Agonist CCK

A novel mechanism for JAK2 activation by a G protein-coupled receptor, the CCK2R: implication of this signaling pathway in pancreatic tumor models

Modeled Structure of a G-Protein-Coupled Receptor: The Cholecystokinin-1 Receptor

Evidence That Interspecies Polymorphism in the Human and Rat Cholecystokinin Receptor-2 Affects Structure of the Binding Site for the Endogenous Agonist Cholecystokinin

Evidences for a unique conformation of CCK2 receptor recruiting beta-arrestine2

Molecular Mechanism Underlying Partial and Full Agonism Mediated by the Human Cholecystokinin-1 Receptor

Molecular cloning, developmental expression and pharmacological characterization of the CCKB/gastrin receptor in the calf pancreas

Partial Agonism, Neutral Antagonism, and Inverse Agonism at the Human Wild-Type and Constitutively Active Cholecystokinin-2 Receptors

Role of the Extracellular Domains of the Cholecystokinin Receptor in Agonist Binding

Combination of Molecular Modeling, Site-Directed Mutagenesis, and SAR Studies To Delineate the Binding Site of Pyridopyrimidine Antagonists on the Human CCK1 Receptor

The biologically crucial C terminus of cholecystokinin and the non-peptide agonist SR-146,131 share a common binding site in the human CCK1 receptor. Evidence for a crucial role of Met-121 in the activation process

Essential interaction of Egr-1 at an islet-specific response element for basal and gastrin-dependent glucagon gene transactivation in pancreatic alpha-cells

Arginine 336 and Asparagine 333 of the Human Cholecystokinin-A Receptor Binding Site Interact with the Penultimate Aspartic Acid and the C-terminal Amide of Cholecystokinin

Identification of Tyrosine 189 and Asparagine 358 of the Cholecystokinin 2 Receptor in Direct Interaction with the Crucial C-Terminal Amide of Cholecystokinin by Molecular Modeling, Site-Directed Mutagenesis, and Structure/Affinity Studies

Photoaffinity labeling of rat pancreatic cholecystokinin type A receptor antagonist binding sites demonstrates the presence of a truncated cholecystokinin type A receptor

Cyclodextrin as Carrier of Peptide Hormones. Conformational and Biological Properties of β-Cyclodextrin/Gastrin Constructs

Met-195 of the Cholecystokinin-A Receptor Interacts with the Sulfated Tyrosine of Cholecystokinin and Is Crucial for Receptor Transition to High Affinity State

Identification of Two Amino Acids of the Human Cholecystokinin-A Receptor That Interact with the N-terminal Moiety of Cholecystokinin

Evidence for a Direct Interaction between the Penultimate Aspartic Acid of Cholecystokinin and Histidine 207, Located in the Second Extracellular Loop of the Cholecystokinin B Receptor

Cadmium-induced alterations of chlorpropham metabolism in isolated rat hepatocytes

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