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Chiral Oxazolopiperidone Lactams: Versatile Intermediates for the Enantioselective Synthesis of Piperidine-Containing Natural Products

Chemistry : a European journal, 2006-11, Vol.12 (32), p.8198-8207

2006

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Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer’s Disease

Neurotherapeutics, 2020-10, Vol.17 (4), p.1825-1835

2020

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Design and Synthesis of AMPK Activators and GDF15 Inducers

Molecules (Basel, Switzerland), 2023-07, Vol.28 (14), p.5468

2023

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Synthesis, Characterization and HPLC Analysis of the (1 S ,2 S ,5 R )-Diastereomer and the Enantiomer of the Clinical Candidate AR-15512

Molecules (Basel, Switzerland), 2021-02, Vol.26 (4), p.906

2021

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Glycosylation defects, offset by PEPCK-M, drive entosis in breast carcinoma cells

Cell death & disease, 2022-08, Vol.13 (8), p.730-730, Article 730

2022

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mAb-Functionalized Biomimetic MamC-Mediated-Magnetoliposomes as Drug Delivery Systems for Cancer Therapy

International journal of molecular sciences, 2023-09, Vol.24 (18), p.13958

2023

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Insights into the Pharmacokinetics and In Vitro Cell-Based Studies of the Imidazoline I2 Receptor Ligand B06

International journal of molecular sciences, 2022-05, Vol.23 (10), p.5408

2022

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Microarray Analysis Revealed Inflammatory Transcriptomic Changes after LSL60101 Treatment in 5XFAD Mice Model

Genes, 2021-08, Vol.12 (9), p.1315

2021

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An Imidazoline 2 Receptor Ligand Relaxes Mouse Aorta via Off-Target Mechanisms Resistant to Aging

Frontiers in pharmacology, 2022-05, Vol.13, p.826837-826837

2022

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Heterocycle-Based Multicomponent Reactions in Drug Discovery: From Hit Finding to Rational Design

Biomedicines, 2022-06, Vol.10 (7), p.1488

2022

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Enantioselective Synthesis of 3,3-Disubstituted Piperidine Derivatives by Enolate Dialkylation of Phenylglycinol-Derived Oxazolopiperidone Lactams

Journal of organic chemistry, 2007-06, Vol.72 (12), p.4431-4439

2007

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Amelioration of BPSD-Like Phenotype and Cognitive Decline in SAMP8 Mice Model Accompanied by Molecular Changes after Treatment with I2-Imidazoline Receptor Ligand MCR5

Pharmaceutics, 2020-05, Vol.12 (5), p.475

2020

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I2 imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway

GeroScience, 2021-04, Vol.43 (2), p.965-983

2021

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Preclinical Evaluation of an Imidazole-Linked Heterocycle for Alzheimer’s Disease

Pharmaceutics, 2023-09, Vol.15 (10), p.2381

2023

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Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M

Biomedicine & pharmacotherapy, 2020-01, Vol.121, p.109601, Article 109601

2020

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Behavioral and Cognitive Improvement Induced by Novel Imidazoline I2 Receptor Ligands in Female SAMP8 Mice

Neurotherapeutics, 2019-04, Vol.16 (2), p.416-431

2019

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Reseña "La incorporación de criterios medioambientales, sociales y de gobernanza en el ámbito de la valoración inmobiliaria"

Revista de estudios empresariales Jaén, 2024-01 (1), p.211-214

Escolano Asensi, Carmen Victoria

2024

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Triheptanoin supplementation to ketogenic diet curbs cognitive impairment in APP/PS1 mice used as a model of familial Alzheimer's disease

Current Alzheimer research, 2013-03, Vol.10 (3), p.290-297

2013

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Enantioselective Formal Synthesis of (+)-Dihydrocorynantheine and (−)-Dihydrocorynantheol

Journal of organic chemistry, 2009-02, Vol.74 (3), p.1205-1211

2009

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First diastereoselective [3 + 2] cycloaddition reaction of diethyl isocyanomethylphosphonate and maleimides

Organic & biomolecular chemistry, 2013-01, Vol.11 (10), p.1640-1649

2013

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Aryl radical cyclisation onto pyrroles: a divergent synthesis of spiropyrrolidinyloxindoles and pyrroloquinolines

Tetrahedron letters, 2000-11, Vol.41 (46), p.8951-8955

2000

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A practical procedure for the removal of the phenylethanol moiety from phenylglycinol-derived lactams

Tetrahedron: asymmetry, 2010-10, Vol.21 (20), p.2542-2549

2010

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Nitrile Ylides: Generation, Properties and Synthetic Applications

Current organic chemistry, 2007-06, Vol.11 (9), p.741-772

2007

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Facile microwave-assisted synthesis of thioformamides from isocyanides and carbon disulfide

Tetrahedron letters, 2017-07, Vol.58 (28), p.2768-2770

2017

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Disease‐modifying treatment with I2 imidazoline receptor ligand LSL60101 in an Alzheimer's disease mouse model: a comparative study with donepezil

British journal of pharmacology, 2021-08, Vol.178 (15), p.3017-3033

2021

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Chiral Oxazolopiperidone Lactams: Versatile Intermediates for the Enantioselective Synthesis of Piperidine-Containing Natural Products

Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer’s Disease

Design and Synthesis of AMPK Activators and GDF15 Inducers

Synthesis, Characterization and HPLC Analysis of the (1 S ,2 S ,5 R )-Diastereomer and the Enantiomer of the Clinical Candidate AR-15512

Glycosylation defects, offset by PEPCK-M, drive entosis in breast carcinoma cells

mAb-Functionalized Biomimetic MamC-Mediated-Magnetoliposomes as Drug Delivery Systems for Cancer Therapy

Insights into the Pharmacokinetics and In Vitro Cell-Based Studies of the Imidazoline I2 Receptor Ligand B06

Microarray Analysis Revealed Inflammatory Transcriptomic Changes after LSL60101 Treatment in 5XFAD Mice Model

An Imidazoline 2 Receptor Ligand Relaxes Mouse Aorta via Off-Target Mechanisms Resistant to Aging

Heterocycle-Based Multicomponent Reactions in Drug Discovery: From Hit Finding to Rational Design

Enantioselective Synthesis of 3,3-Disubstituted Piperidine Derivatives by Enolate Dialkylation of Phenylglycinol-Derived Oxazolopiperidone Lactams

Amelioration of BPSD-Like Phenotype and Cognitive Decline in SAMP8 Mice Model Accompanied by Molecular Changes after Treatment with I2-Imidazoline Receptor Ligand MCR5

I2 imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway

Preclinical Evaluation of an Imidazole-Linked Heterocycle for Alzheimer’s Disease

Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M

Behavioral and Cognitive Improvement Induced by Novel Imidazoline I2 Receptor Ligands in Female SAMP8 Mice

Reseña "La incorporación de criterios medioambientales, sociales y de gobernanza en el ámbito de la valoración inmobiliaria"

Triheptanoin supplementation to ketogenic diet curbs cognitive impairment in APP/PS1 mice used as a model of familial Alzheimer's disease

Enantioselective Formal Synthesis of (+)-Dihydrocorynantheine and (−)-Dihydrocorynantheol

First diastereoselective [3 + 2] cycloaddition reaction of diethyl isocyanomethylphosphonate and maleimides

Aryl radical cyclisation onto pyrroles: a divergent synthesis of spiropyrrolidinyloxindoles and pyrroloquinolines

A practical procedure for the removal of the phenylethanol moiety from phenylglycinol-derived lactams

Nitrile Ylides: Generation, Properties and Synthetic Applications

Facile microwave-assisted synthesis of thioformamides from isocyanides and carbon disulfide

Disease‐modifying treatment with I2 imidazoline receptor ligand LSL60101 in an Alzheimer's disease mouse model: a comparative study with donepezil

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