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Molecular basis of USP7 inhibition by selective small-molecule inhibitors

Nature (London), 2017-10, Vol.550 (7677), p.481-486

2017

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Elevated Expression of axin2 and hnkd mRNA Provides Evidence That Wnt/β-Catenin Signaling is Activated in Human Colon Tumors

Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (26), p.14973-14978

2001

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Abstract 1335: Dual MCT1/4 inhibition promotes anti-tumor immunity in triple-negative breast cancer

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1335-1335

2021

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The fms-Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor

Science (American Association for the Advancement of Science), 1992-02, Vol.255 (5047), p.989-991

1992

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Regulation of chemotaxis by the platelet-derived growth factor receptor-β

Nature (London), 1994-02, Vol.367 (6462), p.474-476

1994

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Abstract 1268: A novel treatment approach for melanoma by dually targeting MCT1 and MCT4 lactate transporters

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1268-1268

2021

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Characterization of a New Member of the TNF Family Expressed on Antigen Presenting Cells

Biological chemistry, 1999-12, Vol.380 (12), p.1443-1447

1999

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Role of Phosphatidylinositol Kinase in PDGF Receptor Signal Transduction

Science (American Association for the Advancement of Science), 1989-03, Vol.243 (4895), p.1191-1194

1989

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Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin

Proceedings of the National Academy of Sciences - PNAS, 1997-12, Vol.94 (25), p.13921-13926

1997

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1355 Novel pharmacological approach to induce direct killing of cancer and activate antitumor immunity via inhibition of monocarboxylate transporters

Journal for immunotherapy of cancer, 2022, Vol.10 (Suppl 2), p.A1406-A1406

2022

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1381 Lactate modulation in cancer and immune cells is associated with antitumor efficacy of dual MCT1/MCT4 inhibitor NGY-091

Journal for immunotherapy of cancer, 2022, Vol.10 (Suppl 2), p.A1435-A1435

2022

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Tightly regulated long-term erythropoietin expression in vivo using tet-inducible recombinant adeno-associated viral vectors

Human gene therapy, 2002-01, Vol.13 (2), p.335-342

2002

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Abstract 5126: Modulation of lactate in the tumor microenvironment with lactate transporter inhibitor in a melanoma syngeneic mouse model

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5126-5126

2018

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Abstract P3-07-21: Therapeutic efficacy of NGY-091 against triple negative breast cancer is mediated by direct cell killing and activation of antitumor immunity

Cancer research (Chicago, Ill.), 2023-03, Vol.83 (5_Supplement), p.P3-P3-07-21

2023

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Inhibition of PDGF β Receptor Signal Transduction by Coexpression of a Truncated Receptor

Science (American Association for the Advancement of Science), 1991-05, Vol.252 (5007), p.844-848

1991

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Abstract 4053: NGY-B is a novel inhibitor of MCT transporters blocking lactate and glucose metabolisms

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.4053-4053

2022

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Abstract 2652: Efficacy of a small molecule MCT1 and MCT4 transporter inhibitor in cancer

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2652-2652

2022

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A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF

Nature (London), 1988-09, Vol.335 (6185), p.85-87

1988

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β-catenin regulates vascular endothelial growth factor expression in colon cancer

Cancer research (Chicago, Ill.), 2003-06, Vol.63 (12), p.3145-3153

2003

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Retinal Degeneration Is Slowed in Transgenic Rats by AAV-Mediated Delivery of FGF-2

Investigative ophthalmology & visual science, 2000-10, Vol.41 (11), p.3622-3633

2000

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Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

Cell, 1992-05, Vol.69 (3), p.413-423

1992

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Transient immunosuppression allows transgene expression following readministration of adeno-associated viral vectors

Human gene therapy, 1998-03, Vol.9 (4), p.477-485

1998

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Viability of transgenic mice expressing a platelet derived growth factor (PDGF) antagonist in plasma

Journal of investigative medicine, 1996-04, Vol.44 (4), p.139

1996

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cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

Cell, 1991-04, Vol.65 (1), p.75-82

1991

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Molecular basis of USP7 inhibition by selective small-molecule inhibitors

Elevated Expression of axin2 and hnkd mRNA Provides Evidence That Wnt/β-Catenin Signaling is Activated in Human Colon Tumors

Abstract 1335: Dual MCT1/4 inhibition promotes anti-tumor immunity in triple-negative breast cancer

The fms-Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor

Regulation of chemotaxis by the platelet-derived growth factor receptor-β

Abstract 1268: A novel treatment approach for melanoma by dually targeting MCT1 and MCT4 lactate transporters

Characterization of a New Member of the TNF Family Expressed on Antigen Presenting Cells

Role of Phosphatidylinositol Kinase in PDGF Receptor Signal Transduction

Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin

1355 Novel pharmacological approach to induce direct killing of cancer and activate antitumor immunity via inhibition of monocarboxylate transporters

1381 Lactate modulation in cancer and immune cells is associated with antitumor efficacy of dual MCT1/MCT4 inhibitor NGY-091

Tightly regulated long-term erythropoietin expression in vivo using tet-inducible recombinant adeno-associated viral vectors

Abstract 5126: Modulation of lactate in the tumor microenvironment with lactate transporter inhibitor in a melanoma syngeneic mouse model

Abstract P3-07-21: Therapeutic efficacy of NGY-091 against triple negative breast cancer is mediated by direct cell killing and activation of antitumor immunity

Inhibition of PDGF β Receptor Signal Transduction by Coexpression of a Truncated Receptor

Abstract 4053: NGY-B is a novel inhibitor of MCT transporters blocking lactate and glucose metabolisms

Abstract 2652: Efficacy of a small molecule MCT1 and MCT4 transporter inhibitor in cancer

A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF

β-catenin regulates vascular endothelial growth factor expression in colon cancer

Retinal Degeneration Is Slowed in Transgenic Rats by AAV-Mediated Delivery of FGF-2

FT-1101: A Structurally Distinct Pan-BET Bromodomain Inhibitor with Activity in Preclinical Models of Hematologic Malignancies

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

Transient immunosuppression allows transgene expression following readministration of adeno-associated viral vectors

Viability of transgenic mice expressing a platelet derived growth factor (PDGF) antagonist in plasma

cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

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