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A comparison of the TempO-Seq and Affymetrix microarray platform using RTqPCR validation

BMC genomics, 2024-07, Vol.25 (1), p.1-14, Article 669

2024

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Substantiate a read-across hypothesis by using transcriptome data-A case study on volatile diketones

Frontiers in toxicology, 2023-05, Vol.5, p.1155645-1155645

2023

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Inhibition of CD26/Dipeptidyl Peptidase IV Enhances CCL11/Eotaxin-Mediated Recruitment of Eosinophils In Vivo

The Journal of immunology (1950), 2008-07, Vol.181 (2), p.1120-1127

2008

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Threshold of Toxicological Concern-An Update for Non-Genotoxic Carcinogens

Frontiers in toxicology, 2021-06, Vol.3, p.688321-688321

2021

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Potential of the zebrafish (Danio rerio) embryo test to discriminate between chemicals of similar molecular structure—a study with valproic acid and 14 of its analogues

Archives of toxicology, 2022-11, Vol.96 (11), p.3033-3051

2022

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Uncovering the toxicity mechanisms of a series of carboxylic acids in liver cells through computational and experimental approaches

Toxicology (Amsterdam), 2024-05, Vol.504, p.153764-153764, Article 153764

2024

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Towards grouping concepts based on new approach methodologies in chemical hazard assessment: the read-across approach of the EU-ToxRisk project

Archives of toxicology, 2019-12, Vol.93 (12), p.3643-3667

2019

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Combining In Vivo Data with In Silico Predictions for Modeling Hepatic Steatosis by Using Stratified Bagging and Conformal Prediction

Chemical research in toxicology, 2021-02, Vol.34 (2), p.656-668

2021

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Risk assessment for irritating chemicals – Derivation of extrapolation factors

International journal of hygiene and environmental health, 2021-03, Vol.232, p.113668, Article 113668

2021

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Curated human hyperbilirubinemia data and the respective OATP1B1 and 1B3 inhibition predictions

Data in brief, 2017-04, Vol.11 (C), p.204-207

2017

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Integrated In Silico Models for the Prediction of No-Observed-(Adverse)-Effect Levels and Lowest-Observed-(Adverse)-Effect Levels in Rats for Sub-chronic Repeated-Dose Toxicity

Chemical research in toxicology, 2021-02, Vol.34 (2), p.247-257

2021

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RespiraTox – Development of a QSAR model to predict human respiratory irritants

Regulatory toxicology and pharmacology, 2022-02, Vol.128, p.105089-105089, Article 105089

2022

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The application of new HARD-descriptor available from the CORAL software to building up NOAEL models

Food and chemical toxicology, 2018-02, Vol.112, p.544-550

2018

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Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case

European journal of pharmaceutical sciences, 2017-03, Vol.100, p.9-16

2017

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Update of the Cancer Potency Database (CPDB) to enable derivations of Thresholds of Toxicological Concern (TTC) for cancer potency

Food and chemical toxicology, 2023-12, Vol.182, p.114182-114182, Article 114182

2023

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Workshop report: Challenges faced in developing inhalation thresholds of Toxicological Concern (TTC) - State of the science and next steps

Regulatory toxicology and pharmacology, 2023-08, Vol.142, p.105434-105434, Article 105434

2023

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OpenTox predictive toxicology framework: toxicological ontology and semantic media wiki-based OpenToxipedia

Journal of biomedical semantics, 2012-04, Vol.3 Suppl 1 (Suppl 1), p.S7-S7

2012

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Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology

ALTEX, alternatives to animal experimentation, 2020-01, Vol.37 (4), p.579-606

2020

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Corrigendum to “The application of new HARD-descriptor available from the CORAL software to building up NOAEL models” [Food Chem. Toxicol. 112 (2018) 544–550]

Food and chemical toxicology, 2019-06, Vol.128, p.146-146

2019

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Exposure considerations in human safety assessment: Report from an EPAA Partners’ Forum

Regulatory toxicology and pharmacology, 2023-10, Vol.144, p.105483-105483, Article 105483

2023

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Toward implementing virtual control groups in nonclinical safety studies

ALTEX, alternatives to animal experimentation, 2024

2024

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Workshop report on the evaluation of the updated and expanded carcinogen database to support derivation of threshold of toxicological concern values for DNA-reactive carcinogens

ALTEX, 2023-01, Vol.40 (2), p.341

2023

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Inhalation threshold of toxicological concern (TTC) — Structural alerts discriminate high from low repeated-dose inhalation toxicity

Environment international, 2016-03, Vol.88, p.123-132

2016

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NAM-supported read-across: From case studies to regulatory guidance in safety assessment

ALTEX, alternatives to animal experimentation, 2021, Vol.38 (1), p.140-150

2021

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A comparison of the TempO-Seq and Affymetrix microarray platform using RTqPCR validation

Substantiate a read-across hypothesis by using transcriptome data-A case study on volatile diketones

Inhibition of CD26/Dipeptidyl Peptidase IV Enhances CCL11/Eotaxin-Mediated Recruitment of Eosinophils In Vivo

Threshold of Toxicological Concern-An Update for Non-Genotoxic Carcinogens

Potential of the zebrafish (Danio rerio) embryo test to discriminate between chemicals of similar molecular structure—a study with valproic acid and 14 of its analogues

Uncovering the toxicity mechanisms of a series of carboxylic acids in liver cells through computational and experimental approaches

Towards grouping concepts based on new approach methodologies in chemical hazard assessment: the read-across approach of the EU-ToxRisk project

Combining In Vivo Data with In Silico Predictions for Modeling Hepatic Steatosis by Using Stratified Bagging and Conformal Prediction

Risk assessment for irritating chemicals – Derivation of extrapolation factors

Curated human hyperbilirubinemia data and the respective OATP1B1 and 1B3 inhibition predictions

Integrated In Silico Models for the Prediction of No-Observed-(Adverse)-Effect Levels and Lowest-Observed-(Adverse)-Effect Levels in Rats for Sub-chronic Repeated-Dose Toxicity

RespiraTox – Development of a QSAR model to predict human respiratory irritants

The application of new HARD-descriptor available from the CORAL software to building up NOAEL models

Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case

Update of the Cancer Potency Database (CPDB) to enable derivations of Thresholds of Toxicological Concern (TTC) for cancer potency

Workshop report: Challenges faced in developing inhalation thresholds of Toxicological Concern (TTC) - State of the science and next steps

OpenTox predictive toxicology framework: toxicological ontology and semantic media wiki-based OpenToxipedia

Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology

Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action

Corrigendum to “The application of new HARD-descriptor available from the CORAL software to building up NOAEL models” [Food Chem. Toxicol. 112 (2018) 544–550]

Exposure considerations in human safety assessment: Report from an EPAA Partners’ Forum

Toward implementing virtual control groups in nonclinical safety studies

Workshop report on the evaluation of the updated and expanded carcinogen database to support derivation of threshold of toxicological concern values for DNA-reactive carcinogens

Inhalation threshold of toxicological concern (TTC) — Structural alerts discriminate high from low repeated-dose inhalation toxicity

NAM-supported read-across: From case studies to regulatory guidance in safety assessment

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