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New insights on the influence of free d-aspartate metabolism in the mammalian brain during prenatal and postnatal life

Biochimica et biophysica acta. Proteins and proteomics, 2020-10, Vol.1868 (10), p.140471, Article 140471

2020

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Homeostasis of serine enantiomers is disrupted in the post-mortem caudate putamen and cerebrospinal fluid of living Parkinson's disease patients

Neurobiology of disease, 2023-08, Vol.184, p.106203-106203, Article 106203

2023

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The Emerging Role of Altered d-Aspartate Metabolism in Schizophrenia: New Insights From Preclinical Models and Human Studies

Frontiers in psychiatry, 2018-11, Vol.9, p.559-559

2018

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Impact of Serotonin Deficiency on Circadian Dopaminergic Rhythms

International journal of molecular sciences, 2024-06, Vol.25 (12), p.6475

2024

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Blood D-serine levels correlate with aging and dopaminergic treatment in Parkinson's disease

Neurobiology of disease, 2024-03, Vol.192, p.106413-106413, Article 106413

2024

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New insights on the role of free d-aspartate in the mammalian brain

Amino acids, 2012-11, Vol.43 (5), p.1861-1871

2012

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Cerebrospinal fluid and serum d-serine concentrations are unaltered across the whole clinical spectrum of Alzheimer's disease

Biochimica et biophysica acta. Proteins and proteomics, 2020-12, Vol.1868 (12), p.140537-140537, Article 140537

2020

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Dysfunctional d-aspartate metabolism in BTBR mouse model of idiopathic autism

Biochimica et biophysica acta. Proteins and proteomics, 2020-12, Vol.1868 (12), p.140531-140531, Article 140531

2020

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Perturbation of serine enantiomers homeostasis in the striatum of MPTP-lesioned monkeys and mice reflects the extent of dopaminergic midbrain degeneration

Neurobiology of disease, 2023-08, Vol.184, p.106226-106226, Article 106226

2023

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New Evidence on the Role of D-Aspartate Metabolism in Regulating Brain and Endocrine System Physiology: From Preclinical Observations to Clinical Applications

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8718

2020

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78,000-year-old record of Middle and Later stone age innovation in an East African tropical forest

Nature communications, 2018-05, Vol.9 (1), p.1832-8, Article 1832

2018

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Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging

The Journal of neuroscience, 2016-03, Vol.36 (10), p.3064-3078

2016

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High performance liquid chromatography determination of l-glutamate, l-glutamine and glycine content in brain, cerebrospinal fluid and blood serum of patients affected by Alzheimer’s disease

Amino acids, 2021-03, Vol.53 (3), p.435-449

2021

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The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson's disease patients

Scientific reports, 2019-06, Vol.9 (1), p.8898-15, Article 8898

2019

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D-aspartate oxidase gene duplication induces social recognition memory deficit in mice and intellectual disabilities in humans

Translational psychiatry, 2022-08, Vol.12 (1), p.305-305, Article 305

2022

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Analysis of mRNA and Protein Levels of CAP2 , DLG1 and ADAM10 Genes in Post-Mortem Brain of Schizophrenia, Parkinson's and Alzheimer's Disease Patients

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1539

2022

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Quantitative determination of free D-Asp, L-Asp and N-methyl-D-aspartate in mouse brain tissues by chiral separation and Multiple Reaction Monitoring tandem mass spectrometry

PloS one, 2017-06, Vol.12 (6), p.e0179748-e0179748

2017

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Plant bedding construction between 60,000 and 40,000 years ago at Border Cave, South Africa

Quaternary science reviews, 2022-01, Vol.275, p.107280, Article 107280

2022

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Decreased free D-aspartate levels in the blood serum of patients with schizophrenia

Frontiers in psychiatry, 2024-07, Vol.15, p.1408175

2024

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D-Aspartate Prevents Corticostriatal Long-Term Depression and Attenuates Schizophrenia-Like Symptoms Induced by Amphetamine and MK-801

The Journal of neuroscience, 2008-10, Vol.28 (41), p.10404-10414

2008

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Serum dysregulation of serine and glycine metabolism as predictive biomarker for cognitive decline in frail elderly subjects

Translational psychiatry, 2024-07, Vol.14 (1), p.281-13, Article 281

2024

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Rasd2 Modulates Prefronto-Striatal Phenotypes in Humans and 'Schizophrenia-Like Behaviors' in Mice

Neuropsychopharmacology (New York, N.Y.), 2016-02, Vol.41 (3), p.916-927

2016

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Prenatal expression of d-aspartate oxidase causes early cerebral d-aspartate depletion and influences brain morphology and cognitive functions at adulthood

Amino acids, 2020-04, Vol.52 (4), p.597-617

2020

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Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia

Neurobiology of disease, 2010-06, Vol.38 (3), p.434-445

2010

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New insights on the influence of free d-aspartate metabolism in the mammalian brain during prenatal and postnatal life

Homeostasis of serine enantiomers is disrupted in the post-mortem caudate putamen and cerebrospinal fluid of living Parkinson's disease patients

The Emerging Role of Altered d-Aspartate Metabolism in Schizophrenia: New Insights From Preclinical Models and Human Studies

Impact of Serotonin Deficiency on Circadian Dopaminergic Rhythms

Blood D-serine levels correlate with aging and dopaminergic treatment in Parkinson's disease

New insights on the role of free d-aspartate in the mammalian brain

Cerebrospinal fluid and serum d-serine concentrations are unaltered across the whole clinical spectrum of Alzheimer's disease

Dysfunctional d-aspartate metabolism in BTBR mouse model of idiopathic autism

Perturbation of serine enantiomers homeostasis in the striatum of MPTP-lesioned monkeys and mice reflects the extent of dopaminergic midbrain degeneration

New Evidence on the Role of D-Aspartate Metabolism in Regulating Brain and Endocrine System Physiology: From Preclinical Observations to Clinical Applications

78,000-year-old record of Middle and Later stone age innovation in an East African tropical forest

Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging

Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking d-aspartate oxidase activity

High performance liquid chromatography determination of l-glutamate, l-glutamine and glycine content in brain, cerebrospinal fluid and blood serum of patients affected by Alzheimer’s disease

The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson's disease patients

D-aspartate oxidase gene duplication induces social recognition memory deficit in mice and intellectual disabilities in humans

Analysis of mRNA and Protein Levels of CAP2 , DLG1 and ADAM10 Genes in Post-Mortem Brain of Schizophrenia, Parkinson's and Alzheimer's Disease Patients

Quantitative determination of free D-Asp, L-Asp and N-methyl-D-aspartate in mouse brain tissues by chiral separation and Multiple Reaction Monitoring tandem mass spectrometry

Plant bedding construction between 60,000 and 40,000 years ago at Border Cave, South Africa

Decreased free D-aspartate levels in the blood serum of patients with schizophrenia

D-Aspartate Prevents Corticostriatal Long-Term Depression and Attenuates Schizophrenia-Like Symptoms Induced by Amphetamine and MK-801

Serum dysregulation of serine and glycine metabolism as predictive biomarker for cognitive decline in frail elderly subjects

Rasd2 Modulates Prefronto-Striatal Phenotypes in Humans and 'Schizophrenia-Like Behaviors' in Mice

Prenatal expression of d-aspartate oxidase causes early cerebral d-aspartate depletion and influences brain morphology and cognitive functions at adulthood

Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia

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