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A population pharmacokinetic model using allometric scaling for baricitinib in patients with juvenile idiopathic arthritis

CPT: pharmacometrics and systems pharmacology, 2024-06, Vol.13 (6), p.970-981

2024

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Donanemab exposure and efficacy relationship using modeling in Alzheimer's disease

Alzheimer's & dementia : translational research & clinical interventions, 2023-04, Vol.9 (2), p.e12404-n/a

2023

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Methodological Comparison of In Vitro Binding Parameter Estimation: Sequential vs. Simultaneous Non-linear Regression

Pharmaceutical research, 2010-05, Vol.27 (5), p.866-877

2010

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Mechanism-based inactivation of CYP3A by HIV protease inhibitors

The Journal of pharmacology and experimental therapeutics, 2005-02, Vol.312 (2), p.583

2005

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PK/PD modeling links accelerated resolution of COVID‐19‐related clinical symptoms to SARS‐CoV‐2 viral load reduction in patients following treatment with Bamlanivimab alone or Bamlanivimab and Etesevimab together

CPT: pharmacometrics and systems pharmacology, 2022-06, Vol.11 (6), p.721-730

2022

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Relationship Between Exposure to Prasugrel Active Metabolite and Clinical Outcomes in the TRITON-TIMI 38 Substudy

Journal of clinical pharmacology, 2012-06, Vol.52 (6), p.789-797

2012

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Population Pharmacokinetic Analyses to Evaluate the Influence of Intrinsic and Extrinsic Factors on Exposure of Prasugrel Active Metabolite in TRITON-TIMI 38

Journal of clinical pharmacology, 2009-08, Vol.49 (8), p.984-998

2009

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Integrated Analysis of Pharmacokinetic Data Across Multiple Clinical Pharmacology Studies of Prasugrel, a New Thienopyridine Antiplatelet Agent

Journal of clinical pharmacology, 2011-03, Vol.51 (3), p.321-332

2011

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Effect of Atorvastatin on the Pharmacokinetics and Pharmacodynamics of Prasugrel and Clopidogrel in Healthy Subjects

Pharmacotherapy, 2008-12, Vol.28 (12), p.1483-1493

2008

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Prasugrel, a New Thienopyridine Antiplatelet Drug, Weakly Inhibits Cytochrome P450 2B6 in Humans

Journal of clinical pharmacology, 2008-01, Vol.48 (1), p.53-59

2008

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Inhibition of platelet aggregation with prasugrel and clopidogrel: An integrated analysis in 846 subjects

Platelets (Edinburgh), 2009-01, Vol.20 (5), p.316-327

2009

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Prediction of Prasugrel Active Metabolite Concentrations From 2 Downstream Inactive Metabolite Concentrations Using Multilinear Regression Analysis

Journal of clinical pharmacology, 2009-08, Vol.49 (8), p.973-983

2009

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Effect of Age on the Pharmacokinetics and Pharmacodynamics of Prasugrel during Multiple Dosing: An Open-Label, Single-Sequence, Clinical Trial

Drugs & aging, 2009-01, Vol.26 (9), p.781-790

2009

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Phase I and pharmacokinetic study of LY309887: a specific inhibitor of purine biosynthesis

Cancer chemotherapy and pharmacology, 2001-06, Vol.47 (6), p.525-531

2001

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Effect of ranitidine on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel

Current Medical Research and Opinion, 2008, Vol.24 (8), p.2251-2257

2008

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Optimal clinical trial design based on a dichotomous Markov-chain mixed-effect sleep model

Journal of pharmacokinetics and pharmacodynamics, 2014-12, Vol.41 (6), p.639-654

2014

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Simultaneous optimal experimental design for in vitro binding parameter estimation

Journal of pharmacokinetics and pharmacodynamics, 2013-10, Vol.40 (5), p.573-585

2013

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Human transcriptome array for high-throughput clinical studies

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (9), p.3707-3712

2011

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Clinical microfluidics for neutrophil genomics and proteomics

Nature medicine, 2010-09, Vol.16 (9), p.1042-1047

2010

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Non-Cognitive Skills and Factors in Educational Attainment

1, 2016

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A population pharmacokinetic model using allometric scaling for baricitinib in patients with juvenile idiopathic arthritis

Donanemab exposure and efficacy relationship using modeling in Alzheimer's disease

Methodological Comparison of In Vitro Binding Parameter Estimation: Sequential vs. Simultaneous Non-linear Regression

Mechanism-based inactivation of CYP3A by HIV protease inhibitors

PK/PD modeling links accelerated resolution of COVID‐19‐related clinical symptoms to SARS‐CoV‐2 viral load reduction in patients following treatment with Bamlanivimab alone or Bamlanivimab and Etesevimab together

Relationship Between Exposure to Prasugrel Active Metabolite and Clinical Outcomes in the TRITON-TIMI 38 Substudy

Population Pharmacokinetic Analyses to Evaluate the Influence of Intrinsic and Extrinsic Factors on Exposure of Prasugrel Active Metabolite in TRITON-TIMI 38

Integrated Analysis of Pharmacokinetic Data Across Multiple Clinical Pharmacology Studies of Prasugrel, a New Thienopyridine Antiplatelet Agent

Effect of Atorvastatin on the Pharmacokinetics and Pharmacodynamics of Prasugrel and Clopidogrel in Healthy Subjects

Prasugrel, a New Thienopyridine Antiplatelet Drug, Weakly Inhibits Cytochrome P450 2B6 in Humans

Inhibition of platelet aggregation with prasugrel and clopidogrel: An integrated analysis in 846 subjects

Prediction of Prasugrel Active Metabolite Concentrations From 2 Downstream Inactive Metabolite Concentrations Using Multilinear Regression Analysis

Effect of Age on the Pharmacokinetics and Pharmacodynamics of Prasugrel during Multiple Dosing: An Open-Label, Single-Sequence, Clinical Trial

Phase I and pharmacokinetic study of LY309887: a specific inhibitor of purine biosynthesis

Effect of ranitidine on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel

Optimal clinical trial design based on a dichotomous Markov-chain mixed-effect sleep model

Simultaneous optimal experimental design for in vitro binding parameter estimation

Human transcriptome array for high-throughput clinical studies

Clinical microfluidics for neutrophil genomics and proteomics

Non-Cognitive Skills and Factors in Educational Attainment

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