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Finding the genes for fragile bones

eLife, 2022-12, Vol.11

Kague, Erika

2022

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Wnt signalling controls the response to mechanical loading during zebrafish joint development

Development (Cambridge), 2017-08, Vol.144 (15), p.2798-2809

2017

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Skeletogenic fate of zebrafish cranial and trunk neural crest

PloS one, 2012-11, Vol.7 (11), p.e47394-e47394

2012

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Zebrafish as an Emerging Model for Osteoporosis: A Primary Testing Platform for Screening New Osteo-Active Compounds

Frontiers in endocrinology (Lausanne), 2019-01, Vol.10, p.6-6

2019

Volltextzugriff (PDF)

Functional Validation of Osteoporosis Genetic Findings Using Small Fish Models

Genes, 2022-01, Vol.13 (2), p.279

2022

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Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish

The FASEB journal, 2019-08, Vol.33 (8), p.9116-9130

2019

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Dominating lengthscales of zebrafish collective behaviour

PLoS computational biology, 2022-01, Vol.18 (1), p.e1009394-e1009394

2022

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Giantin-knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression

Journal of cell science, 2017-12, Vol.130 (24), p.4132-4143

2017

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Editorial: Fish as model organism for skeletal diseases

Frontiers in endocrinology (Lausanne), 2023-11, Vol.14, p.1331690-1331690

2023

Volltextzugriff (PDF)

Osterix/Sp7 limits cranial bone initiation sites and is required for formation of sutures

Developmental biology, 2016-05, Vol.413 (2), p.160-172

2016

Volltextzugriff (PDF)

3D assessment of intervertebral disc degeneration in zebrafish identifies changes in bone density that prime disc disease

Bone research, 2021-08, Vol.9 (1), p.39-39

2021

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The genetic overlap between osteoporosis and craniosynostosis

Frontiers in endocrinology (Lausanne), 2022-09, Vol.13, p.1020821-1020821

2022

Volltextzugriff (PDF)

Transformed notochordal cells trigger chronic wounds in zebrafish, destabilizing the vertebral column and bone homeostasis

Disease models & mechanisms, 2021-03, Vol.14 (3)

2021

Volltextzugriff (PDF)

Wnt16 Elicits a Protective Effect Against Fractures and Supports Bone Repair in Zebrafish

JBMR plus, 2021-03, Vol.5 (3), p.e10461-n/a

2021

Volltextzugriff (PDF)

BMPs regulate msx gene expression in the dorsal neuroectoderm of Drosophila and vertebrates by distinct mechanisms

PLoS genetics, 2014-09, Vol.10 (9), p.e1004625-e1004625

2014

Volltextzugriff (PDF)

Perspective of the GEMSTONE Consortium on Current and Future Approaches to Functional Validation for Skeletal Genetic Disease Using Cellular, Molecular and Animal-Modeling Techniques

Frontiers in endocrinology (Lausanne), 2021-11, Vol.12, p.731217-731217

2021

Volltextzugriff (PDF)

Osteomodulin downregulation is associated with osteoarthritis development

Bone research, 2023-09, Vol.11 (1), p.49-49

2023

Volltextzugriff (PDF)

Opportunities and Challenges in Functional Genomics Research in Osteoporosis: Report From a Workshop Held by the Causes Working Group of the Osteoporosis and Bone Research Academy of the Royal Osteoporosis Society on October 5th 2020

Frontiers in endocrinology (Lausanne), 2021-02, Vol.11, p.630875-630875

2021

Volltextzugriff (PDF)

Parallel platform for rapid functional screening of Osteoarthritis associated genes

Bone Reports, 2020-10, Vol.13, p.100633, Article 100633

2020

Volltextzugriff (PDF)

Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women

Nature communications, 2021-01, Vol.12 (1), p.654-11, Article 654

2021

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Welfare Assessment of Adult Laboratory Zebrafish: A Practical Guide

Zebrafish, 2021-08, Vol.18 (4), p.282-292

2021

Volltextzugriff (PDF)

Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish

The FASEB journal, 2019-08, Vol.33 (8), p.9116-9130

2019

Volltextzugriff (PDF)

The mechanical impact of col11a2 loss on joints; col11a2 mutant zebrafish show changes to joint development and function, which leads to early-onset osteoarthritis

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2018-09, Vol.373 (1759)

2018

Volltextzugriff (PDF)

Finite element and deformation analyses predict pattern of bone failure in loaded zebrafish spines

Journal of the Royal Society interface, 2019-11, Vol.16 (160), p.20190430

2019

Volltextzugriff (PDF)

CD105 is regulated by hsa-miR-1287 and its expression is inversely correlated with osteopotential in SHED

Bone (New York, N.Y.), 2018-01, Vol.106, p.112-120

2018

Volltextzugriff (PDF)

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Finding the genes for fragile bones

Wnt signalling controls the response to mechanical loading during zebrafish joint development

Skeletogenic fate of zebrafish cranial and trunk neural crest

Zebrafish as an Emerging Model for Osteoporosis: A Primary Testing Platform for Screening New Osteo-Active Compounds

Functional Validation of Osteoporosis Genetic Findings Using Small Fish Models

Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish

Dominating lengthscales of zebrafish collective behaviour

Giantin-knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression

Editorial: Fish as model organism for skeletal diseases

Osterix/Sp7 limits cranial bone initiation sites and is required for formation of sutures

3D assessment of intervertebral disc degeneration in zebrafish identifies changes in bone density that prime disc disease

The genetic overlap between osteoporosis and craniosynostosis

Transformed notochordal cells trigger chronic wounds in zebrafish, destabilizing the vertebral column and bone homeostasis

Wnt16 Elicits a Protective Effect Against Fractures and Supports Bone Repair in Zebrafish

BMPs regulate msx gene expression in the dorsal neuroectoderm of Drosophila and vertebrates by distinct mechanisms

Perspective of the GEMSTONE Consortium on Current and Future Approaches to Functional Validation for Skeletal Genetic Disease Using Cellular, Molecular and Animal-Modeling Techniques

Osteomodulin downregulation is associated with osteoarthritis development

Opportunities and Challenges in Functional Genomics Research in Osteoporosis: Report From a Workshop Held by the Causes Working Group of the Osteoporosis and Bone Research Academy of the Royal Osteoporosis Society on October 5th 2020

Parallel platform for rapid functional screening of Osteoarthritis associated genes

Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women

Welfare Assessment of Adult Laboratory Zebrafish: A Practical Guide

Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish

The mechanical impact of col11a2 loss on joints; col11a2 mutant zebrafish show changes to joint development and function, which leads to early-onset osteoarthritis

Finite element and deformation analyses predict pattern of bone failure in loaded zebrafish spines

CD105 is regulated by hsa-miR-1287 and its expression is inversely correlated with osteopotential in SHED

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