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RNA Polymerase IV Functions in Paramutation in Zea mays

Science (American Association for the Advancement of Science), 2009-02, Vol.323 (5918), p.1201-1205

2009

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Nascent transcription affected by RNA polymerase IV in Zea mays

Genetics (Austin), 2015-04, Vol.199 (4), p.1107-1125

2015

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Paramutation: a process for acquiring trans-generational regulatory states

Current opinion in plant biology, 2011-04, Vol.14 (2), p.210-216

2011

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Diversity of Pol IV function is defined by mutations at the maize rmr7 locus

PLoS genetics, 2009-11, Vol.5 (11), p.e1000706-e1000706

2009

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Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2‑((4-(Benzo[d]thiazol-5-ylamino)-6‑(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases

Journal of medicinal chemistry, 2019-07, Vol.62 (14), p.6482-6494

2019

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Production and processing of siRNA precursor transcripts from the highly repetitive maize genome

PLoS genetics, 2009-08, Vol.5 (8), p.e1000598-e1000598

2009

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Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors

ACS medicinal chemistry letters, 2016-03, Vol.7 (3), p.217-222

2016

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Maize RNA Polymerase IV Defines trans-Generational Epigenetic Variation

The Plant cell, 2013-03, Vol.25 (3), p.808-819

2013

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Ectopic T cell receptor-α locus control region activity in B cells is suppressed by direct linkage to two flanking genes at once

PloS one, 2010-11, Vol.5 (11), p.e15527-e15527

2010

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Identification of a Selective Nonpeptide Antagonist of the Anaphylatoxin C3a Receptor That Demonstrates Antiinflammatory Activity in Animal Models

The Journal of immunology (1950), 2001-05, Vol.166 (10), p.6341-6348

2001

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Sherloc: a comprehensive refinement of the ACMG–AMP variant classification criteria

Genetics in medicine, 2017-10, Vol.19 (10), p.1105-1117

2017

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Potent and Selective Inhibition of Human Cathepsin K Leads to Inhibition of Bone Resorption In Vivo in a Nonhuman Primate

Journal of bone and mineral research, 2001-10, Vol.16 (10), p.1739-1746

2001

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Benzyl 2-Cyano-3,3-Dimethyl-1-pyrrolidinecarboxylate, a Versatile Intermediate for the Synthesis of 3,3-Dimethylproline Derivatives

Journal of organic chemistry, 2008-05, Vol.73 (10), p.3946-3949

2008

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2-Aminomethyl piperidines as novel urotensin-II receptor antagonists

Bioorganic & medicinal chemistry, 2008-05, Vol.18 (9), p.2860-2864

2008

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Structure Activity Relationships of 5-, 6-, and 7-Methyl-Substituted Azepan-3-one Cathepsin K Inhibitors

Journal of medicinal chemistry, 2006-03, Vol.49 (5), p.1597-1612

2006

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1,3-Diarylindan-2-carboxylic Acids, Potent and Selective Non-Peptide Endothelin Receptor Antagonists

Journal of medicinal chemistry, 1994-05, Vol.37 (11), p.1553-1557

1994

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Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase

Bioorganic & medicinal chemistry, 1997-01, Vol.5 (1), p.49-64

1997

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Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid‑4 (TRPV4)

Journal of medicinal chemistry, 2018-11, Vol.61 (21), p.9738-9755

2018

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Alternative polymerase genome regulation in Zea mays

Erhard, Karl Francis

2012

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Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid‑4 with in Vivo Activity in a Pulmonary Edema Model

Journal of medicinal chemistry, 2018-12, Vol.61 (24), p.11209-11220

2018

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Identification, Synthesis, and Characterization of a Major Circulating Human Metabolite of TRPV4 Antagonist GSK2798745

ACS medicinal chemistry letters, 2021-09, Vol.12 (9), p.1498-1502

2021

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Conformationally Constrained 1,3-Diamino Ketones: A Series of Potent Inhibitors of the Cysteine Protease Cathepsin K

Journal of medicinal chemistry, 1998-09, Vol.41 (19), p.3563-3567

1998

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Phenylbutyrates as potent, orally bioavailable vitronectin receptor (integrin αvβ3) antagonists

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (8), p.1483-1486

2003

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Determining the clinical value of germline genetic testing coupled with tumor mutation profiling

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.1577-1577

2017

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RNA Polymerase IV Functions in Paramutation in Zea mays

Nascent transcription affected by RNA polymerase IV in Zea mays

Paramutation: a process for acquiring trans-generational regulatory states

Diversity of Pol IV function is defined by mutations at the maize rmr7 locus

Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2‑((4-(Benzo[d]thiazol-5-ylamino)-6‑(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases

Production and processing of siRNA precursor transcripts from the highly repetitive maize genome

Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors

Maize RNA Polymerase IV Defines trans-Generational Epigenetic Variation

Ectopic T cell receptor-α locus control region activity in B cells is suppressed by direct linkage to two flanking genes at once

Identification of a Selective Nonpeptide Antagonist of the Anaphylatoxin C3a Receptor That Demonstrates Antiinflammatory Activity in Animal Models

Sherloc: a comprehensive refinement of the ACMG–AMP variant classification criteria

Potent and Selective Inhibition of Human Cathepsin K Leads to Inhibition of Bone Resorption In Vivo in a Nonhuman Primate

Benzyl 2-Cyano-3,3-Dimethyl-1-pyrrolidinecarboxylate, a Versatile Intermediate for the Synthesis of 3,3-Dimethylproline Derivatives

2-Aminomethyl piperidines as novel urotensin-II receptor antagonists

Structure Activity Relationships of 5-, 6-, and 7-Methyl-Substituted Azepan-3-one Cathepsin K Inhibitors

1,3-Diarylindan-2-carboxylic Acids, Potent and Selective Non-Peptide Endothelin Receptor Antagonists

Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase

Discovery of Orally Active Nonpeptide Vitronectin Receptor Antagonists Based on a 2-Benzazepine Gly-Asp Mimetic

Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid‑4 (TRPV4)

Alternative polymerase genome regulation in Zea mays

Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid‑4 with in Vivo Activity in a Pulmonary Edema Model

Identification, Synthesis, and Characterization of a Major Circulating Human Metabolite of TRPV4 Antagonist GSK2798745

Conformationally Constrained 1,3-Diamino Ketones: A Series of Potent Inhibitors of the Cysteine Protease Cathepsin K

Phenylbutyrates as potent, orally bioavailable vitronectin receptor (integrin αvβ3) antagonists

Determining the clinical value of germline genetic testing coupled with tumor mutation profiling

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