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Treatment of allergic asthma: modulation of Th2 cells and their responses

Respiratory research, 2011-08, Vol.12 (112), p.114-114, Article 114

2011

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Design and characterization of Zweimab and Doppelmab, high affinity dual antagonistic anti-TSLP/IL13 bispecific antibodies

Biochemical and biophysical research communications, 2018-09, Vol.504 (1), p.19-24

2018

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Development of a novel severe triple allergen asthma model in mice which is resistant to dexamethasone and partially resistant to TLR7 and TLR9 agonist treatment

PloS one, 2014-03, Vol.9 (3), p.e91223

2014

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Helminths, allergic disorders and IgE‐mediated immune responses: Where do we stand?

European Journal of Immunology, 2007-05, Vol.37 (5), p.1170-1173

Erb, Klaus J.

2007

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The Use of Mouse Asthma Models to Successfully Discover and Develop Novel Drugs

International archives of allergy and immunology, 2017-07, Vol.173 (2), p.61-70

2017

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Effects of a Low-Molecular-Weight CCR-3 Antagonist on Chronic Experimental Asthma

American journal of respiratory cell and molecular biology, 2007-01, Vol.36 (1), p.61-67

2007

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Tiotropium bromide inhibits relapsing allergic asthma in BALB/c mice

Pulmonary pharmacology & therapeutics, 2014-02, Vol.27 (1), p.44-51

2014

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Helminth infection modulates the development of allergen‐induced airway inflammation

International immunology, 2004-04, Vol.16 (4), p.585-596

2004

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Can helminths or helminth-derived products be used in humans to prevent or treat allergic diseases?

Trends in immunology, 2009-02, Vol.30 (2), p.75-82

Erb, Klaus J

2009

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The absence of mrp4 has no effect on the recruitment of neutrophils and eosinophils into the lung after LPS, cigarette smoke or allergen challenge

PloS one, 2013-04, Vol.8 (4), p.e61193-e61193

2013

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Tiotropium Attenuates Virus-Induced Pulmonary Inflammation in Cigarette Smoke-Exposed Mice

The Journal of pharmacology and experimental therapeutics, 2016-06, Vol.357 (3), p.606-618

2016

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Infection with Toxoplasma gondii Reduces Established and Developing Th2 Responses Induced by Nippostrongylus brasiliensis Infection

Infection and Immunity, 2004-07, Vol.72 (7), p.3812-3822

2004

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Prerequisites for the pharmaceutical industry to develop and commercialise helminths and helminth-derived product therapy

International journal for parasitology, 2013-03, Vol.43 (3-4), p.319-325

2013

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Neutralization of both IL-1α/IL-1β plays a major role in suppressing combined cigarette smoke/virus-induced pulmonary inflammation in mice

Pulmonary pharmacology & therapeutics, 2017-06, Vol.44, p.96-105

2017

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Modeling Pulmonary Disease Pathways Using Recombinant Adeno-Associated Virus 6.2

American journal of respiratory cell and molecular biology, 2015-09, Vol.53 (3), p.291-302

2015

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Inhibition of the IL-4/IL-13 receptor system prevents allergic sensitization without affecting established allergy in a mouse model for allergic asthma

Journal of allergy and clinical immunology, 2003-06, Vol.111 (6), p.1361-1369

2003

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Induction, exacerbation and inhibition of allergic and autoimmune diseases by infection

Trends in immunology, 2005-05, Vol.26 (5), p.260-267

2005

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Helminth-derived Products Inhibit the Development of Allergic Responses in Mice

American journal of respiratory and critical care medicine, 2007-02, Vol.175 (4), p.336-344

2007

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Expression of selectin ligands on murine effector and IL‐10‐producing CD4+ T cells from non‐infected and infected tissues

European journal of immunology, 2004-11, Vol.34 (11), p.3070-3081

2004

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BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells

The Journal of pharmacology and experimental therapeutics, 2016-06, Vol.357 (3), p.554-561

2016

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Novel vaccines protecting against the development of allergic disorders: a double-edged sword?

Current Opinion in Immunology, 2002-10, Vol.14 (5), p.633-643

2002

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Induced Syk deletion leads to suppressed allergic responses but has no effect on neutrophil or monocyte migration in vivo

European journal of immunology, 2011-11, Vol.41 (11), p.3208-3218

2011

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TLR agonist mediated suppression of allergic responses is associated with increased innate inflammation in the airways

Pulmonary pharmacology & therapeutics, 2011-04, Vol.24 (2), p.203-214

2011

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Mice Deficient in Nuclear Factor of Activated T-Cell Transcription Factor c2 Mount Increased Th2 Responses after Infection with Nippostrongylus brasiliensis and Decreased Th1 Responses after Mycobacterial Infection

Infection and Immunity, 2003-11, Vol.71 (11), p.6641-6647

2003

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Infection with the Helminth Nippostrongylus brasiliensis Does Not Interfere with Efficient Elimination of Mycobacterium bovis BCG from the Lungs of Mice

Clinical and Diagnostic Laboratory Immunology, 2002-05, Vol.9 (3), p.727-730

2002

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Treatment of allergic asthma: modulation of Th2 cells and their responses

Design and characterization of Zweimab and Doppelmab, high affinity dual antagonistic anti-TSLP/IL13 bispecific antibodies

Development of a novel severe triple allergen asthma model in mice which is resistant to dexamethasone and partially resistant to TLR7 and TLR9 agonist treatment

Helminths, allergic disorders and IgE‐mediated immune responses: Where do we stand?

The Use of Mouse Asthma Models to Successfully Discover and Develop Novel Drugs

Effects of a Low-Molecular-Weight CCR-3 Antagonist on Chronic Experimental Asthma

Tiotropium bromide inhibits relapsing allergic asthma in BALB/c mice

Helminth infection modulates the development of allergen‐induced airway inflammation

Can helminths or helminth-derived products be used in humans to prevent or treat allergic diseases?

The absence of mrp4 has no effect on the recruitment of neutrophils and eosinophils into the lung after LPS, cigarette smoke or allergen challenge

Tiotropium Attenuates Virus-Induced Pulmonary Inflammation in Cigarette Smoke-Exposed Mice

Infection with Toxoplasma gondii Reduces Established and Developing Th2 Responses Induced by Nippostrongylus brasiliensis Infection

Prerequisites for the pharmaceutical industry to develop and commercialise helminths and helminth-derived product therapy

Neutralization of both IL-1α/IL-1β plays a major role in suppressing combined cigarette smoke/virus-induced pulmonary inflammation in mice

Modeling Pulmonary Disease Pathways Using Recombinant Adeno-Associated Virus 6.2

Inhibition of the IL-4/IL-13 receptor system prevents allergic sensitization without affecting established allergy in a mouse model for allergic asthma

Induction, exacerbation and inhibition of allergic and autoimmune diseases by infection

Helminth-derived Products Inhibit the Development of Allergic Responses in Mice

Expression of selectin ligands on murine effector and IL‐10‐producing CD4+ T cells from non‐infected and infected tissues

BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells

Novel vaccines protecting against the development of allergic disorders: a double-edged sword?

Induced Syk deletion leads to suppressed allergic responses but has no effect on neutrophil or monocyte migration in vivo

TLR agonist mediated suppression of allergic responses is associated with increased innate inflammation in the airways

Mice Deficient in Nuclear Factor of Activated T-Cell Transcription Factor c2 Mount Increased Th2 Responses after Infection with Nippostrongylus brasiliensis and Decreased Th1 Responses after Mycobacterial Infection

Infection with the Helminth Nippostrongylus brasiliensis Does Not Interfere with Efficient Elimination of Mycobacterium bovis BCG from the Lungs of Mice

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