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Cellular Uptake and Efflux of Azithromycin, Erythromycin, Clarithromycin, Telithromycin, and Cethromycin

Antimicrobial Agents and Chemotherapy, 2005-06, Vol.49 (6), p.2372-2377

2005

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Correlation of ex vivo cytokine secretion profiles with scoring indices in ulcerative colitis

European journal of clinical investigation, 2023-12, Vol.53 (12), p.e14070-n/a

2023

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Impairment of lysosomal functions by azithromycin and chloroquine contributes to anti-inflammatory phenotype

Cellular immunology, 2012-09, Vol.279 (1), p.78-86

2012

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Unprecedented Epimerization of an Azithromycin Analogue: Synthesis, Structure and Biological Activity of 2'-Dehydroxy-5″-Epi-Azithromycin

Molecules (Basel, Switzerland), 2022-02, Vol.27 (3), p.1034

2022

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Translational pathology in drug discovery

Frontiers in pharmacology, 2024-06, Vol.15, p.1409092

2024

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Azithromycin drives in vitro GM-CSF/IL-4-induced differentiation of human blood monocytes toward dendritic-like cells with regulatory properties

Journal of leukocyte biology, 2012-02, Vol.91 (2), p.229-243

2012

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Claudins: Beyond Tight Junctions in Human IBD and Murine Models

Frontiers in pharmacology, 2021-11, Vol.12, p.682614-682614

2021

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A novel class of fast‐acting antimalarial agents: Substituted 15‐membered azalides

British journal of pharmacology, 2021-01, Vol.178 (2), p.363-377

2021

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Anti-inflammatory mechanism of action of azithromycin in LPS-stimulated J774A.1 cells

Pharmacological research, 2012-10, Vol.66 (4), p.357-362

2012

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Characterization of rhodamine-123, calcein and 5(6)-carboxy-2′,7′-dichlorofluorescein (CDCF) export via MRP2 (ABCC2) in MES-SA and A549 cells

European journal of pharmaceutical sciences, 2011-08, Vol.43 (5), p.359-369

2011

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Claudin-3 and Clara Cell 10 kDa Protein as Early Signals of Cigarette Smoke–Induced Epithelial Injury along Alveolar Ducts

Toxicologic pathology, 2012-12, Vol.40 (8), p.1169-1187

2012

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Macrolide antibiotics broadly and distinctively inhibit cytokine and chemokine production by COPD sputum cells in vitro

Pharmacological research, 2011-05, Vol.63 (5), p.389-397

2011

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Intensity of macrolide anti-inflammatory activity in J774A.1 cells positively correlates with cellular accumulation and phospholipidosis

Pharmacological research, 2011-09, Vol.64 (3), p.298-307

2011

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Fluorescently labeled macrolides as a tool for monitoring cellular and tissue distribution of azithromycin

Pharmacological research, 2012-10, Vol.66 (4), p.332-342

2012

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The design of novel classes of macrolides for neutrophil-dominated inflammatory diseases

Future medicinal chemistry, 2014-04, Vol.6 (6), p.657-674

2014

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N′-Substituted-2′-O,3′-N-carbonimidoyl Bridged Macrolides: Novel Anti-inflammatory Macrolides without Antimicrobial Activity

Journal of medicinal chemistry, 2012-07, Vol.55 (13), p.6111-6123

2012

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Clarithromycin suppresses airway hyperresponsiveness and inflammation in mouse models of asthma

European journal of pharmacology, 2009-08, Vol.616 (1), p.236-243

2009

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Azithromycin inhibits macrophage interleukin-1β production through inhibition of activator protein-1 in lipopolysaccharide-induced murine pulmonary neutrophilia

International immunopharmacology, 2011-04, Vol.11 (4), p.424-434

2011

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Synthesis, activity and pharmacokinetics of novel antibacterial 15-membered ring macrolones

European journal of medicinal chemistry, 2011-08, Vol.46 (8), p.3388-3397

2011

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Novel 8a-aza-8a-homoerythromycin—4″-(3-substituted-amino)propionates with broad spectrum antibacterial activity

Bioorganic & medicinal chemistry letters, 2010-06, Vol.20 (11), p.3244-3249

2010

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Valosin containing protein (VCP) interacts with macrolide antibiotics without mediating their anti-inflammatory activities

European journal of pharmacology, 2012-02, Vol.677 (1-3), p.163-172

2012

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Immunomodulatory effects of azithromycin on serum amyloid A production in lipopolysaccharide-induced endotoxemia in mice

Journal of antibiotics, 2011-07, Vol.64 (7), p.515-517

2011

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Differences in assessment of macrolide interaction with human MDR1 (ABCB1, P-gp) using rhodamine-123 efflux, ATPase activity and cellular accumulation assays

European journal of pharmaceutical sciences, 2010-09, Vol.41 (1), p.86-95

2010

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Anti-inflammatory effects of macrolide antibiotics

European Journal of Pharmacology, 2001-10, Vol.429 (1), p.209-229

2001

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Azithromycin: Mechanisms of action and their relevance for clinical applications

Pharmacology & therapeutics (Oxford), 2014-08, Vol.143 (2), p.225-245

2014

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Cellular Uptake and Efflux of Azithromycin, Erythromycin, Clarithromycin, Telithromycin, and Cethromycin

Correlation of ex vivo cytokine secretion profiles with scoring indices in ulcerative colitis

Impairment of lysosomal functions by azithromycin and chloroquine contributes to anti-inflammatory phenotype

Unprecedented Epimerization of an Azithromycin Analogue: Synthesis, Structure and Biological Activity of 2'-Dehydroxy-5″-Epi-Azithromycin

Translational pathology in drug discovery

Azithromycin drives in vitro GM-CSF/IL-4-induced differentiation of human blood monocytes toward dendritic-like cells with regulatory properties

Claudins: Beyond Tight Junctions in Human IBD and Murine Models

A novel class of fast‐acting antimalarial agents: Substituted 15‐membered azalides

Anti-inflammatory mechanism of action of azithromycin in LPS-stimulated J774A.1 cells

Characterization of rhodamine-123, calcein and 5(6)-carboxy-2′,7′-dichlorofluorescein (CDCF) export via MRP2 (ABCC2) in MES-SA and A549 cells

Claudin-3 and Clara Cell 10 kDa Protein as Early Signals of Cigarette Smoke–Induced Epithelial Injury along Alveolar Ducts

Macrolide antibiotics broadly and distinctively inhibit cytokine and chemokine production by COPD sputum cells in vitro

Intensity of macrolide anti-inflammatory activity in J774A.1 cells positively correlates with cellular accumulation and phospholipidosis

Fluorescently labeled macrolides as a tool for monitoring cellular and tissue distribution of azithromycin

The design of novel classes of macrolides for neutrophil-dominated inflammatory diseases

N′-Substituted-2′-O,3′-N-carbonimidoyl Bridged Macrolides: Novel Anti-inflammatory Macrolides without Antimicrobial Activity

Clarithromycin suppresses airway hyperresponsiveness and inflammation in mouse models of asthma

Azithromycin inhibits macrophage interleukin-1β production through inhibition of activator protein-1 in lipopolysaccharide-induced murine pulmonary neutrophilia

Synthesis, activity and pharmacokinetics of novel antibacterial 15-membered ring macrolones

Novel 8a-aza-8a-homoerythromycin—4″-(3-substituted-amino)propionates with broad spectrum antibacterial activity

Valosin containing protein (VCP) interacts with macrolide antibiotics without mediating their anti-inflammatory activities

Immunomodulatory effects of azithromycin on serum amyloid A production in lipopolysaccharide-induced endotoxemia in mice

Differences in assessment of macrolide interaction with human MDR1 (ABCB1, P-gp) using rhodamine-123 efflux, ATPase activity and cellular accumulation assays

Anti-inflammatory effects of macrolide antibiotics

Azithromycin: Mechanisms of action and their relevance for clinical applications

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