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Editorial: Cyclic Nucleotide Phosphodiesterases (PDEs) in Immune Regulation and Inflammation

Frontiers in pharmacology, 2022-07, Vol.13, p.950480-950480

2022

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The Role of PDE8 in T Cell Recruitment and Function in Inflammation

Frontiers in cell and developmental biology, 2021-04, Vol.9, p.636778-636778

2021

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Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies

Biochemical journal, 2006-01, Vol.393 (Pt 1), p.21-41

2006

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Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac

Biochemical journal, 2013-12, Vol.456 (3), p.463-473

2013

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Different phosphodiesterases (PDEs) regulate distinct phosphoproteomes during cAMP signaling

Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (30), p.7741-7743

Epstein, Paul M.

2017

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PDE8 regulates rapid Teff cell adhesion and proliferation independent of ICER

PloS one, 2010-08, Vol.5 (8), p.e12011

2010

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Treatment of Experimental Autoimmune Encephalomyelitis with an Inhibitor of Phosphodiesterase-8 (PDE8)

Cells (Basel, Switzerland), 2022-02, Vol.11 (4), p.660

2022

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Inhibition of breast cancer cell migration by activation of cAMP signaling

Breast cancer research and treatment, 2015-07, Vol.152 (1), p.17-28

2015

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Expression of cGMP-Specific Phosphodiesterase 9A mRNA in the Rat Brain

The Journal of neuroscience, 2001-11, Vol.21 (22), p.9068-9076

2001

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PDE8 controls CD4+ T cell motility through the PDE8A-Raf-1 kinase signaling complex

Cellular signalling, 2017-12, Vol.40, p.62-72

2017

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Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells

Biochemical pharmacology, 2010-02, Vol.79 (3), p.321-329

2010

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Differential Expression and Function of PDE8 and PDE4 in Effector T cells: Implications for PDE8 as a Drug Target in Inflammation

Frontiers in pharmacology, 2016-08, Vol.7, p.259-259

2016

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Effect of cAMP signaling on expression of glucocorticoid receptor, Bim and Bad in glucocorticoid-sensitive and resistant leukemic and multiple myeloma cells

Frontiers in pharmacology, 2015-10, Vol.6, p.230-230

2015

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Phosphodiesterase 8 (PDE8) regulates chemotaxis of activated lymphocytes

Biochemical and biophysical research communications, 2006-06, Vol.345 (2), p.713-719

2006

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Expression of phosphodiesterase 6 (PDE6) in human breast cancer cells

SpringerPlus, 2013-01, Vol.2 (1), p.680, Article 680

2013

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Type 4 cAMP phosphodiesterase (PDE4) inhibitors augment glucocorticoid-mediated apoptosis in B cell chronic lymphocytic leukemia (B-CLL) in the absence of exogenous adenylyl cyclase stimulation

Biochemical pharmacology, 2005-02, Vol.69 (3), p.473-483

2005

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Elevation of intracellular cAMP evokes activity-dependent release of adenosine in cultured rat forebrain neurons

The European journal of neuroscience, 2004-05, Vol.19 (10), p.2669-2681

2004

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Zaprinast stimulates extracellular adenosine accumulation in rat pontine slices

Neuroscience letters, 2004-11, Vol.371 (1), p.12-17

2004

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Expression and regulation of mRNA for distinct isoforms of cAMP-specific PDE-4 in mitogen-stimulated and leukemic human lymphocytes

Cell biochemistry and biophysics, 1998-06, Vol.28 (2-3), p.135-160

1998

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Purification and characterization of high-affinity cyclic adenosine monophosphate phosphodiesterase from dog kidney

Biochemistry (Easton), 1979-11, Vol.18 (23), p.5228-5237

1979

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Structure and promoter activity of the mouse CDC25A gene

Mammalian genome, 2000-12, Vol.11 (12), p.1063-1069

2000

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Policies for accelerating access to clean energy, improving health, advancing development, and mitigating climate change

The Lancet (British edition), 2007-10, Vol.370 (9594), p.1264-1281

2007

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Inhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cells

Proceedings of the National Academy of Sciences - PNAS, 1996-10, Vol.93 (20), p.11236-11241

1996

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Fossil fuels, allergies, and a host of other ills

Journal of allergy and clinical immunology, 2008-09, Vol.122 (3), p.471-472

Epstein, Paul R., MD, MPH

2008

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PDE4 Inhibitors Augment Glucocorticoid-Mediated Apoptosis in B-CLL Cells in the Absence of Exogenous Adenylyl Cyclase Stimulation

Blood, 2004-11, Vol.104 (11), p.4793-4793

2004

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Editorial: Cyclic Nucleotide Phosphodiesterases (PDEs) in Immune Regulation and Inflammation

The Role of PDE8 in T Cell Recruitment and Function in Inflammation

Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies

Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac

Different phosphodiesterases (PDEs) regulate distinct phosphoproteomes during cAMP signaling

PDE8 regulates rapid Teff cell adhesion and proliferation independent of ICER

Treatment of Experimental Autoimmune Encephalomyelitis with an Inhibitor of Phosphodiesterase-8 (PDE8)

Inhibition of breast cancer cell migration by activation of cAMP signaling

Expression of cGMP-Specific Phosphodiesterase 9A mRNA in the Rat Brain

PDE8 controls CD4+ T cell motility through the PDE8A-Raf-1 kinase signaling complex

Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells

Differential Expression and Function of PDE8 and PDE4 in Effector T cells: Implications for PDE8 as a Drug Target in Inflammation

Effect of cAMP signaling on expression of glucocorticoid receptor, Bim and Bad in glucocorticoid-sensitive and resistant leukemic and multiple myeloma cells

Phosphodiesterase 8 (PDE8) regulates chemotaxis of activated lymphocytes

Expression of phosphodiesterase 6 (PDE6) in human breast cancer cells

Type 4 cAMP phosphodiesterase (PDE4) inhibitors augment glucocorticoid-mediated apoptosis in B cell chronic lymphocytic leukemia (B-CLL) in the absence of exogenous adenylyl cyclase stimulation

Elevation of intracellular cAMP evokes activity-dependent release of adenosine in cultured rat forebrain neurons

Zaprinast stimulates extracellular adenosine accumulation in rat pontine slices

Expression and regulation of mRNA for distinct isoforms of cAMP-specific PDE-4 in mitogen-stimulated and leukemic human lymphocytes

Purification and characterization of high-affinity cyclic adenosine monophosphate phosphodiesterase from dog kidney

Structure and promoter activity of the mouse CDC25A gene

Policies for accelerating access to clean energy, improving health, advancing development, and mitigating climate change

Inhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cells

Fossil fuels, allergies, and a host of other ills

PDE4 Inhibitors Augment Glucocorticoid-Mediated Apoptosis in B-CLL Cells in the Absence of Exogenous Adenylyl Cyclase Stimulation

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