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Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

Nature biotechnology, 2013-07, Vol.31 (7), p.638-646

2013

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Therapeutic siRNA silencing in inflammatory monocytes in mice

Nature biotechnology, 2011-11, Vol.29 (11), p.1005-1010

2011

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Delivery of serotonin to the brain by monocytes following phagocytosis of liposomes

Journal of controlled release, 2008-12, Vol.132 (2), p.84-90

2008

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Rab5 is necessary for the biogenesis of the endolysosomal system in vivo

Nature (London), 2012-05, Vol.485 (7399), p.465-470

2012

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Physicochemical parameters affecting liposomal bisphosphonates bioactivity for restenosis therapy: Internalization, cell inhibition, activation of cytokines and complement, and mechanism of cell death

Journal of controlled release, 2010-09, Vol.146 (2), p.182-195

2010

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Prolonged duration local anesthesia with minimal toxicity

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (17), p.7125-7130

2009

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Number-concentration of nanoparticles in liposomal and polymeric multiparticulate preparations: Empirical and calculation methods

Biomaterials, 2006-02, Vol.27 (4), p.651-659

2006

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Predicting in vivo efficacy of potential restenosis therapies by cell culture studies: species-dependent susceptibility of vascular smooth muscle cells

The open cardiovascular medicine journal, 2008-01, Vol.2 (1), p.60-69

2008

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Preparation of Alendronate Liposomes for Enhanced Stability and Bioactivity: In Vitro and In Vivo Characterization

The AAPS journal, 2008-12, Vol.10 (4), p.505-515

2008

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Nanosuspensions of alendronate with gallium or gadolinium attenuate neointimal hyperplasia in rats

Journal of controlled release, 2007-02, Vol.117 (3), p.322-332

2007

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Intravesical Delivery of Small Activating RNA Formulated into Lipid Nanoparticles Inhibits Orthotopic Bladder Tumor Growth

Cancer research (Chicago, Ill.), 2012-10, Vol.72 (19), p.5069-5079

2012

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Alendronate-loaded nanoparticles deplete monocytes and attenuate restenosis

Journal of controlled release, 2006-06, Vol.113 (1), p.23-30

2006

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Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation

Cancer Immunology, Immunotherapy, 2013-02, Vol.62 (2), p.285-297

2013

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A microcomposite hydrogel for repeated on-demand ultrasound-triggered drug delivery

Biomaterials, 2010-07, Vol.31 (19), p.5208-5217

2010

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Liposomal Simvastatin Attenuates Neointimal Hyperplasia in Rats

The AAPS journal, 2010-06, Vol.12 (2), p.181-187

2010

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Liposomal alendronate inhibits systemic innate immunity and reduces in-stent neointimal hyperplasia in rabbits

Circulation (New York, N.Y.), 2003-12, Vol.108 (22), p.2798-2804

2003

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Liposomes for HIV prophylaxis

Biomaterials, 2011-11, Vol.32 (33), p.8663-8668

2011

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An in situ cross-linking hybrid hydrogel for controlled release of proteins

Acta biomaterialia, 2012-05, Vol.8 (5), p.1703-1709

2012

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Alendronate liposomes for antitumor therapy: activation of γδ T cells and inhibition of tumor growth

Advances in experimental medicine and biology, 2012, Vol.733, p.165

2012

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Systemic Depletion of Macrophages by Liposomal Bisphosphonates Reduces Neointimal Formation Following Balloon-Injury in the Rat Carotid Artery

Journal of cardiovascular pharmacology, 2003-11, Vol.42 (5), p.671-679

2003

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Nanospheres of a bisphosphonate attenuate intimal hyperplasia

Journal of nanoscience and nanotechnology, 2006-09, Vol.6 (9-10), p.3226-3234

2006

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Abstract LB-363: Intravesical delivery of lipid nanoparticle formulated p21(Waf1/Cip1) activating dsRNA induces tumor regression and enhances animal survival in a orthotopic bladder cancer model

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.LB-363-LB-363

2012

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31P-NMR and Differential Scanning Calorimetry Studies for Determining Vesicle’s Drug Physical State and Fraction in Alendronate Liposomes

Journal of bioanalysis & biomedicine, 2010-10, Vol.2 (6)

2010

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Abstract 165: RNAi Therapeutics Targeting PCSK9 and ANGPTL3 for Mixed Hyperlipidemia

Arteriosclerosis, thrombosis, and vascular biology, 2012-05, Vol.32 (suppl_1)

2012

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An orthotopic bladder tumor model and the evaluation of intravesical saRNA treatment

Journal of visualized experiments, 2012-07 (65)

2012

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Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

Therapeutic siRNA silencing in inflammatory monocytes in mice

Delivery of serotonin to the brain by monocytes following phagocytosis of liposomes

Rab5 is necessary for the biogenesis of the endolysosomal system in vivo

Physicochemical parameters affecting liposomal bisphosphonates bioactivity for restenosis therapy: Internalization, cell inhibition, activation of cytokines and complement, and mechanism of cell death

Prolonged duration local anesthesia with minimal toxicity

Number-concentration of nanoparticles in liposomal and polymeric multiparticulate preparations: Empirical and calculation methods

Predicting in vivo efficacy of potential restenosis therapies by cell culture studies: species-dependent susceptibility of vascular smooth muscle cells

Preparation of Alendronate Liposomes for Enhanced Stability and Bioactivity: In Vitro and In Vivo Characterization

Nanosuspensions of alendronate with gallium or gadolinium attenuate neointimal hyperplasia in rats

Intravesical Delivery of Small Activating RNA Formulated into Lipid Nanoparticles Inhibits Orthotopic Bladder Tumor Growth

Alendronate-loaded nanoparticles deplete monocytes and attenuate restenosis

Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation

A microcomposite hydrogel for repeated on-demand ultrasound-triggered drug delivery

Liposomal Simvastatin Attenuates Neointimal Hyperplasia in Rats

Liposomal alendronate inhibits systemic innate immunity and reduces in-stent neointimal hyperplasia in rabbits

Liposomes for HIV prophylaxis

An in situ cross-linking hybrid hydrogel for controlled release of proteins

Alendronate liposomes for antitumor therapy: activation of γδ T cells and inhibition of tumor growth

Systemic Depletion of Macrophages by Liposomal Bisphosphonates Reduces Neointimal Formation Following Balloon-Injury in the Rat Carotid Artery

Nanospheres of a bisphosphonate attenuate intimal hyperplasia

Abstract LB-363: Intravesical delivery of lipid nanoparticle formulated p21(Waf1/Cip1) activating dsRNA induces tumor regression and enhances animal survival in a orthotopic bladder cancer model

31P-NMR and Differential Scanning Calorimetry Studies for Determining Vesicle’s Drug Physical State and Fraction in Alendronate Liposomes

Abstract 165: RNAi Therapeutics Targeting PCSK9 and ANGPTL3 for Mixed Hyperlipidemia

An orthotopic bladder tumor model and the evaluation of intravesical saRNA treatment

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